Impact velocity and chest compression are important factors in traumatic iniury; however, there is no functional relationship to assess impact severity. A blunt thoracic impact ol constant velocity (5-22 m/s) and prescribed contact displacement (3-46 mm) was delivered to 123 anesthetized rabbits. Myocardial and maior vascular iniury incroasod from contusion to rupture with cardiac tamponade and sudden doath as eithor impact velocity or chest compression was independently increased. A theoretical relationship was found for impact severity: IS=VC/1-C where V and C are impact velocity and normalized chest compression. Based on the frequency of critical/fatal iniury, problt analysis gave IS=6.4 m/s as an estimate of the ED₅₀ response in the experimental model.