The objective of this study was to provide new biomechanical response data for the thorax with lateral and oblique loading, so as to support the development of safety systems for side impact protection that would offer the level of protection that has been achieved in frontal impact. Three male human cadavers were successively impacted by an impactor system delivering a constant velocity impact from the left and the right sides at three levels (shoulder, upper chest and mid-chest). Different impact directions were also chosen for each side:​ lateral, +15° posterolateral, -15° anterolateral. One subject was impacted at 1, 3 and 6 m/s whereas the other two subjects were impacted at 3 m/s only. A total of nineteen tests was performed. The impact force and the chest lateral deflection were measured using respectively a standard data acquisition system and also an optoelectronic stereophotogrammetric system (OSS). After each test, attempts were made to detect rib fractures by palpation, and a necropsy of the torso was performed after the tests series to document the injuries produced by all the tests. Overall, the peak impact force increased from the lowest impact level (mid-chest) to the highest (shoulder) and was found to be rate-sensitive. The force-deflection relationship was non linear for the shoulder impacts (stiffness increased with increasing deflection) whereas stiffness was nearly constant for the mid- and upper-chest impacts. The anterolateral impacts to the mid- and upper-chest generated more rib fractures than the other impact directions.