Trabecular texture analysis of CT  images in the relationship with spinal fracture

Ito, Masako; Ohki, Masafumi; Hayashi, Kuniaki; Yamada, Miho; Uetani, Masataka; Nakamura, Takashi

Affiliations

¹Department of Radiology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852 Japan

²Department of Radiology, Nagasaki University School of Dentistry

Abstract

Purpose: To evaluate age-related changes in trabecular texture and bone mineral density (BMD) and to determine the usefulness of texture analysis in the assessment of the risk of fracture.

Materials and Methods: The vertebral trabecular BMD was measured in 209 women aged 18-86 years. Run length analysis was applied to computed tomographic images obtained with 2-mm section thickness. The width of the trabecula (T-texture) and the width of the intertrabecular space (I-texture) were calculated.

Results: I-texture significantly increased with age in women 50 years of age or older (P < .0001). Women with fracture had significantly lower BMD (P < .0001 at 60-69 years, P < .05 at 70-79 years) and significantly higher I-texture (P < .05 at 60-69 years, P < .01 at 70-79 years). For fracture risk, BMD had the highest sensitivity and I-texture had the highest specificity in women aged 60-69 years; I-texture had the highest sensitivity and specificity in women aged 70-79 years.

Conclusion: Texture analysis was helpful in the assessment of fracture risk, especially in elderly women.

Links

DOI: 10.1148/radiology.194.1.7997582

PubMed: 7997582

WoS: A1995PX68400012

History

Received: 1994-04-04

Revised: 1994-06-01

Accepted: 1994-07-22

Online: 1994-08-03

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Cited By (15)

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1998	Ito M, Nakamura T, Matsumoto T, Tsurusaki K, Hayashi K. Analysis of trabecular microarchitecture of human iliac bone using microcomputed tomography in patients with hip arthrosis with or without vertebral fracture. Bone. August 1998;23(2):163-169.
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1996	Genant HK, Engelke K, Fuerst T, Glüer C, Grampp S, Harris ST, Jergas M, Lang T, Lu Y, Majumdar S, Mathur A, Takada M. Noninvasive assessment of bone mineral and structure: state of the art. J Bone Miner Res. June 1996;11(6):707-730.
1997	Majumdar S, Genant HK, Grampp S, Newitt DC, Truong V-H, Lin JC, Mathur A. Correlation of trabecular bone structure with age, bone mineral density, and osteoporotic status: in vivo studies in the distal radius using high resolution magnetic resonance imaging. J Bone Miner Res. January 1997;12(1):111-118.
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