The use of biochemical markers of bone turnover in osteoporosis

Delmas, P. D.<sup>1</sup>; Eastell, R.<sup>2</sup>; Garnero, P.<sup>3</sup>; Seibel, M. J.<sup>4</sup>; Stepan, J.<sup>5</sup>

Affiliations

¹Inserm Research Unit 403 and Claude Bernard University of Lyon, France

²Bone Metabolism Group, University of Sheffield, UK

³Inserm Research Unit 403 and Synarc, France

⁴Department of Medicine, University of Heidelberg, Germany

⁵Department of Internal Medicine 3, Charles University Faculty of Medicine, Czech Republic

Keywords

Keywords: Osteoporosis; Bone Turnover; Biochemical Marker

Links

DOI: 10.1007/s001980070002

WoS: 000166194200002

Cited Works (7)

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1996	Garnero P, Hausherr E, Chapuy M, Marcelli C, Grandjean H, Muller C, Cormier C, Bréart G, Meunier PJ, Delmas PD. Markers of bone resorption predict hip fracture in elderly women: the EPIDOS prospective study. J Bone Miner Res. October 1996;11(10):1531-1538.
1996	Riggs BL, Melton LJ III, O'Fallon WM. Drug therapy for vertebral fractures in osteoporosis: evidence that decreases in bone turnover and increases in bone mass both determine antifracture efficacy. Bone. March 1996;18(3)(suppl 1):197S-201S.
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1996	Garnero P, Sornay‐Rendu E, Chapuy M, Delmas PD. Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res. 1996;11(3):337-349.
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2000	Garner P, Sornay-Rendu E, Claustrat B, Delmas PD. Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study. J Bone Miner Res. August 2000;15(8):1526-1536.

Cited By (23)

Year	Entry
2004	Kanis J, Johnell O, De Laet C, Johansson H, Oden A, Delmas P, Eisman J, Fujiwara S, Garnero P, Kroger H, McCloskey E, Mellstrom D, Melton L, Pols H, Reeve J, Silman A, Tenenhouse A. A meta-analysis of previous fracture and subsequent fracture risk. Bone. August 2004;35(2):375-382.
2009	Kanis JA, Oden A, Johansson H, Borgström F, Ström O, McCloskey E. FRAX^® and its applications to clinical practice. Bone. May 2009;44(5):734-743.
2021	Smith C, Tacey A, Mesinovic J, Scott D, Lin X, Brennan-Speranza TC, Lewis JR, Duque G, Levinger I. The effects of acute exercise on bone turnover markers in middle-aged and older adults: a systematic review. Bone. February 2021;143:115766.
2021	Iki M, Yura A, Fujita Y, Kouda K, Tamaki J, Tachiki T, Kajita E, Iwaki H, Ishizuka R, Moon J-S, Okamoto N, Kurumatani N. Circulating osteocalcin levels were not significantly associated with the risk of incident type 2 diabetes mellitus in elderly Japanese men: the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Cohort Study. Bone. June 2021;147:115912.
2022	Smith C, Hiam D, Tacey A, Lin X, Woessner MN, Zarekookandeh N, Garnham A, Chubb P, Lewis JR, Sim M, Herrmann M, Duque G, Levinger I. Higher bone remodeling biomarkers are related to a higher muscle function in older adults: effects of acute exercise. Bone. December 2022;165:116545.
2023	Guan Z, Yuan W, Jia J, Zhang C, Zhu J, Huang J, Zhang W, Fan D, Leng H, Li Z, Xu Y, Song C. Bone mass loss in chronic heart failure is associated with sympathetic nerve activation. Bone. January 2023;166:116596.
2005	Felsenberg D, Boonen S. The bone quality framework: determinants of bone strength and their interrelationships, and implications for osteoporosis management. Clin Ther. January 2005;27(1):1-11.
2003	Eastell R, Barton I, Hannon R, Chines A, Garnero P, Delmas P. Relationship of early changes in bone resorption to the reduction in fracture risk with risedronate. J Bone Miner Res. June 2003;18(6):1051-1056.
2005	Sornay-Rendu E, Munoz F, Garnero P, Duboeuf F, Delmas PD. Identification of osteopenic women at high risk of fracture: the OFELY study. J Bone Miner Res. October 2005;20(10):1813-1819.
2006	Szulc P, Seeman E, Duboeuf F, Sornay-Rendu E, Delmas PD. Bone fragility: failure of periosteal apposition to compensate for increased endocortical resorption in postmenopausal women. J Bone Miner Res. December 2006;21(12):1856-1863.
2021	Smith C, Lewis JR, Sim M, Lim WH, Lim EM, Blekkenhorst LC, Brennan‐Speranza TC, Adams L, Byrnes E, Duque G, Levinger I, Prince RL. Higher undercarboxylated to total osteocalcin ratio is associated with reduced physical function and increased 15‐year falls‐related hospitalizations: the Perth Longitudinal Study of Aging Women. J Bone Miner Res. March 2021;36(3):523-530.
2020	Hart NH, Newton RU, Tan2 J, Rantalainen T, Chivers P, Siafarikas A, Nimphius S. Biological basis of bone strength: anatomy, physiology and measurement. J Musculoskel Neuron Interact. September 2020;20(3):347-371.
2002	Delmas PD. Treatment of postmenopausal osteoporosis. Lancet. June 8, 2002;359(9322):2018-2026.
2003	Bouxsein ML. Bone quality: where do we go from here? Osteoporos Int. September 2003;14(suppl 5):S118-S127.
2005	Kanis JA, Johansson H, Johnell O, Oden A, De Laet C, Eisman JA, Pols H, Tenenhouse A. Alcohol intake as a risk factor for fracture. Osteoporos Int. July 2005;16(7):737-742.
2011	Vasikaran S, Eastell R, Bruyère O, Foldes AJ, Garnero P, Griesmacher A, McClung M, Morris HA, Silverman S, Trenti T, Wahl DA, Cooper C, Kanis JA; OF-IFCC Bone Marker Standards Working Group. Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards. Osteoporos Int. February 2011;22(2):391-420.
2013	Kanis JA, McCloskey EV, Johansson H, Cooper C, Rizzoli R, Reginster J-Y; Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO); Committee of Scientific Advisors of the International Osteoporosis Foundation (IOF). European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int. January 2013;24(1):23-57.
2019	Kanis JA, Cooper C, Rizzoli R, Reginster J-Y; Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO); Committees of Scientific Advisors and National Societies of the International Osteoporosis Foundation (IOF). European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int. January 2019;30(1):3-44.
2017	Billington E. Emerging Issues in Osteoporosis [MD thesis]. Auckland, New Zealand: University of Auckland; 2017.
2017	Owen R. Tissue Engineering an in Vitro Model of Osteoporosis [PhD thesis]. Sheffield, UK: University of Sheffield; October 2017.
2005	Squire ME. Bone’s Response to Unloading, as Defined by Altered Gene Expression, Cellular Activity, and Architecture, is Modulated by Genetics and Gender [PhD thesis]. Stony Brook, NY: Stony Brook University; August 2005.
2011	Lam MCW. Single Chain Fraction Variable Binding Molecules as Bone-Targeting Therapeutics and Diagnostics [Master's thesis]. Edmonton, AB: University of Alberta; 2011.
2023	Austermann K. Effects of Nutritive Antioxidants on Bone During Immobility [PhD thesis]. Rheinische Friedrich-Wilhelms-Universität Bonn; 2023.