Mechanisms of bone metastasis

Roodman, G. David<sup>1</sup>

Affiliations

¹Department of Medicine, Division of Hematology–Oncology, University of Pittsburgh, the University of Pittsburgh Cancer Institute, and the Department of Veterans Affairs Medical Center — all in Pittsburgh

Links

DOI: 10.1056/NEJMra030831

PubMed: 15084698

WoS: 000220819800010

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Cited By (24)

Year	Entry
2008	Ritchie RO, Koester KJ, Ionova S, Yao W, Lane NE, Ager JW III. Measurement of the toughness of bone: a tutorial with special reference to small animal studies. Bone. November 2008;43(5):798-812.
2020	Bailey S, Hackney D, Vashishth D, Alkalay RN. The effects of metastatic lesion on the structural determinants of bone: current clinical and experimental approaches. Bone. September 2020;138:115159.
2020	Xing L, Ebetino FH, Boeckman RK Jr, Srinivasan V, Tao J, Sawyer TK, Li J, Yao Z, Boyce BF. Targeting anti-cancer agents to bone using bisphosphonates. Bone. September 2020;138:115492.
2021	Monteiro AC, Bonomo A. Dendritic cells development into osteoclast-type APCs by 4T1 breast tumor T cells milieu boost bone consumption. Bone. February 2021;143:115755.
2021	de Nigris F, Ruosi C, Napoli C. Clinical efficiency of epigenetic drugs therapy in bone malignancies. Bone. February 2021;143:115605.
2021	Monteiro AC, Bonomo A. CD8⁺ T cells from experimental in situ breast carcinoma interfere with bone homeostasis. Bone. September 2021;150:116014.
2021	Pagnotti GM, Thompson WR, Guise TA, Rubin CT. Suppression of cancer-associated bone loss through dynamic mechanical loading. Bone. September 2021;150:115998.
2021	Palanca M, Barbanti-Bròdano G, Marras D, Marciante M, Serra M, Gasbarrini A, Dall'Ara E, Cristofolini L. Type, size, and position of metastatic lesions explain the deformation of the vertebrae under complex loading conditions. Bone. October 2021;151:116028.
2022	Ryan C, Stoltzfus KC, Horn S, Chen H, Louie AV, Lehrer EJ, Trifiletti DM, Fox EJ, Abraham JA, Zaorsky NG. Epidemiology of bone metastases. Bone. May 2022;158:115783.
2023	Palanca M, Cavazzoni G, Dall'Ara E. The role of bone metastases on the mechanical competence of human vertebrae. Bone. August 2023;173:116814.
2020	Whyne CM, Ferguson D, Clement A, Rangrez M, Hardisty M. Biomechanical properties of metastatically involved osteolytic bone. Curr Osteoporos Rep. December 2020;18(6):705-715.
2022	Kim HJ, Ryu K-Y, Kim Y-G, Kim MO, Lee JH, Song M-K, Youn Y-J, Pokhrel NK, Kim S-H, Kim J-Y, Jung H-J, Kim W-S, Hong C-W, Kim H-H, Lee Y. Myeloid-specific PTP1B deficiency attenuates inflammation-induced and ovariectomy-induced bone loss in mice by inhibiting osteoclastogenesis. J Bone Miner Res. March 2022;37(3):505-514.
2022	Robertson CL, Ghosh G, Fitzgerald P, Hankey GJ, Levinger I, Golledge J, Almeida OP, Flicker L, Ebeling PR, Yeap BB. Bone turnover markers including undercarboxylated osteocalcin are associated with mortality risk in older men. J Bone Miner Res. August 2022;37(8):1464-1472.
2023	Delgado-Calle J, Roodman GD. Doubling down on Wnt signaling to overcome myeloma bone disease. J Bone Miner Res. June 2023;38(6):812-813.
2010	Stopeck AT, Lipton A, Body J-J, Steger GG, Tonkin K, Lichinitser RH, de Boer M, Fujiwara Y, Yardley DA, Viniegra M, Fan M, Jiang Q, Dansey R, Jun S, Braun A. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. J Clin Oncol. December 10, 2010;28(35):5132-5139.
2012	Mulholland B. The Role of Post-Menopausal Osteoporosis in Bone Metastatic Breast Cancer and the Effect of Monocyte Chemoattractant Protein-1 [PhD thesis]. Brisbane, Australia: Griffith University; April 2012.
2014	Holub O. Biomechanics of Spinal Metastases [PhD thesis]. University of Leeds; April 2014.
2011	Majumdar S. Cell Surface ATP Synthase: A Novel Mechanism for ATP Signaling in Osteoblasts [PhD thesis]. University of Delaware; Summer 2011.
2006	Blouin S. Modèles animaux de perte osseuse bénigne et maligne utilisable pour l'évaluation de biomatériaux [Animal Models of Benign and Malignant Bone Loss Usable in Biomaterial Studies] [PhD thesis]. Université d'Angers; 2006.
2009	Won E. Structural Effects of Photodynamic Therapy and Bisphosphonates on Healthy and Metastatically Involved Vertebral Bone [Master's thesis]. University of Toronto; 2009.
2018	Burke MV. Quantification of Changes in Vertebral Bone Quality in the Presence of Metastases [PhD thesis]. University of Toronto; 2018.
2019	Ma Y-HV. Regulation of Breast Cancer Cells’ Bone-Metastatic Potential by Mechanically Stimulated Osteocytes [PhD thesis]. University of Toronto; 2019.
2019	Mei X. Microfluidic Platform for Investigating Osteocyte Mechanoregulation of Breast Cancer Bone Metastasis [Master's thesis]. University of Toronto; 2019.
2021	Pham T. A Novel Role of HUWE1 in PDGF D Regulation of Bone Marrow Mesenchymal Stem Cell Differentiation [PhD thesis]. Detroit, MI: Wayne State University; 2021.