In this thesis, a 2D finite element model was developed from patient’s DXA image to evaluate the osteoporotic fracture risk. The loading configuration was designed to simulate a fall onto the greater trochanter. Bone inhomogeneous mechanical properties (Young’s modulus) assigned to the FE model were correlated to bone mineral density captured in DXA image using empirical functions. The in-house developed MATLAB codes were implemented and used to investigate the effect of different factors like bone mineral density, femoral neck length, neck diameter, neck angle and patient’s body weight. The 2D FE model constructed from DXA image was able to determine the factors which affect fracture risk to a greater extent based on the location of femur. The model developed here can be considered as a first attempt for investigating the effects of different parameter on FRI using patient specific 2D FE method.