Software is being developed under a US Department of Transportation Small Business Innovative Research Program that predicts occupant dynamics, kinematics, and contacts with vehicle interior surfaces in real world crashes. The software is being developed as a tool for medical, engineering, and crash investigators to better understand the biomechanics of crash injuries, simplify the reconstruction of injury mechanisms, and provide insight into potential injury mechanisms, injury prevention, and injury treatment. The software is intended to be a high capacity, economical, and easy to use bridge between accident databases and biomechanics and injury models. The software is based in part on a newly developed Graphics User Interface (GUI), an enhanced version of the US Air Force Articulated Total Body (ATB) multi-body crash simulation program, an extended version of the USAF Generator of Body Data (GEBOD) human modeling program, and DRI’s VisionForm 3D animation program used to visualize occupant and vehicle kinematics. In the Phase I proof-of-concept software, data for the vehicle, occupant, multi-stage 3D crash pulses, observed interior contacts and observed injuries can be downloaded from the CIREN accident database or by manual input. The Phase I software then provides for the automatic nominal positioning of the occupant and seat belt system in the vehicle, and subsequent simulation of the crash event. The user can then view animations of the resulting occupant and vehicle motions, and review a summary of the predicted occupant/vehicle contacts and contact forces. In Phase I, proof- of-concept software that provides basic functionality was successfully developed. It is anticipated that development to further extend its capabilities will result in a low-cost, commercially viable, easy-to-use software package that will aid crash investigators and safety researchers in further understanding the dynamics, kinematics, forces, and injuries associated with real world accidents.