Integrins:​ versatility, modulation, and signaling in cell adhesion

Hynes, Richard O.<sup>1</sup>

Year	Entry
2013	Hum JM. Signaling Mechanisms That Suppress the Anabolic Response of Osteoblasts and Osteocytes to Fluid Shear Stress [PhD thesis]. Bloomington, IN: Indiana University; September 2013.
1994	Ingber DE. Cellular tensegrity and mechanochemical transduction. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:329-342.
1998	Pavalko FM, Chen NX, Turner CH, Burr DB, Atkinson S, Hsieh Y-F, Qiu J, Duncan RL. Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions. Am J Physiol. December 1998;275(6):C1591-C1601.
2009	McNamara LM, Majeska RJ, Weinbaum S, Friedrich V, Schaffler MB. Attachment of osteocyte cell processes to the bone matrix. Anat Rec. March 2009;292(3):355-363.
1999	Rowley JA, Madlambayan G, Mooney DJ. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials. January 1999;20(1):45-53.
1995	Duncan RL, Turner CH. Mechanotransduction and the functional response of bone to mechanical strain. Calcif Tiss Int. December 1995;57(5):344-358.
2002	Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell. September 20, 2002;110(6):673-687.
2003	Silver FH, Freeman JW, Seehra GP. Collagen self-assembly and the development of tendon mechanical properties. J Biomech. October 2003;36(10):1529-1553.
2006	Wang JH-C. Mechanobiology of tendon. J Biomech. 2006;39(9):1563-1582.
1997	Salter DM, Robb JE, Wright MO. Electrophysiological responses of human bone cells to mechanical stimulation: evidence for specific integrin function in mechanotransduction. J Bone Miner Res. July 1997;12(7):1133-1141.
1997	Toma CD, Ashkar S, Gray ML, Schaffer JL, Gerstenfeld LC. Signal transduction of mechanical stimuli is dependent on microfilament integrity: identification of osteopontin as a mechanically induced gene in osteoblasts. J Bone Miner Res. October 1997;12(10):1626-1636.
2004	Pennington DE. Integrin Expression and Fibronectin Matrix Assembly During in Vitro Chondrogenesis [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2004.
2002	Sun D. Theoretical and Experimental Investigations of the Mechano-Electrochemical Properties of Articular Cartilage, a Charged -Hydrated -Soft, Biological Tissue [PhD thesis]. Columbia University; 2002.
2005	Takai E. Modulation of Bone Cell Mechanotransduction [PhD thesis]. Columbia University; 2005.
2017	Shah AD. Elucidating the Effects of Interstitial Fluid Flow on Hepatocellular Carcinoma Invasion [PhD thesis]. Drexel University; June 2017.
2001	Baer AE. The Micromechanical Environment of Intervertebral Disc Cells [PhD thesis]. Duke University; 2001.
2009	Gilchrist CL. The Effects of Extracellular Matrix Mechanics and Composition on the Behaviors of Nucleus Pulposus Cells from the Intervertebral Disc [PhD thesis]. Duke University; 2009.
2015	Hwang PY. Cadherin-Mediated Cell-Cell Interactions Regulates Phenotype and Morphology of Nucleus Pulposus Cells of the Intervertebral Disc [PhD thesis]. Duke University; 2015.
2002	Tate MC. The Development of Extracellular Matrix Based Neural Stem Cell Transplants for Treatment of Traumatic Brain Injury [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2002.
2004	Gallant ND. Analysis of Integrin-Mediated Cell Adhesion Strengthening Using Surfaces Engineered to Control Cell Shape and Focal Adhesion Assembly [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; November 2004.
2004	Benjamin G. Keselowsky. Engineering Surfaces to Direct Integrin Binding and Signaling to Promote Osteoblast Differentiation [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; May 2004.
2006	Reyes CD. Collagen- and Fibronectin-Mimetic Integrin-Specific Surfaces That Promote Osseointegration [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2006.
2018	Cermeño EA. Adhesion Signature Based Enrichment of Tumor Initiating Cells [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2018.
1997	Bhatia SN. Controlling Cell-Cell Interactions in Hepatic Tissue Engineering Using Microfabrication [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1997.
2008	Chai DH. Progression of Chondrocyte Signaling Responses to Mechanical Stimulation in 3-D Gel Culture [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2008.
1998	Rezania A. Biomimetic Peptide Surfaces That Enhance Bone Cell Adhesion and Formation of Mineralized Tissue [PhD thesis]. Evanston, IL: Northwestern University; December 1998.
2003	Harbers GM. Biomimetic Surface Engineering to Study Osteoblast Adhesion and Matrix Mineralization [PhD thesis]. Evanston, IL: Northwestern University; December 2003.
2014	Steward AJ. The Mechanotransduction of Hydrostatic Pressure by Mesenchymal Stem Cells [PhD thesis]. University of Notre Dame; April 2014.
2018	Mahzoon S. Chondroinductive Biomaterials for Stem Cell Differentiation [PhD thesis]. University of Oklahoma; 2018.
2011	Surrao DC. Biomimetic Scaffolds for Ligament Tissue Engineering [PhD thesis]. Queen's University; December 2011.
2010	Janeiro C. The Effect of Bone Quality on Osteoclastic Bone Resorption [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; May 2010.
1998	Reid DL. The Distribution and Function of Collagen Receptors on Bovine Articular Chondrocytes [PhD thesis]. Rush University; 1998.
2001	Joseph RM. Comparison of Fibronectin and Fibronectin Fragment Interactions With the Chondrocyte [PhD thesis]. Rush University; 2001.
2002	Prino-Mello A. Migration of Lymphoma and Lymphocyte T Cells on Flat and Grooved Microfabricated Surfaces: Comparative Analysis of Peripheral Blood T Lymphocytes and Lymphoma Human T Cell Line HUT78 [PhD thesis]. Trinity College Dublin; November 2002.
1997	Chien Y-W. Effects of Calcitriol and Its Analogs on Protein Expression in Osteoblast-Like Cell Lines: ROS17/2.8, MG-63, and MC3T3-E1 [PhD thesis]. University of Alabama at Birmingham; 1997.
2009	Han SK. In Situ Chondrocyte Mechanics and Numerical Modeling [PhD thesis]. Calgary, AB: University of Calgary; April 2009.
2014	Jablonski CL. Integrin Α1β1 Participates in Chondrocyte Transduction of Osmotic Stress [Master's thesis]. Calgary, AB: University of Calgary; May 2014.
2007	Li YJ. Culture of Human Embryonic Stem Cells on Peptide Functionalized Polymer Networks [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2007.
1996	Adams DJ. Mechanical Factors Initiating Appositional Bone Formation [PhD thesis]. University of Iowa; May 1996.
2004	Taboas JM. Mechanobiologic Regulation of Skeletal Progenitor Cell Differentiation [PhD thesis]. University of Michigan; 2004.
1995	El-Ghannam AR. Synthesis and Characterization of Template Material for Optimal in Vitro Synthesis of Bone-Like Tissue [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1995.
1996	García AJ. Quantitative Analysis of Fibronectin-Mediated Adhesion of Osteoblast-Like Cells to Bioactive Glass and Hydroxyapatite [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1996.
1998	Lu HH. 45S5 Bioactive Glass Surface Zeta Potential Variations in Electrolyte Solutions With and Without Fibronectin [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1998.
2005	Lee MH. Optimization of Surface-Immobilized Peptide/protein Presentation for Control of the Biological Activity of Substrates for Tissue Engineering Applications [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2005.
2021	Speer JE. Engineering Nucleus Pulposus Cell-Matrix Interactions With Laminin Ligands for Tissue Regeneration [PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2021.