Measurement of mean trabecular plate thickness by a new computerized method

Garrahan, N. J.<sup>1</sup>; Mellish, R. W. E.<sup>1</sup>; Vedi, S.<sup>1</sup>; Compston, J. E.<sup>1</sup>

Affiliations

¹University of Wales College of Medicine, Heath Park, Cardiff, CF4 4XN, U.K.

Abstract and keywords

Mean trabecular plate thickness (MTPT) has been measured by a new direct computerised method on an IBAS II image analyser in iliac crest bone from 56 normal subjects. The new method has been shown to be accurate and reproducible; apart from some initial editing of the image, it is carried out automatically without any need for observer interaction. A close correlation was found between values for MTPT obtained using the new direct method and values obtained by calculation based on area and perimeter measurements made on the IBAS II (r = 0.98).

Keywords: Morphometry; Trabecular bone; Trabecular plate thickness

Links

DOI: 10.1016/8756-3282(87)90169-4

PubMed: 3446258

WoS: A1987K276200005

History

Received: 1986-10-15

Revised: 1987-03-06

Accepted: 1987-03-12

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Cited By (18)

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1988	Parisien MV, McMahon D, Pushparaj N, Dempster DW. Trabecular architecture in iliac crest bone biopsies: infra-individual variability in structural parameters and changes with age. Bone. 1988;9(5):289-295.
1990	Vesterby A. Star volume of marrow space and trabeculae in iliac crest: sampling procedure and correlation to star volume of first lumbar vertebra. Bone. 1990;11(3):149-155.
1995	Dempster DW, Birchman R, Xu R, Lindsay R, Shen V. Temporal changes in cancellous bone structure of rats immediately after ovariectomy. Bone. January 1995;16(1):157-161.
1997	Odgaard A. Three-dimensional methods for quantification of cancellous bone architecture. Bone. 1997;20(4):315-328.
1998	Müller R, Van Campenhout H, Van Damme B, Van der Perre G, Dequeker J, Hildebrand T, Rüegsegger P. Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone. July 1998;23(1):59-66.
2000	Ding M, Hvid I. Quantification of age-related changes in the structure model type and trabecular thickness of human tibial cancellous bone. Bone. March 2000;26(3):291-295.
2000	Day JS, Ding M, Odgaard A, Sumner DR, Hvid I, Weinans H. Parallel plate model for trabecular bone exhibits volume fraction-dependent bias. Bone. November 2000;27(5):715-720.
1989	Mellish RWE, Garraha NJ, Compston JE. Age-related changes in trabecular width and spacing in human iliac crest biopsies. Bone Miner. July 1989;6(3):331-338.
1989	Compston JE, Mellish RWE, Croucher P, Newcombe R, Garrahan NJ. Structural mechanisms of trabecular bone loss in man. Bone Miner. July 1989;6(3):339-350.
1988	Bergot C, Laval-Jeantet A-M, Prêteux F, Meunier A. Measurement of anisotropic vertebral trabecular bone loss during aging by quantitative image analysis. Calcif Tiss Int. September 1988;43(3):143-149.
1989	Croucher PI, Mellish RWE, Vedi S, Garrahan NJ, Compston JE. The relationship between resorption depth and mean interstitial bone thickness: age-related changes in man. Calcif Tiss Int. July 1989;45(1):15-19.
1991	Mellish RWE, Ferguson‐Pell MW, Cochran GVB, Lindsay R, Dempster DW. A new manual method for assessing two‐dimensional cancellous bone structure: comparison between iliac crest and lumbar vertebra. J Bone Miner Res. July 1991;6(7):689-696.
1997	Hildebrand T, Rüegsegger P. A new method for the model-independent assessment of thickness in three-dimensional images. J Microsc (Oxford). 1997;185(1):67-75.
1997	Zou L, Bloebaum RD, Bachus KN. Reproducibility of techniques using Archimedes' principle in measuring cancellous bone volume. Med Eng Phys. January 1997;19(1):63-68.
2005	Day JS. Bone Quality: The Mechanical Effects of Microarchitecture and Matrix Properties [PhD thesis]. Erasmus University Rotterdam; 2005.
2002	Follet H. Caractérisation Biomécanique Et Modélisation 3D Par Imagerie X Et IRM Haute Résolution De L’os Spongieux Humain: Evaluation Du Risque Fracturaire [PhD thesis]. Institut national des sciences appliquées de Lyon (INSA Lyon); 2002.
2010	Rami E. Automated Design of Trabecular Structures [PhD thesis]. Loughborough, UK: Loughborough University; February 2010.
2006	Lau AG. Development of a Microstructural Homogenization Model for Calcifying Cartilage Using the Generalized Method of Cells [PhD thesis]. Charlottesville, VA: University of Virginia; January 2006.