Recently a cartilage growth finite element model (CGFEM) was developed to predict cartilage biomechanical properties after time-dependent growth [1, 2]. The goal of the current work was to continue development of the CGFEM by (1) implementing the new collagen constituent equations, (2) creating analyses to simulate fluid-permeation experimental protocol, and (3) predicting results for different eases of growth. The collagen equation was successfully implemented and a Jacobian matrix was derived that out performed a push-forward approximation. The protocol was implemented through the alternating interaction of the two primary CGFEM components (FEA and element growth routine). Preliminary results obtained while implementing the protocol suggested that fluid diffusive velocities in excess of 0.5μm/s caused extremely high strains and the experimental protocol was modified accordingly. Results for the fluid permeation simulations indicated that it would be difficult to detect collagen growth in the actual experiments. The predicted results, however. show a marked increase in proteoglycan mass for both 6 and 12 days of growth. The modified CGFEM served as flexible analysis tool capable of guiding experimental protocols and predicting growth results.