| 2001 |
Fritton SP, Rubin CT. Dense bone tissue as a molecular composite. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:8-1–8-41. |
1 |
1 |
| 1990 |
Rubin CT, McLeod KJ. Biologic modulation of mechanical influences in bone remodeling. In: Mow VC, Ratcliffe A, Woo SL-Y, eds. Biomechanics of Diarthrodial Joints. Vol 2. New York, NY: Springer-Verlag; 1990:97-118. |
7 |
5 |
| 1994 |
Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994. |
1 |
1 |
| 2001 |
Fajardo RJ, Müller R. Three‐dimensional analysis of nonhuman primate trabecular architecture using micro‐computed tomography. Am J Phys Anthropol. 2001;115(4):327-336. |
26 |
25 |
| 1997 |
Fritton JC, Rubin CT, Qin Y-X, McLeod KJ. Whole-body vibration in the skeleton: development of a resonance-based testing device. Ann Biomed Eng. September–October 1997;25(5):831-839. |
17 |
7 |
| 2002 |
Qin Y-X, Lin W, Rubin C. The pathway of bone fluid flow as defined by in vivo intramedullary pressure and streaming potential measurements. Ann Biomed Eng. May 2002;30(5):693-702. |
25 |
21 |
| 2003 |
Judex S, Boyd S, Qin Y-X, Turner S, Ye K, Müller R, Rubin C. Adaptations of trabecular bone to low magnitude vibrations result in more uniform stress and strain under load. Ann Biomed Eng. January 2003;31(1):12-20. |
26 |
12 |
| 1999 |
Iwamoto J, Yeh JK, Aloia JF. Differential effect of treadmill exercise on three cancellous bone sites in the young growing rat. Bone. March 1999;24(3):163-169. |
22 |
21 |
| 2002 |
Rubin C, Turner AS, Mallinckrodt C, Jerome C, Mcleod K, Bain S. Mechanical strain, induced noninvasively in the high-frequency domain, is anabolic to cancellous bone, but not cortical bone. Bone. March 2002;30(3):445-452. |
43 |
33 |
| 2006 |
Xie L, Jacobson JM, Choi ES, Busa B, Donahue LR, Miller LM, Rubin CT, Judex S. Low-level mechanical vibrations can influence bone resorption and bone formation in the growing skeleton. Bone. November 2006;39(5):1059-1066. |
33 |
20 |
| 2021 |
Komatsu DE, Duque E, Hadjiargyrou M. MicroRNAs and fracture healing: pre-clinical studies. Bone. February 2021;143:115758. |
0 |
0 |
| 2021 |
Pagnotti GM, Thompson WR, Guise TA, Rubin CT. Suppression of cancer-associated bone loss through dynamic mechanical loading. Bone. September 2021;150:115998. |
0 |
0 |
| 2023 |
Chirokikh AA, Uddin SMZ, Areikat N, Jones R, Duque E, Connor C, Hadjiargyrou M, Thanos PK, Komatsu DE. Combined methylphenidate and fluoxetine treatment in adolescent rats significantly impairs weight gain with minimal effects on skeletal development. Bone. February 2023;167:116637. |
0 |
0 |
| 1992 |
Rubin CT, Bain SD, McLeod KJ. Suppression of the osteogenic response in the aging skeleton. Calcif Tiss Int. April 1992;50(4):306-313. |
50 |
46 |
| 2005 |
Busa B, Miller LM, Rubin CT, Qin Y-X, Judex S. Rapid establishment of chemical and mechanical properties during lamellar bone formation. Calcif Tiss Int. December 2005;77(6):386-394. |
25 |
18 |
| 1994 |
Rubin CT, McLeod KJ. Promotion of bony ingrowth by frequency-specific, low-amplitude mechanical strain. Clin Orthop Relat Res. January 1994;298:165-174. |
55 |
43 |
| 1992 |
Jay GD. Characterization of a bovine synovial fluid lubricating factor, I: chemical, surface activity and lubricating properties. Connect Tissue Res. 1992;28(1-2):71-88. |
31 |
31 |
| 2003 |
Judex S, Boyd S, Qin Y-X, Miller L, Müller R, Rubin C. Combining high-resolution micro-computed tomography with material composition to define the quality of bone tissue. Curr Osteoporos Rep. June 2003;1(1):11-19. |
31 |
16 |
| 2001 |
Rubin C, Xu G, Judex S. The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely low‐magnitude mechanical stimuli. FASEB J. October 2001;15(12):2225-2229. |
40 |
20 |
| 2002 |
Judex S, Donahue L, Rubin C. Genetic predisposition to low bone mass is paralleled by an enhanced sensitivity to signals anabolic to the skeleton. FASEB J. August 2002;16(10):1280-1282. |
36 |
16 |
| 2006 |
Rubin J, Rubin C, Jacobs CR. Molecular pathways mediating mechanical signaling in bone. Gene. February 15, 2006;367:1-16. |
41 |
34 |
| 2012 |
Thompson WR, Rubin CT, Rubin J. Mechanical regulation of signaling pathways in bone. Gene. July 25, 2012;503(2):179-193. |
31 |
27 |
| 1990 |
Rubin CT, McLeod KJ, Bain SD. Functional strains and cortical bone adaptation: epigenetic assurance of skeletal integrity. J Biomech. 1990;23(suppl 1):43-54. |
35 |
31 |
| 1990 |
Brown TD, Pedersen DR, Gray ML, Brand RA, Rubin CT. Toward an identification of mechanical parameters initiating periosteal remodeling: a combined experimental and analytic approach. J Biomech. 1990;23(9):893-905. |
47 |
33 |
| 1992 |
Gross TS, McLeod KJ, Rubin CT. Characterizing bone strain distributions in vivo using three triple rosette strain gages. J Biomech. September 1992;25(9):1081-1087. |
52 |
43 |
| 1997 |
Adams DJ, Spirt AA, Brown TD, Fritton SP, Rubin CT, Brand RA. Testing the daily stress stimulus theory of bone adaptation with natural and experimentally controlled strain histories. J Biomech. July 1997;30(7):671-678. |
24 |
15 |
| 2000 |
Fritton SP, McLeod KJ, Rubin CT. Quantifying the strain history of bone: spatial uniformity and self-similarity of low-magnitude strains. J Biomech. March 2000;33(3):317-325. |
83 |
63 |
| 2003 |
Qin Y-X, Kaplan T, Saldanha A, Rubin C. Fluid pressure gradients, arising from oscillations in intramedullary pressure, is correlated with the formation of bone and inhibition of intracortical porosity. J Biomech. October 2003;36(10):1427-1437. |
48 |
36 |
| 2005 |
Mittra E, Rubin C, Qin Y-X. Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone. J Biomech. June 2005;38(6):1229-1237. |
32 |
31 |
| 2007 |
Judex S, Lei X, Han D, Rubin C. Low-magnitude mechanical signals that stimulate bone formation in the ovariectomized rat are dependent on the applied frequency but not on the strain magnitude. J Biomech. 2007;40(6):1333-1339. |
31 |
21 |
| 2008 |
Mittra E, Rubin C, Gruber B, Qin Y-X. Evaluation of trabecular mechanical and microstructural properties in human calcaneal bone of advanced age using mechanical testing, μCT, and DXA. J Biomech. 2008;41(2):368-375. |
13 |
12 |
| 2011 |
Sen B, Xie Z, Case N, Styner M, Rubin CT, Rubin J. Mechanical signal influence on mesenchymal stem cell fate is enhanced by incorporation of refractory periods into the loading regimen. J Biomech. February 24, 2011;44(4):593-599. |
14 |
7 |
| 2006 |
Mittra E, Akella S, Qin Y-X. The effects of embedding material, loading rate and magnitude, and penetration depth in nanoindentation of trabecular bone. J Biomed Mater Res. October 2006;A79(1):86-93. |
26 |
25 |
| 1996 |
Rubin C, Gross T, Qin Y-X, Fritton S, Guilak F, McLeod K. Differentiation of the bone-tissue remodeling response to axial and torsional loading in the turkey ulna. J Bone Joint Surg. October 1996;78A(11):1665-1676. |
15 |
13 |
| 2019 |
Grover K, Hu M, Lin L, Muir J, Qin Y-X. Functional disuse initiates medullary endosteal micro-architectural impairment in cortical bone characterized by nanoindentation. J Bone Min Metab. November 2019;37(6):1048-1057. |
1 |
1 |
| 1995 |
Rubin CT, Gross TS, McLeod KJ, Bain SD. Morphologie stages in lamellar bone formation stimulated by a potent mechanical stimulus. J Bone Miner Res. March 1995;10(3):488-495. |
29 |
20 |
| 1995 |
Donahue HJ, McLeod KJ, Rubin CT, Andersen J, Grine EA, Hertzberg EL, Brink PR. Cell-to-cell communication in osteoblastic networks: cell line–dependent hormonal regulation of gap junction function. J Bone Miner Res. June 1995;10(6):881-889. |
23 |
19 |
| 1997 |
Gross TS, Edwards JL, Mcleod KJ, Rubin CT. Strain gradients correlate with sites of periosteal bone formation. J Bone Miner Res. June 1997;12(6):982-988. |
59 |
51 |
| 2002 |
Rubin C, Turner AS, Müller R, Mittra E, McLeod K, Lin W, Qin Y. Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention. J Bone Miner Res. February 2002;17(2):349-357. |
57 |
37 |
| 2004 |
Rubin C, Recker R, Cullen D, Ryaby J, McCabe J, McLeod K. Prevention of postmenopausal bone loss by a low‐magnitude, high‐frequency mechanical stimuli: a clinical trial assessing compliance, efficacy, and safety. J Bone Miner Res. March 2004;19(3):343-351. |
53 |
38 |
| 2004 |
Ward K, Alsop C, Caulton J, Rubin C, Adams J, Mughal Z. Low magnitude mechanical loading is osteogenic in children with disabling conditions. J Bone Miner Res. March 2004;19(3):360-369. |
36 |
23 |
| 2004 |
Judex S, Garman R, Squire M, Donahue L, Rubin C. Genetically based influences on the site‐specific regulation of trabecular and cortical bone morphology. J Bone Miner Res. April 2004;19(4):600-606. |
33 |
19 |
| 2004 |
Judex S, Garman R, Squire M, Busa B, Donahue L-R, Rubin C. Genetically linked site-specificity of disuse osteoporosis. J Bone Miner Res. April 2004;19(4):607-613. |
33 |
26 |
| 2006 |
Gilsanz V, Wren TAL, Sanchez M, Dorey F, Judex S, Rubin C. Low‐level, high‐frequency mechanical signals enhance musculoskeletal development of young women with low bmd. J Bone Miner Res. September 2006;21(9):1464-1474. |
29 |
16 |
| 2007 |
Miller LM, Little W, Schirmer A, Sheik F, Busa B, Judex S. Accretion of bone quantity and quality in the developing mouse skeleton. J Bone Miner Res. July 2007;22(7):1037-1045. |
46 |
41 |
| 2009 |
Luu YK, Capilla E, Rosen CJ, Gilsanz V, Pessin JE, Judex S, Rubin CT. Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity. J Bone Miner Res. January 2009;24(1):50-61. |
25 |
10 |
| 2016 |
Cabahug-Zuckerman P, Frikha-Benayed D, Majeska RJ, Tuthill A, Yakar S, Judex S, Schaffler MB. Osteocyte apoptosis caused by hindlimb unloading is required to trigger osteocyte RANKL production and subsequent resorption of cortical and trabecular bone in mice femurs. J Bone Miner Res. July 2016;31(7):1356-1365. |
28 |
25 |
| 2020 |
Ochs‐Balcom HM, Hovey KM, Andrews C, Cauley JA, Hale L, Li W, Bea JW, Sarto GE, Stefanick ML, Stone KL, Watts NB, Zaslavsky O, Wactawski‐Wende J. Short sleep is associated with low bone mineral density and osteoporosis in the women's health initiative. J Bone Miner Res. February 2020;35(2):261-268. |
6 |
4 |
| 2003 |
Lieberman DE, Pearson OM, Polk JD, Demes B, Crompton AW. Optimization of bone growth and remodeling in response to loading in tapered mammalian limbs. J Exp Biol. September 15, 2003;206(18):3125-3138. |
22 |
19 |
| 1994 |
Guilak F. Volume and surface area measurement of viable chondrocytes in situ using geometric modelling of serial confocal sections. J Microsc (Oxford). March 1994;173(3):245-256. |
42 |
34 |
| 2014 |
Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, O'Ryan F. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw: 2014 update. J Oral Maxillofac Surg. October 2014;72(10):1938-1956. |
31 |
31 |
| 1995 |
Gross TS, Rubin CT. Uniformity of resorptive bone loss induced by disuse. J Orthop Res. September 1995;13(5):708-714. |
14 |
8 |
| 1998 |
Qin Y, Rubin CT, McLeod KJ. Nonlinear dependence of loading intensity and cycle number in the maintenance of bone mass and morphology. J Orthop Res. July 1998;16(4):482-489. |
50 |
28 |
| 1999 |
Guilak F, Zell RA, Erickson GR, Grande DA, Rubin CT, McLeod KJ, Donahue HJ. Mechanically induced calcium waves in articular chondrocytes are inhibited by gadolinium and amiloride. J Orthop Res. May 1999;17(3):421-429. |
26 |
20 |
| 2007 |
Garman R, Gaudette G, Donahue L-R, Rubin C, Judex S. Low-level accelerations applied in the absence of weight bearing can enhance trabecular bone formation. J Orthop Res. June 2007;25(6):732-740. |
18 |
11 |
| 2022 |
He G, Ricca JM, Dai AZ, Mustahsan VM, Cai Y, Bielski MR, Kao I, Khan FA. A novel bone registration method using impression molding and structured-light 3D scanning technology. J Orthop Res. October 2022;40(10):2340-2349. |
1 |
1 |
| 2022 |
He G, Dai AZ, Mustahsan VM, Shah AT, Li L, Khan JA, Bielski MR, Komatsu DE, Kao I, Khan FA. A novel method of light projection and modular jigs to improve accuracy in bone sarcoma resection. J Orthop Res. November 2022;40(11):2522-2536. |
0 |
0 |
| 2008 |
Fuchs RK, Allen MR, Ruppel ME, Diab T, Phipps RJ, Miller LM, Burr DB. In situ examination of the time-course for secondary mineralization of Haversian bone using synchrotron Fourier transform infrared microspectroscopy. Matrix Biol. January 2008;27(1):34-41. |
21 |
19 |
| 2010 |
Ozcivici E, Luu YK, Adler B, Qin Y-X, Rubin J, Judex S, Rubin CT. Mechanical signals as anabolic agents in bone. Nat Rev Rheumatol. January 2010;6(1):50-59. |
32 |
23 |
| 2001 |
Rubin C, Turner AS, Bain S, Mallinckrodt C, McLeod K. Low mechanical signals strengthen long bones. Nature. August 9, 2001;412(6847):603-604. |
75 |
53 |
| 2006 |
Jackson RD, LaCroix AZ, Gass M, Wallace RB, Robbins J, Lewis CE, Bassford T, Beresford SAA, Black HR, Blanchette P, Bonds DE, Brunner RL, Brzyski RG, Caan B, Cauley JA, Chlebowski RT, Cummings SR, Granek I, Hays J, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Johnson KC, Judd H, Kotchen JM, Kuller LH, Langer RD, Lasser NL, Limacher MC, Ludlam S, Manson JE, Margolis KL, McGowan J, Ockene JK, O’Sullivan MJ, Phillips L, Prentice RL, Sarto GE, Stefanick ML, Van Horn L, Wactawski-Wende J, Whitlock E, Anderson GL, Assaf AR, Barad D; Women’s Health Initiative Investigators. Calcium plus vitamin D supplementation and the risk of fractures. NEJM. February 16, 2006;354(7):669-683. |
28 |
23 |
| 2008 |
Ruppel ME, Miller LM, Burr DB. The effect of the microscopic and nanoscale structure on bone fragility. Osteoporos Int. September 2008;19(9):1251-1265. |
22 |
21 |
| 1994 |
Best BA, Guilak F, Setton LA, Zhu W, Saed-Nejad F, Ratcliffe A, Weidenbaum M, Mow VC. Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition. Spine. January 15, 1994;19(2):212-221. |
59 |
43 |
| 2003 |
Rubin CP, Pope M, Fritton C, Magnusson M, Hansson T, McLeod K. Transmissibility of 15-Hertz to 35-Hertz vibrations to the human hip and lumbar spine: determining the physiologic feasibility of delivering low-level anabolic mechanical stimuli to skeletal regions at greatest risk of fracture because of osteoporosis. Spine. December 1, 2003;28(23):2621-2627. |
19 |
18 |
| 1990 |
Bain SD, Impeduglia TM, Rubin CT. Cement line staining in undecalcified thin sections of cortical bone. Stain Tech. 1990;65(4):159-163. |
8 |
5 |