Continued development of computational models and biofidelic anthropomorphic test devices (ATDs) necessitates further analysis of the effects of bracing on an occupant’s biomechanical response in automobile collisions. A total of 20 dynamic sled tests were performed, 10 low (2.5 g, Δv = 4.8 kph) and 10 medium severity (5.0 g, Δv = 9.7 kph), with five male human volunteers of approximately 50th percentile male height and weight. Each volunteer was exposed to two impulses at each severity, one relaxed and one braced prior to the impulse. A Vicon motion analysis system, 12 MX-T20 2 megapixel cameras, was used to quantify subject 3D kinematics (±1 mm) (1 kHz). Excursions of select anatomical regions were normalized to their respective initial positions and compared by test condition. At the low severity, bracing significantly reduced (p < 0.05) the forward excursion of the knees, hips, elbows, shoulders, and head (average 35–70%). At the medium severity, bracing significantly reduced (p < 0.05) the forward excursion of the elbows, shoulders, and head (average 36–69%). Although not significant, bracing at the medium severity considerably reduced the forward excursion of the knees and hips (average 18–26%). This study illustrates that bracing has a significant influence on the biomechanical response of human occupants in frontal sled tests and provides novel biomechanical data that can be used to refine and validate computational models and ATDs used to assess injury risk in automotive collisions.