This study presents three validation cases of the Global Human Body Models Consortium (GHBMC) mid-sized male model (M50) – full body sled tests at two speeds, and a lateral drop test. The lateral sled tests involved propelling a seated cadaver into a rigid wall at 6.7 m/s and 8.9 m/s. Drop tests were performed from 1 m above a rigid surface. Model results were compared to force vs. time curves, peak force, and number of fractures from the studies. For the 6.7 m/s impact, the peak thoracic, abdominal and pelvic loads were 8.7 kN, 3.1 kN and 14.9 kN for the model and 6.0±1.1 kN, 3.6±1.3 kN, and 5.1±2.5 kN for the tests (n = 3). Similarly, in the 8.9 m/s case they were 12.6 kN, 6.1 kN, and 21.9 kN for the model and 8.75±4.5 kN (n=6), 5.0±2.0 kN (n=8), and 15.0±4.5 kN (n=8) for the experiments. The peak thorax load in the drop test was 6.7 kN for the model and the range was 5.8 kN to 7.4 kN in the cadavers. When analyzing rib fractures, the model predicted Abbreviated Injury Scale (AIS) 3 thoracic injury in the 6.7 m/s sled test while the test subjects injuries ranged from AIS 0 to 4. In the 8.9 m/s sled test, the model predicted AIS 4 thoracic injury which matched the AIS scores in 7 of the 8 test subjects. In both sled test cases the model also predicted pelvic fractures while none were reported in the literature. The model predicted an ilio-ramus fracture in both cases in addition to ischio pubic ramus and sacrum fractures in the 8.9 m/s case. The model predicted 2 rib fractures in the drop test, which is within the reported range of 0 to 5 fractures for male subjects. These results provide confidence in the GHBMC model’s performance in lateral impacts.