Head-on collisions are simulated on the impact sled with different instrument panels and unembalmed, nonbelted cadavers. The accelerations above the crown of the head and at the back at the level of the middle of the chest are measured and all injuries ascertained by autopsy. The results give constructional ideas for the design of the instrument panel on the passenger side. To avoid injuries to the trunk and legs, the impact areas for the trunk and for the knees should be so placed as to enable the trunk to retain its almost upright position on impact. The impact area for the trunk should be as large as possible and not fold out upward. The avoidance of head and neck injuries presents a particularly difficult problem.