The objective of this paper is to give an overview of the injury patterns of belted occupants as a function of different collision scenarios in a major accident sample. 1,100 car to car accidents involving major bodily injuries (AIS 2+) have been analyzed for the research on the injury pattern and injury costs of belted car occupants in isolated frontal, side and rear-end collisions. 41 accidents with airbag-equipped cars fulfilling the selection criteria were analyzed for purposes of comparison.