Finite element analysis of traumatic brain injuries mechanisms in the rat

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Baumgartner, D.¹; Lamy, M.¹; Willinger, R.¹; Choquet, P.²; Goetz, C.²; Constantinesco, A.²; Davidsson, J.³

Finite element analysis of traumatic brain injuries mechanisms in the rat

Proceedings of the 2009 International IRCOBI Conference on the Biomechanics of Impact

Affiliations

¹University of Strasbourg – Institute for Fluid and Solid Mechanics – France

²University of Strasbourg – University Hospital – France

³Chalmers University of Technology – Sweden
Abstract and keywords

A finite element model of the rat’s head was developed to improve the knowledge on traumatic brain injuries. A parametric study was conducted on the mechanical characteristics of its anatomical components. A correlation was then established between observed injuries on one hand and intracranial stresses on the other. This result is mainly based on experimental well-defined impacts that generate high rotational accelerations of the head in the sagittal plane. This approach shows the power of numerical tools for better understanding of injury mechanisms and thus for design of protection devices against extreme mechanical loadings of the human body.

Keywords: Traumatic brain injuries; Small animal; Finite element method

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Cited By (7)

Year	Entry
2011	Lamy M, Baumgartner D, Willinger R, Yoganandan N, Stemper BD. Study of mild traumatic brain injuries using experiments and finite element modeling. In: 55th Annual Proceedings, Association for the Advancement of Automotive Medicine (AAAM). October 3-5, 2011; Paris, France.125-135.
2013	Lamy M, Baumgartner D, Davidsson J, Willinger R. Traumatic brain injury investigation using FE modeling of the rat and experimental high amplitude rotations in the sagittal plane. In: Proceedings of the 2013 International IRCOBI Conference on the Biomechanics of Injury. September 11-13, 2013; Gothenburg, Sweden.456-469.
2014	Ren L, Baumgartner D, Davidsson J, Yang J, Willinger R. Effect of the inhomogeneous brain mechanical characteristic on dynamic responses of head under trauma. In: Proceedings of the 2014 International IRCOBI Conference on the Biomechanics of Injury. September 10-12, 2014; Berlin, Germany.93-105.
2013	Antona-Makoshi J. Reanalysis of Primate Head Impact Experiments to Clarify Mild Traumatic Brain Injury Kinematics and Thresholds [PhD thesis]. Götenburg, Sweden: Chalmers University of Technology; 2013.
2016	Antona-Makoshi J. Traumatic Brain Injuries: Animal Experiments and Numerical Simulations to Support the Development of a Brain Injury Criterion [PhD thesis]. Götenburg, Sweden: Chalmers University of Technology; 2016.
2014	Patton DA. The Biomechanical Determinants of Sports-Related Concussion: Finite Element Simulations of Unhelmeted Head Impacts to Evaluate Kinematic and Tissue-Level Predictors of Injury and Investigate the Design Implications for Soft-Shell Headgear [PhD thesis]. University of New South Wales; March 2014.
2015	Singh D. Investigation of Primary Blast Injury and Protection Using Sagittal and Transverse Finite Element Head Models [Master's thesis]. University of Waterloo; 2015.