Nowadays more and more effort is being spent on the research and development of motorcycle safety improvements. Among these improvements are motorcycle airbag systems. Although a few airbag-equipped motorcycles have been built, the technology is still in a research stage. Along with full scale testing, computer simulations can be a successful tool for studying and optimizing these systems. This paper gives a state of the art impression on research and development activities in the field of motorcycle airbag systems. Further the combined multibody-finite element approach offered by the Crash Victim Simulation program MADYMO is applied for modelling the motorcycle-airbag-rider interaction. Both a model of a motorcycle sled mock-up and a complete model of an airbag-equipped motorcycle were developed. The first model is the mathematical counterpart of an actual sled test, representing a 90° frontal impact between a motorcycle and a passenger car side structure, involving a pre-inflated airbag. Based on the correlation found between sled test and simulation results, it is expected that the full airbag-equipped motorcycle model can be used for performance evaluation of different motorcycle airbag restraint systems under different impact conditions.