Volumetric changes of articular cartilage during stress relaxation in unconfined compression

wbldb

Wong, M.¹; Ponticiello, M.¹; Kovanen, V.²; Jurvelin, J. S.^1,3

Volumetric changes of articular cartilage during stress relaxation in unconfined compression

J Biomech. September 2000;33(9):1049-1054

©2000 Elsevier Science B.V. All rights reserved.

Affiliations

¹M.E. Mueller Institute for Biomechanics, University of Bern, Postfach 30, Murtenstrasse, 35, 3010 Bern, Switzerland

²Department of Health Sciences, University of Jyväskylä, P.O. Box 35, 40351 Jyväskylä , Finland

³Department of Clinical Physiology, Kuopio University Hospital, P.O. Box 1777, Kuopio, Finland
Abstract and keywords

The time-dependent lateral expansion and load relaxation of cartilage cylinders subjected to unconfined compression were simultaneously recorded. These measurements were used to (1) test the assumption of incompressibility for articular cartilage, (2) measure the Poisson's ratio of articular cartilage in compression and (3) investigate the relationship between stress relaxation and volumetric change. Mechanical tests were performed on fetal, calf, and adult humeral head articular cartilage. The instantaneous Poisson's ratio of adult cartilage was 0.49±0.08 (mean+S.D.), thus confirming the assumption of incompressibility for this tissue. The instantaneous Poisson's ratio was significantly lower for calf (0.38±0.04) and fetal cartilage (0.36±0.04). The equilibrium Poisson's ratio, i.e. true Poisson's ratio of the solid matrix, was significantly higher for the adult tissue (0.26±0.11) compared to both the fetal (0.09±0.02) and calf (0.11±0.03) cartilage. A linear relationship between time-matched load and lateral expansion after the first minute of stress relaxation was observed.

Keywords: Cartilage; Mechanical testing; Incompressibility; Volume change; Poisson's ratio
Links

DOI: 10.1016/S0021-9290(00)00084-1

PubMed: 10854876

WoS: 000088811400001
History

Accepted: 2000-03-27

Cited Works (11)

Year	Entry
1978	Venn MF. Variation of chemical composition with age in human femoral head cartilage. Ann Rheum Dis. April 1978;37(2):168-174.
1991	Athanasiou KA, Rosenwasser MP, Buckwalter JA, Malinin TI, Mow VC. Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilage. J Orthop Res. May 1991;9(3):330-340.
1970	Muir H, Bullough P, Maroudas A. The distribution of collagen in human articular cartilage with some of its physiological implications. J Bone Joint Surg. August 1970;52B(3):554-563.
1980	Mow VC, Kuei SC, Lai WM, Armstrong CG. Biphasic creep and stress relaxation of articular cartilage in compression: theory and experiments. J Biomech Eng. February 1980;102(1):73-84.
1986	Mizrahi J, Maroudas A, Lanir Y, Ziv I, Webber TJ. The “instantaneous” deformation of cartilage: effects of collagen fiber orientation and osmotic stress. Biorheology. 1986;23(4):311-330.
1997	Khalsa PS, Eisenberg SR. Compressive behavior of articular cartilage is not completely explained by proteoglycan osmotic pressure. J Biomech. June 1997;30(6):589-594.
1976	Hori RY, Mockros LF. Indentation tests of human articular cartilage. J Biomech. 1976;9(4):259-268.
1989	Mow VC, Gibbs MC, Lai WM, Zhu WB, Athanasiou KA. Biphasic indentation of articular cartilage, II: a numerical algorithm and an experimental study. J Biomech. 1989;22:853-861.
1988	Eyre DR, Dickson IR, Van Ness K. Collagen cross-linking in human bone and articular cartilage: age-related changes in the content of mature hydroxypyridinium residues. Biochem J. June 1988;252(2):495-500.
1971	Kempson GE, Spivey CJ, Swanson SAV, Freeman MAR. Patterns of cartilage stiffness on normal and degenerate human femoral heads. J Biomech. December 1971;4(6):597-609.
1971	Hayes WC, Mockros LF. Viscoelastic properties of human articular cartilage. J Appl Physiol. October 1971;31(4):562-568.

Cited By (40)

Year	Entry
2004	Roy R, Kohles SS, Zaporojan V, Peretti GM, Randolph MA, Xu J, Bonassar LJ. Analysis of bending behavior of native and engineered auricular and costal cartilage. J Biomed Mater Res. March 2004;A68A(4):597-602.
2007	Asanbaeva A, Masuda K, Thonar EJ-MA, Klisch SM, Sah RL. Mechanisms of cartilage growth: modulation of balance between proteoglycan and collagen in vitro using chondroitinase ABC. Arthritis Rheum. January 2007;56(1):188-198.
2002	Wang CC-B, Guo XE, Sun D, Mow VC, Ateshian GA, Hung CT. The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach. Biorheology. 2002;39(1-2):11-25.
2001	DiSilvestro MR, Suh J-KF. A cross-validation of the biphasic poroviscoelastic model of articular cartilage in unconfined compression, indentation, and confined compression. J Biomech. April 2001;34(4):519-525.
2002	Korhonen RK, Laasanen MS, Töyräs J, Rieppo J, Hirvonen J, Helminen HJ, Jurvelin JS. Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation. J Biomech. July 2002;35(7):903-909.
2004	Ateshian GA, Chahine NO, Basalo IM, Hung CT. The correspondence between equilibrium biphasic and triphasic material properties in mixture models of articular cartilage. J Biomech. March 2004;37(3):391-400.
2004	Chahine NO, Wang CC-B, Hung CT, Ateshian GA. Anisotropic strain-dependent material properties of bovine articular cartilage in the transitional range from tension to compression. J Biomech. August 2004;37(8):1251-1261.
2001	DiSilvestro MR, Zhu Q, Wong M, Jurvelin JS, Suh J-KF. Biphasic poroviscoelastic simulation of the unconfined compression of articular cartilage, I: simultaneous prediction of reaction force and lateral displacement. J Biomech Eng. April 2001;123(2):191-197.
2002	Elliott DM, Narmoneva DA, Setton LA. Direct measurement of the Poisson’s ratio of human patella cartilage in tension. J Biomech Eng. April 2002;124(2):223-228.
2016	Robinson DL, Kersh ME, Walsh NC, Ackland DC, de Steiger RN, Pandy MG. Mechanical properties of normal and osteoarthritic human articular cartilage. J Mech Behav Biomed Mater. August 2016;61:96-109.
2003	Williamson AK, Chen AC, Masuda K, Thonar EJ, Sah RL. Tensile mechanical properties of bovine articular cartilage: variations with growth and relationships to collagen network components. J Orthop Res. September 2003;21(5):872-880.
2004	Krishnan R, Kopacz M, Ateshian GA. Experimental verification of the role of interstitial fluid pressurization in cartilage lubrication. J Orthop Res. May 2004;22(3):565-570.
2004	Park S, Hung CT, Ateshian GA. Mechanical response of bovine articular cartilage under dynamic unconfined compression loading at physiological stress levels. Osteoarthritis Cartilage. January 2004;12(1):65-73.
2010	Forman JL, Del Pozo de Dios E, Kent RW. A pseudo-elastic effective material property representation of the costal cartilage for use in finite element models of the whole human body. Traffic Inj Prev. 2010;11(6):613-622.
2001	Wang C. Digital Video Microscopy-Based Determination of Cartilage Inhomogeneity, Anisotropy and Tension -Compression Nonlinearity: Implications on Chondrocyte Environment [PhD thesis]. Columbia University; 2001.
2004	Krishnan R. Role of Interstitial Fluid Pressurization in Articular Cartilage Lubrication [PhD thesis]. Columbia University; 2004.
2006	Chahine NO. Multi-Scale Measurements of the Mechanical and Transport Properties of Native and Engineered Articular Cartilage [PhD thesis]. Columbia University; 2006.
2007	Wan Q. Fundamental Theoretical and Experimental Studies for Applications Toward Functional Tissue Engineering of Articular Cartilage [PhD thesis]. Columbia University; 2007.
2008	Ng KW. Biomimetic Engineered Cartilage: Recreating the in Vivo Collagen Network and Depth-Dependent Inhomogeneity [PhD thesis]. Columbia University; 2008.
2015	Giorgi M. Mechanobiological Predictions of Fetal Joint Morphogenesis [PhD thesis]. Imperial College London; April 2015.
2003	Korhonen R. Experimental Analysis and Finite Element Modeling of Normal and Degraded Articular Cartilage: Mechanical Response of Poroelastic, Anisotropic and Inhomogenous Tissue [PhD thesis]. University of Kuopio; 2003.
2007	Wu BYC. Investigation of Long-Term Cyclic Loading Effects on Initially Intact Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2007.
2012	Vahdati A. Role of Fixation and Mechanical Properties of Implanted Cartilage Replacements in Integrative Repair of Articular Cartilage Injuries [PhD thesis]. University of Notre Dame; September 2012.
2010	Wosu R. Extraction et analyse comparative des propriétés mécaniques intrinsèques des plaques de croissance porcines à quatre stades développementaux [Master's thesis]. École polytechnique de Montréal; December 2010.
2021	Pahoff S. Fibre-Reinforced Hydrogels for Functional Cartilage Tissue Engineering [PhD thesis]. Queensland University of Technology; 2021.
2007	June RK II. Polymer Dynamics as a Mechanism of Cartilage Flow-Independent Viscoelasticity [PhD thesis]. Davis, University of California; December 2007.
2009	Mejia KL. The Effect of Long-Term Storage on the Relaxation Properties of Articular Cartilage [Master's thesis]. Davis, University of California; 2009.
2010	Anderson MJ. Effects of Glycation on Dynamic Mechanical Properties and Penetration of Articular Cartilage [Master's thesis]. Davis, University of California; 2010.
2001	DiMicco MA. Collagen Synthesis, Transport, and Deposition in Integrative Articular Cartilage Repair [PhD thesis]. San Diego (UCSD), University of California; 2001.
2002	Williamson AK. Development and Growth of Bovine Articular Cartilage: Biomechanical Function and Function-Composition Relationships [PhD thesis]. San Diego (UCSD), University of California; 2002.
2006	Asanbaeva A. Cartilage Growth and Remodeling: Modulation of Growth Phenotype and Tensile Integrity [PhD thesis]. San Diego (UCSD), University of California; 2006.
2012	Chan EFT. Association of 3-Dimensional Joint Shape and Function During Growth, Repair, and in Disease [PhD thesis]. San Diego (UCSD), University of California; 2012.
2014	Su W-iA. Biomechanics of Osteochondral Graft Insertion: Cartilage Damage and Protection Strategies [PhD thesis]. San Diego (UCSD), University of California; 2014.
2013	Deneweth JM. Mapping the Biomechanical Properties of Human Knee Cartilage [PhD thesis]. University of Michigan; 2013.
2015	Robinson DL. Mechanical Properties of Normal and Osteoarthritic Human Articular Cartilage [PhD thesis]. University of Melbourne; 2015.
2007	Anderson AE. Computational Modeling of Hip Joint Mechanics [PhD thesis]. University of Utah; April 2007.
2013	Henak CR. Cartilage and Labrum Mechanics in the Normal and Pathomorphologic Human Hip [PhD thesis]. University of Utah; August 2013.
2009	Forman J. The Structural Characteristics of the Costal Cartilage: The Roles of Calcification and the Perichondrium, and the Representation of the Costal Cartilage in Finite Element Models of the Human Body [PhD thesis]. Charlottesville, VA: University of Virginia; August 2009.
2009	Tripathy S. An Indentation Study of Costal Cartilage Using Atomic Force Microscopy [PhD thesis]. Charlottesville, VA: University of Virginia; May 2009.
2019	Han G. Energy Dissipation and Failure in Articular Cartilage [PhD thesis]. University of Wisconsin – Madison; 2019.