wbldb
home
|
authors
|
theses
van der Meulen, M. C. H.
1,2
;
Jepsen, K. J.
3
; Mikić, B.
4
Understanding bone strength: size isn’t everything
Bone
. July 2001;29(1):101-104
©2001 Elsevier Science Inc. All rights reserved.
Affiliations
1
Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA
2
Biomechanics and Biomaterials Section, Research Division, Hospital for Special Surgery, New York, NY, USA
3
Department of Orthopedics,
Mount Sinai School of Medicine
, New York, NY, USA
4
Picker Engineering Program, Smith College, Northampton, MA, USA
Links
DOI:
10.1016/S8756-3282(01)00491-4
PubMed:
11502469
WoS:
000170696700001
History
Received: 2000-11-15
Revised: 2001-02-16
Accepted: 2001-03-20
Cited Works (16)
Year
Entry
1996
Jepsen KJ, Goldstein SA, Kuhn JL, Schaffler MB, Bonadio J. Type‐I collagen mutation compromises the post‐yield behavior of Mov13 long bone.
J Orthop Res
. May 1996;14(3):493-499.
2000
McCreadie BR, Goldstein SA. Biomechanics of fracture: is bone mineral density sufficient to assess risk?
J Bone Miner Res
. December 2000;15(12):2305-2308.
1970
Timoshenko SP, Goodier JN.
Theory of Elasticity
. 3rd ed. New York, NY: McGraw-Hill Book Co; 1970.
2000
Akhter MP, Iwaniec UT, Covey MA, Cullen DM, Kimmel DB, Recker RR. Genetic variations in bone density, histomorphometry, and strength in mice.
Calcif Tiss Int
. October 2000;67(4):337-344.
1999
Boskey AL, Wright TM, Blank RD. Collagen and bone strength.
J Bone Miner Res
. March 1999;14(3):330-335.
1982
Rubin CT, Lanyon LE. Limb mechanics as a function of speed and gait: a study of functional strains in the radius and tibia of horse and dog.
J Exp Biol
. December 1982;101:187-211.
1996
Beamer WG, Donahue LR, Rosen CJ, Baylink DJ. Genetic variability in adult bone density among inbred strains of mice.
Bone
. May 1996;18(5):397-403.
1999
Brodt MD, Ellis CB, Silva MJ. Growing C57Bl/6 mice increase whole bone mechanical properties by increasing geometric and material properties.
J Bone Miner Res
. December 1999;14(12):2159-2166.
1990
Bonadio J, Saunders TL, Tsai E, Goldstein SA, Morris-Wiman J, Brinkley L, Dolan DF, Altschuler RA, Hawkins JE Jr, Bateman JF, Mascara T, Jaenisch R. Transgenic mouse model of the mild dominant form of osteogenesis imperfecta.
Proc Natl Acad Sci USA
. September 1990;87(18):7145-7149.
1997
Jepsen KJ, Schaffler MB, Kuhn JL, Goulet RW, Bonadio J, Goldstein SA. Type I collagen mutation alters the strength and fatigue behavior of Mov13 cortical tissue.
J Biomech
. November–December 1997;30(11-12):1141-1147.
1993
van der Meulen MCH, Beaupré GS, Carter DR. Mechanobiologic influences in long bone cross-sectional growth.
Bone
. July–August 1993;14(4):635-642.
1998
Akhter MP, Cullen DM, Pedersen EA, Kimmel DB, Recker RR. Bone response to in vivo mechanical loading in two breeds of mice.
Calcif Tiss Int
. November 1998;63(5):442-449.
2000
Turner CH, Hsieh Y, Müller R, Bouxsein ML, Baylink DJ, Rosen CJ, Grynpas MD, Donahue LR, Beamer WG. Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice.
J Bone Miner Res
. June 2000;15(6):1126-1131.
1993
Bonadio J, Jepsen KJ, Mansoura MK, Jaenisch R, Kuhn JL, Goldstein SA. A murine skeletal adaptation that significantly increases cortical bone mechanical properties: implications for human skeletal fragility.
J Clin Invest
. October 1993;92(4):1697-1705.
1993
Keaveny TM, Hayes WC. A 20-year perspective on the mechanical properties of trabecular bone.
J Biomech Eng
. November 1993;115(4B):534-542.
1993
Turner CH, Burr DB. Basic biomechanical measurements of bone: a tutorial.
Bone
. 1993;14(4):595-608.
Cited By (43)
Year
Entry
2006
Ruff C, Holt B, Trinkaus E. Who's afraid of the big bad Wolff? "Wolff's law" and bone functional adaptation.
Am J Phys Anthropol
. April 2006;129(4):484-498.
2006
Hernandez CJ, Keaveny TM. A biomechanical perspective on bone quality.
Bone
. December 2006;39(6):1173-1181.
2006
Nyman JS, Roy A, Acuna RL, Gayle HJ, Reyes MJ, Tyler JH, Dean DD, Wang X. Age-related effect on the concentration of collagen crosslinks in human osteonal and interstitial bone tissue.
Bone
. December 2006;39(6):1210-1217.
2008
Nyman JS, Ni Q, Nicolella DP, Wang X. Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone.
Bone
. January 2008;42(1):193-199.
2013
Burket JC, Brooks DJ, MacLeay JM, Baker SP, Boskey AL, van der Meulen MCH. Variations in nanomechanical properties and tissue composition within trabeculae from an ovine model of osteoporosis and treatment.
Bone
. January 2013;52(1):326-336.
2005
Busa B, Miller LM, Rubin CT, Qin Y-X, Judex S. Rapid establishment of chemical and mechanical properties during lamellar bone formation.
Calcif Tiss Int
. December 2005;77(6):386-394.
2010
Donnelly E, Chen DX, Boskey AL, Baker SP, van der Meulen MCH. Contribution of mineral to bone structural behavior and tissue mechanical properties.
Calcif Tiss Int
. November 2010;87(5):450-460.
2011
Donnelly E. Methods for assessing bone quality: a review.
Clin Orthop Relat Res
. August 2011;469:2128-2138.
2011
Cole JH, van der Meulen MCH. Whole bone mechanics and bone quality.
Clin Orthop Relat Res
. August 2011;469(8):2139-2149.
2016
Hunt HB, Donnelly E. Bone quality assessment techniques: geometric, compositional, and mechanical characterization from macroscale to nanoscale.
Clin Rev Bone Miner Metab
. September 2016;14(3):133-149.
2004
Silva MJ, Brodt MD, Fan Z, Rho J-Y. Nanoindentation and whole-bone bending estimates of material properties in bones from the senescence accelerated mouse SAMP6.
J Biomech
. November 2004;37(11):1639-1646.
2010
Main RP, Lynch ME, van der Meulen MCH. In vivo tibial stiffness is maintained by whole bone morphology and cross-sectional geometry in growing female mice.
J Biomech
. October 19, 2010;43(14):2689-2694.
2011
Bi X, Patil CA, Lynch CC, Pharr GM, Mahadevan-Jansen A, Nyman JS. Raman and mechanical properties correlate at whole bone- and tissue-levels in a genetic mouse model.
J Biomech
. January 11, 2011;44(2):297-303.
2005
Boskey AL, Mendelsohn R. Infrared analysis of bone in health and disease.
J Biomed Opt
. May–June 2005;10(3):031102.
2004
Eckstein F, Wunderer C, Boehm H, Kuhn V, Priemel M, Link TM, Lochmüller E-M. Reproducibility and side differences of mechanical tests for determining the structural strength of the proximal femur.
J Bone Miner Res
. March 2004;19(3):379-385.
2005
Tommasini SM, Morgan TG, van der Meulen MCH, Jepsen KJ. Genetic variation in structure‐function relationships for the inbred mouse lumbar vertebral body.
J Bone Miner Res
. May 2005;20(5):817-827.
2007
Glatt V, Canalis E, Stadmeyer L, Bouxsein ML. Age‐related changes in trabecular architecture differ in female and male C57BL/6J mice.
J Bone Miner Res
. August 2007;22(8):1197-1207.
2015
Jepsen KJ, Silva MJ, Vashishth D, Guo XE, van der Meulen MCH. Establishing biomechanical mechanisms in mouse models: practical guidelines for systematically evaluating phenotypic changes in the diaphyses of long bones.
J Bone Miner Res
. June 2015;30(6):951-966.
2007
Nyman JS, Roy A, Tyler JH, Acuna RL, Gayle HJ, Wang X. Age‐related factors affecting the postyield energy dissipation of human cortical bone.
J Orthop Res
. May 2007;25(7):646-655.
2003
Jepsen KJ, Akkus OJ, Majeska RJ, Nadeau JH. Hierarchical relationship between bone traits and mechanical properties in inbred mice.
Mamm Genome
. February 2003;14(2):97-104.
2017
Unal M.
Classification of Bound Water and Collagen Denaturation Status of Cortical Bone by Raman Spectroscopy
[PhD thesis]. Cleveland, OH: Case Western Reserve University; January 2017.
2006
Fritton JC.
Mechanical Loading Induced Adaptation of the Mouse Tibia
[PhD thesis]. Ithaca, NY: Cornell University; January 2006.
2013
Burket JC.
Alterations in Tissue Composition and Nanomechanical Properties With Ageing, Osteoporosis, and Treatment
[PhD thesis]. Ithaca, NY: Cornell University; January 2013.
2014
Melville KM.
Estrogen Receptor Alpha in Osteoblasts Mediates Bone Mass and Bone's Response to in Vivo Loading
[PhD thesis]. Ithaca, NY: Cornell University; August 2014.
2018
Chen JTH.
Alterations in Bone Tissue Properties With Parathyroid Hormone Treatment
[PhD thesis]. Ithaca, NY: Cornell University; May 2018.
2018
Hunt HB.
Characterization of Material Properties, Microarchitecture, and Mechanics of Bone from Subjects With Type 2 Diabetes Mellitus
[PhD thesis]. Ithaca, NY: Cornell University; December 2018.
2019
Arora D.
Characterization of Bone Structural, Geomteric, and Material Properties in the TallyHO Mouse Model of Type 2 Diabetes Mellitus
[Master's thesis]. Ithaca, NY: Cornell University; December 2019.
2008
Tommasini SM.
Phenotypic Integration Contributes to Skeletal Functionality and Fragility
[PhD thesis]. New York, NY: The City University of New York; 2008.
2015
Weatherholt AM.
Translational Studies Into the Effects of Exercise on Estimated Bone Strength
[PhD thesis]. Indianapolis, IN: Indiana University; September 2015.
2021
Scott MC.
Exercise and Bone: Older Adults, Type II Diabetes, and Ketogenic Diets
[PhD thesis]. Louisiana State University; May 2021.
2017
Mathavan N.
The Anabolic - Anti-Catabolic Paradigm of Augmenting Skeletal Regeneration: A Bone Quality Perspective
[PhD thesis]. Lund, Sweden: Lund University; 2017.
2004
Giangregorio L.
Musculoskeletal Changes After Spinal Cord Injury: Effects of Body Weight Supported Treadmill Training
[PhD thesis]. Hamilton, ON: McMaster University; November 2004.
2008
Courtland H-W.
Intra-Species Variation in Skeletal Mechanical Function is Achieved Through Genetic Regulation of Both the Quality and Morphology of Bone
[PhD thesis]. Mount Sinai School of Medicine; 2008.
2008
Price C.
Systems Based Approaches to Identifying How Genetically Varying Skeletal Growth Affects Skeletal Functionality and Fragility
[PhD thesis]. Mount Sinai School of Medicine; 2008.
2017
McCormick CM.
Altered Trabecular Microarchitecture Near the Glenohumeral Joint of a Rat Model With Neonatal Brachial Plexus Injury
[Master's thesis]. North Carolina State University; 2017.
2019
Hanne NJ.
Characterizing Osteovascular Structure and Function With High Fat Diet-Induced Obesity and Stroke
[PhD thesis]. North Carolina State University; 2019.
2016
Berman AG.
Influence of Mechanical Stimulation on the Quantity and Quality of Bone During Modeling
[Master's thesis]. Purdue University; August 2016.
2019
Powell KM.
The Effects of Zoledronate and Raloxifene Combination Therapy on Diseased Mouse Bone
[Master's thesis]. Indianapolis, IN: Purdue University; May 2019.
2012
Acerbo AS.
Local Chemical and Nanostructural Properties of Rat Cortical Bone Are Altered by Osteoporosis and Pharmaceutical Treatments
[PhD thesis]. Stony Brook, NY: Stony Brook University; August 2012.
2014
Butler TA.
The Effects of Post Pubertal Food Restriction on Bone Architecture, Strength, and Medullary Adipose Composition
[PhD thesis]. Temple University; January 2014.
2016
Vrahna C.
Investigating the Effects of Downstream Parathyroid Hormone (PTH) Targets on Bone Strength and Quality
[PhD thesis]. Melbourne, Australia: The University of Melbourne; December 2016.
2010
Beckstrom AB.
Histologic and Geometric Data Challenge the Assumption of Habitual Superior-Inferior (tension-Compression) Bending Across the Chimpanzee Proximal Femur
[Master's thesis]. University of Utah; August 2010.
2018
Zhang L.
Effects of Osteoblast-Specific Gα
S
Overexpression on Skeletal Development and Response to Catabolic and Anabolic Stimuli Using a Transgenic Mouse Model
[PhD thesis]. University of Toronto; 2018.