Mechanical behavior of articular cartilage:​ quantitative changes with alteration of ionic environment

Parsons, J. R.; Black, J.

Affiliations

¹Department of Orthopaedic Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19174, U.S.A.

²Present address: Section of Orthopaedic Surgery, College of Medicine and Dentistry of New Jersey - New Jersey Medical School, Newark, NJ 07103, U.S.A.

Abstract

The in vitro viscoelastic mechanical response of normal rabbit articular cartilage is quantitatively altered by changes in the ionic concentration of the test environment. Experimental results indicate that specific functional relationships exist between shear moduli, retardation time spectra and ionic concentration. The forms of these relationships are consistent with the structure and physio-chemical composition of the tissue.

Links

DOI: 10.1016/0021-9290(79)90162-3

PubMed: 489627

WoS: A1979HP15200004

History

Received: 1978-06-19

Cited Works (8)

Year	Entry
1970	Muir H, Bullough P, Maroudas A. The distribution of collagen in human articular cartilage with some of its physiological implications. J Bone Joint Surg. August 1970;52B(3):554-563.
1976	Torzilli PA, Mow VC. On the fundamental fluid transport mechanisms through normal and pathological articular cartilage during function, II: the analysis, solution and conclusions. J Biomech. 1976;9(9):587-606.
1977	Parsons JR, Black J. The viscoelastic shear behavior of normal rabbit articular cartilage. J Biomech. 1977;10(1):21-29.
1965	Linn FC, Sokoloff L. Movement and composition of interstitial fluid of cartilage. Arthritis Rheum. August 1965;8(4):481-494.
1976	Mansour JM, Mow VC. The permeability of articular cartilage under compressive strain and at high pressures. J Bone Joint Surg. June 1976;58A(4):509-516.
1972	Hayes WC, Keer LM, Herrmann G, Mockros LF. A mathematical analysis for indentation tests of articular cartilage. J Biomech. September 1972;5(5):541-551.
1976	Torzilli PA, Mow VC. On the fundamental fluid transport mechanisms through normal and pathological articular cartilage during function, I: the formulation. J Biomech. 1976;9(8):541-552.
1963	Elmore SM, Sokoloff L, Norris G, Carmeci P. Nature of “imperfect” elasticity of articular cartilage. J Appl Physiol. 1963;18(2):393-396.

Cited By (37)

Year	Entry
1990	Mow VC, Hou JS, Owens JM, Ratcliffe A. Biphasic and quasilinear viscoelastic theories for hydrated soft tissues. In: Mow VC, Ratcliffe A, Woo SL-Y, eds. Biomechanics of Diarthrodial Joints. Vol 1. New York, NY: Springer-Verlag; 1990:215-260.
1990	Lai WM, Hou JS, Mow VC. A triphasic theory for the swelling properties of hydrated charged soft biological tissues. In: Mow VC, Ratcliffe A, Woo SL-Y, eds. Biomechanics of Diarthrodial Joints. Vol 1. New York, NY: Springer-Verlag; 1990:283-312.
1987	Jurvelin J, Kiviranta I, Arokoski J, Tammi M, Helminen HJ. Indentation study of the biomechanical properties of articular cartilage in the canine knee. Eng Med. January 1987;16(1):15-22.
1984	Mow VC, Holmes MH, Lai WM. Fluid transport and mechanical properties of articular cartilage: a review. J Biomech. 1984;17(5):377-394.
1987	Mak AF, Lai WM, Mow VC. Biphasic indentation of articular cartilage, I: theoretical analysis. J Biomech. 1987;20(7):703-714.
1990	Kwan MK, Lai WM, Mow VC. A finite deformation theory for cartilage and other soft hydrated connective tissues, I: equilibrium results. J Biomech. 1990;23(2):145-155.
1990	Jurvelin J, Kiviranta I, Säämänen A-M, Tammi M, Helminen HJ. Indentation stiffness of young canine knee articular cartilage: influence of strenuous joint loading. J Biomech. 1990;23(12):1239-1246.
1992	Chimich D, Shrive N, Frank C, Marchuk L, Bray R. Water content alters viscoelastic behaviour of the normal adolescent rabbit medial collateral ligament. J Biomech. August 1992;25(8):831-837.
1984	Myers ER, Lai WM, Mow VC. A continuum theory and an experiment for the ion-induced swelling behavior of articular cartilage. J Biomech Eng. May 1984;106(2):151-158.
1986	Mak AF. The apparent viscoelastic behavior of articular cartilage: the contributions from the intrinsic matrix viscoelasticity and interstitial fluid flows. J Biomech Eng. May 1986;108(2):123-130.
1987	Eisenberg SR, Grodzinsky AJ. The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. J Biomech Eng. February 1987;109(1):79-89.
1991	Lai WM, Hou JS, Mow VC. A triphasic theory for the swelling and deformation behaviors of articular cartilage. J Biomech Eng. August 1991;113(3):245-258.
2003	Detamore MS, Athanasiou KA. Tensile properties of the porcine temporomandibular joint disc. J Biomech Eng. August 2003;125(4):558-565.
2008	Singh M, Detamore MS. Tensile properties of the mandibular condylar cartilage. J Biomech Eng. February 2008;130(1):011009.
1981	Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties. J Biomech Eng. November 1981;103(2):280-292.
1985	Eisenberg SR, Grodzinsky AJ. Swelling of articular cartilage and other connective tissues: electromechanochemical forces. J Orthop Res. 1985;3(2):148-159.
2001	Smith CL. Some Aspects of the Biomechanics of Articular Cartilage Repair [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2001.
1989	Athanasiou KA. Biomechanical Assessment of Articular Cartilage Healing and Interspecies Variability [PhD thesis]. Columbia University; 1989.
1993	Setton LA. Effects of Intrinsic Viscoelasticity and Ion-Induced Swelling on the Mechanical Behavior of Articular Cartilage: Theory and Experiments [PhD thesis]. Columbia University; 1993.
1996	Iatridis JC. Biomechanics of the Anulus Fibrosus and Nucleus Pulposus of the Human Lumbar Intervertebral Disc and the Effects of Degeneration [PhD thesis]. Columbia University; 1996.
2002	Sun D. Theoretical and Experimental Investigations of the Mechano-Electrochemical Properties of Articular Cartilage, a Charged -Hydrated -Soft, Biological Tissue [PhD thesis]. Columbia University; 2002.
2007	Wan Q. Fundamental Theoretical and Experimental Studies for Applications Toward Functional Tissue Engineering of Articular Cartilage [PhD thesis]. Columbia University; 2007.
2009	Canal Guterl C. Contact Mechanics of Articular Layers: 2D Strain Fields and Their Relation to Tissue Inhomogeneity [PhD thesis]. Columbia University; 2009.
2000	Trickey WR. Mechanical Properties of Chondrocytes [PhD thesis]. Duke University; 2000.
2008	Singh M. Osteochondral Tissue Engineering for the TMJ Condyle Using a Novel Gradient Scaffold [PhD thesis]. Lawrence, KS: University of Kansas; 2008.
2016	Young WT. Cartilage Stress Relaxation Induced by Intra-Tissue Transport of Cationic Nanoparticles: Implications for Post-Traumatic Osteoarthritis Drug Delivery [Master's thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2016.
2005	Rundell SA. Investigation of the Acute Injury Response of Articular Cartilage in Vitro and in Vivo: Analysis of Various Therapeutic Treatments [Master's thesis]. East Lansing, MI: Michigan State University; 2005.
2004	Detamore MS. Characterization and Tissue Engineering of the Temporomandibular Joint Disc [PhD thesis]. Houston, TX: Rice University; July 2004.
1985	Kwan MK-W. A Finite Deformation Theory for Nonlinearly Permeable Cartilage and Other Soft Hydrated Connective Tissues and Rheological Study of Cartilage Proteoglycans [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; December 1985.
1992	Van der Voet AF. Finite Element Modelling of Load Transfer Through Articular Cartilage [PhD thesis]. Calgary, AB: University of Calgary; August 1992.
2013	Andrews S. Meniscus Structure and Function [PhD thesis]. Calgary, AB: University of Calgary; January 2013.
2007	June RK II. Polymer Dynamics as a Mechanism of Cartilage Flow-Independent Viscoelasticity [PhD thesis]. Davis, University of California; December 2007.
2010	Anderson MJ. Effects of Glycation on Dynamic Mechanical Properties and Penetration of Articular Cartilage [Master's thesis]. Davis, University of California; 2010.
1990	Wayne JS. Application of the u-p Finite Element Method to the Study of Articular Cartilage Under Small and Large Strains [PhD thesis]. San Diego (UCSD), University of California; 1990.
2000	Fedewa MM. Determinants of Microstructural Load Transfer in Cartilage Tissue from Chondrocyte Culture [PhD thesis]. University of Minnesota; August 2000.
2009	Forman J. The Structural Characteristics of the Costal Cartilage: The Roles of Calcification and the Perichondrium, and the Representation of the Costal Cartilage in Finite Element Models of the Human Body [PhD thesis]. Charlottesville, VA: University of Virginia; August 2009.
2006	Lau AG. Development of a Microstructural Homogenization Model for Calcifying Cartilage Using the Generalized Method of Cells [PhD thesis]. Charlottesville, VA: University of Virginia; January 2006.