Can sulci protect the brain from traumatic injury?

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Ho, Johnson¹; Kleiven, Svein¹

Can sulci protect the brain from traumatic injury?

J Biomech. September 18, 2009;42(13):2074-2080

©2009 Elsevier Ltd. All rights reserved

Affiliations

¹Division of Neuronic Engineering, School of Technology and Health, Royal Institute of Technology, Stockholm, Sweden
Abstract and keywords

The influence of sulci in dynamic finite element simulations of the human head has been investigated. First, a detailed 3D FE model was constructed based on an MRI scan of a human head. A second model with a smoothed brain surface was created based on the same MRI scan as the first FE model. These models were validated against experimental data to confirm their human-like dynamic responses during impact. The validated FE models were subjected to several acceleration impulses and the maximum principle strain and strain rate in the brain were analyzed. The results suggested that the inclusion of sulci should be considered for future FE head models as it alters the strain and strain distribution in an FE model.

Keywords: Human head model; Finite element analysis; Cerebral convolution; Traumatic brain injury
Links

DOI: 10.1016/j.jbiomech.2009.06.051

PubMed: 19679308

WoS: 000270478000010
History

Accepted: 2009-06-02

Cited Works (15)

Year	Entry
2006	Cater HL, Sundstrom LE, Morrison B III. Temporal development of hippocampal cell death is dependent on tissue strain but not strain rate. J Biomech. 2006;39(16):2810-2818.
2001	Bradshaw DRS, Morfey CL. Pressure and shear responses in brain injury models. In: Proceedings of the 17th International Technical Conference on the Enhanced Safety of Vehicles (ESV). June 4-7, 2001; Amsterdam, The Netherlands.
1977	Nahum AM, Smith R, Ward CC. Intracranial pressure dynamics during head impact. In: Proceedings of the 21st Stapp Car Crash Conference. October 19-21, 1977; New Orleans, LA. Warrendale, PA: Society of Automotive Engineers:339-366. SAE 770922.
1993	Galbraith JA, Thibault LE, Matteson DR. Mechanical and electrical responses of the squid giant axon to simple elongation. J Biomech Eng. February 1993;115(1):13-22.
1997	Arbogast KB, Margulies SS. Regional differences in mechanical properties of the porcine central nervous system. In: Proceedings of the 41st Stapp Car Crash Conference. November 13-14, 1997; Lake Buena Vista, FL. Warrendale, PA: Society of Automotive Engineers:293-300. SAE 973336.
2000	Bain AC, Meaney DF. Tissue-level thresholds for axonal damage in an experimental model of central nervous system white matter injury. J Biomech Eng. December 2000;122(6):615-622.
2003	Horgan TJ, Gilchrist MD. The creation of three-dimensional finite element models for simulating head impact biomechanics. Int J Crashworthiness. 2003;8(4):353-366.
2007	Kleiven S. Predictors for traumatic brain injuries evaluated through accident reconstructions. Stapp Car Crash J. 2007;51:81-114. SAE 2007-22-0003.
1956	Strich SJ. Diffuse degeneration of the cerebral white matter in severe dementia following head injury. J Neurol Neutrosurg Psychiatry. August 1956;19(3):163-185.
1982	Gennarelli TA, Thibault LE, Adams JH, Graham DI, Thompson CJ, Marcincin RP. Diffuse axonal injury and traumatic coma in the primate. Ann Neurol. 1982;12(6):564-574.
2001	Bradshaw DRS, Ivarsson J, Morfey CL, Viano DC. Simulation of acute subdural hematoma and diffuse axonal injury in coronal head impact. J Biomech. January 2001;34(1):85-94.
2001	Zhang L, Yang KH, Dwarampudi R, Omori K, Li T, Chang K, Hardy WN, Khalil TB, King AI. Recent advances in brain injury research: a new human head model development and validation. Stapp Car Crash J. 2001;45:369-394. SAE 2001-22-0017.
1990	Margulies SS, Thibault LE, Gennarelli TA. Physical model simulations of brain injury in the primate. J Biomech. 1990;23(8):823-836.
2008	Sabet AA, Christoforou E, Zatlin B, Genina GM, Bayly PV. Deformation of the human brain induced by mild angular head acceleration. J Biomech. 2008;41(2):307-315.
1992	Margulies SS, Thibault LE. A proposed tolerance criterion for diffuse axonal injury in man. J Biomech. August 1992;25(8):917-923.

Cited By (18)

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2015	Meaney DF. Biomechanics of brain injury: looking to the future. In: Yoganandan N, Nahum AM, Melvin JW, eds. Accidental Injury: Biomechanics and Prevention. 3rd ed. New York: Springer; 2015:247-257.
2010	Cloots RJH, van Dommelen JAW, Kleiven S, Geers MGD. Traumatic brain injury at multiple length scales: relating diffuse axonal injury to discrete axonal impairment. In: Proceedings of the 2010 International IRCOBI Conference on the Biomechanics of Impact. September 15-17, 2010; Hannover, Germany.119-130.
2019	Sanchez EJ, Gabler LF, Good AB, Funk JR, Crandall JR, Panzer MB. A reanalysis of football impact reconstructions for head kinematics and finite element modeling. Clin Biomech (Bristol, Avon). April 2019;64:82-89.
2015	Tabacu S. Numerical model (switchable/dual model) of the human head for rigid body and finite elements. Comput Methods Biomech Biomed Eng. 2015;18(7):769-781.
2021	Zimmerman KA, Kim J, Karton C, Lochhead L, Sharp DJ, Hoshizaki T, Ghajari M. Player position in American football influences the magnitude of mechanical strains produced in the location of chronic traumatic encephalopathy pathology: a computational modelling study. J Biomech. March 30, 2021;118:110256.
2013	Mao H, Zhang L, Jiang B, Genthikatti VV, Jin X, Zhu F, Makwana R, Gill A, Jandir G, Singh A, Yang KH. Development of a finite element human head model partially validated with thirty five experimental cases. J Biomech Eng. November 2013;135(11):111002.
2012	Rashid B, Destrade M, Gilchrist M. Temperature effects on brain tissue in compression. J Mech Behav Biomed Mater. October 2012;14:113-118.
2021	Sharkey J. Bridging the Gap in Clinical Translation: Optimising an Ovine Model of Traumatic Brain Injury [PhD thesis]. University of Adelaide; June 2021.
2012	Panzer MB. Numerical Simulation of Primary Blast Brain Injury [PhD thesis]. Durham, NC: Duke University; 2012.
2015	Wood GW. Interspecies Scaling in Blast Neurotrauma [PhD thesis]. Duke University; 2015.
2020	Bigler BR. Shock Propagation in Mechanical Models of Traumatic Brain Injury [PhD thesis]. Duke University; 2020.
2013	Begonia MGT. Differentiating the Characteristic Response of the Brain After Exposure to Blunt and Blast Trauma [PhD thesis]. Mississippi State University; December 2013.
2012	Russell CM. A Nonlinear Finite Element Model of the Rat Cervical Spine: Validation and Correlation With Histological Measures of Spinal Cord Injury [Master's thesis]. Vancouver, BC: University of British Columbia; August 2012.
2014	Patton DA. The Biomechanical Determinants of Sports-Related Concussion: Finite Element Simulations of Unhelmeted Head Impacts to Evaluate Kinematic and Tissue-Level Predictors of Injury and Investigate the Design Implications for Soft-Shell Headgear [PhD thesis]. University of New South Wales; March 2014.
2013	Post A. The Influence of Dynamic Response Characteristics on Traumatic Brain Injury [PhD thesis]. Ottawa, ON: University of Ottawa; 2013.
2012	Maltese MR. Traumatic Brain Injury Thresholds in the Pre-Adolescent Juvenile [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2012.
2010	Rafaels KA. Blast Brain Injury Risk [PhD thesis]. Charlottesville, VA: University of Virginia; December 2010.
2020	Giudice JS. Personalized Finite Element Modeling of the Brain: Understanding Subject-Specific Deformation Patterns [PhD thesis]. Charlottesville, VA: University of Virginia; December 2020.