Prediction of mechanical properties of the cancellous bone of the mandibular condyle

van Ruijven, L. J.; Giesen, E. B. W.; Farella, M.; van Eijden, T. M. G. J.

Affiliations

¹Department of Functional Anatomy, Academic Center for Dentistry Amsterdam (ACTA), Meibergdreef 15, 1105 AZ Amsterdam, the Netherlands

²Department of Orthodontics and Oral Biology, University Medical Centre Nijmegen, Nijmegen, the Netherlands

³Department of Orthodontics, University of Naples "Federico II", Naples, Italy

Abstract and keywords

The mechanical properties of cancellous bone depend on the bone structure. The present study examined the extent to which the apparent stiffness of the cancellous bone of the human mandibular condyle can be predicted from its structure. Two models were compared. The first, a structure model, used structural parameters such as bone volume fraction and anisotropy to estimate the apparent stiffness. The second was a finite element model (FEM) of the cancellous bone. The bone structure was characterized by micro-computed tomography. The calculated stiffnesses of 24 bone samples were compared with measured stiffnesses. Both models could predict 89% of the variation in the measured stiffnesses. From the stiffness approximated by FEM in combination with the measured stiffness, the stiffness of the bone tissue was estimated to be 11.1 ± 3.2 GPa. It was concluded that both models could predict the stiffness of cancellous bone with adequate accuracy.

Keywords: cancellous bone; mandible; finite element model; apparent Young's modulus

Links

DOI: 10.1177/154405910308201011

PubMed: 14514763

WoS: 000185608500011

History

Received: 2002-10-09

Revised: 2003-05-30

Accepted: 2003-07-25

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2018	Wu D, Isaksson P, Ferguson SJ, Persson C. Young’s modulus of trabecular bone at the tissue level: a review. Acta Biomater. September 15, 2018;78:1.
2007	van Ruijven LJ, Mulder L, van Eijden TMGJ. Variations in mineralization affect the stress and strain distributions in cortical and trabecular bone. J Biomech. 2007;40(6):1211-1218.
2007	Mulder L, van Ruijven LJ, Koolstra JH, van Eijden TMGJ. Biomechanical consequences of developmental changes in trabecular architecture and mineralization of the pig mandibular condyle. J Biomech. 2007;40(7):1575-1582.
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2014	Chen Y, Pani M, Taddei F, Mazzà C, Li X, Viceconti M. Large-scale finite element analysis of human cancellous bone tissue micro computer tomography data: a convergence study. J Biomech Eng. October 2014;136(10):101013.
2005	Day JS. Bone Quality: The Mechanical Effects of Microarchitecture and Matrix Properties [PhD thesis]. Erasmus University Rotterdam; 2005.
2012	Hamed E. Multiscale Modeling of Elastic Moduli and Strength of Bone [PhD thesis]. University of Illinois at Urbana-Champaign; 2012.
2019	Du J. Mechanical Adaptation of Human Trabecular Bone: Experimental and Computational Study [PhD thesis]. Loughborough University; 2019.
2020	O’Sullivan LM. Time-Sequence of Biomechanical Adaption in Trabecular Tissue During Estrogen Deficiency [PhD thesis]. National University of Ireland Galway; March 2020.
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2011	Willard VP. Characterization of the Temporomandibular Joint Disc and Fibrocartilage Engineering Using Human Embryonic Stem Cells [PhD thesis]. Houston, TX: Rice University; May 2011.