Bone mineral lies mainly outside collagen fibrils: predictions of a composite model for osternal bone

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Pidaparti, R. M. V.¹; Chandran, A.¹; Takano, Y.²; Turner, C. H.^1,3

Bone mineral lies mainly outside collagen fibrils: predictions of a composite model for osternal bone

J Biomech. July 1996;29(7):909-916

©1996 Elsevier Science Ltd.

Affiliations

¹Department of Mechanical Engineering, Purdue University

²Department of Anatomy, Indiana University Medical Center

³Department of Orthopaedic Surgery, Indiana University Medical Center, Biomechanics and Biomaterials Research Center, IUPUI Indianapolis, IN 46202, U.S.A.
Abstract and keywords

We propose that the elastic properties of osteonal bone can be modeled accurately as a simple fiber-reinforced composite, provided that accurate properties for the mineral and collagen phases of the ultrastructure are available. Off-axis stiffness coefficients were measured in anterior quadrant of canine femora at 10° increments from longitudinal to transverse direction using an acoustic microscope. The resolution of these measurements was about 60 μm or less than the radius of one osteon. The bone specimens were subsequently demineralized and the off-axis measurements were repeated to determine the elasticity of bone collagen. Bone collagen fibrils were not principally aligned along the long axis of the bone, but demonstrated an alignment that was 30° from the long axis. A simple composite model was developed based on the experimental data. The model that best fit experimental data assumed that (1) bone collagen was aligned 30° from the long axis of the bone, (2) 75% of mineral crystals reside outside of collagen fibrils, and (3) mineral crystals outside of collagen fibrils have their c-axis in the longitudinal direction.

Keywords: Bone; Acoustic microscopy; Collagen; Composite
Links

DOI: 10.1016/0021-9290(95)00147-6

PubMed: 8809621

WoS: A1996UV35000008
History

Received: 1995-08-31

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