Effect of cyclic and static tensile loading on water content and solute diffusion in canine flexor tendons:​ an in vitro study

Hannafin, Jo A.<sup>1</sup>; Arnoczky, Steven P.<sup>1</sup>

Affiliations

¹Laboratory for Comparative Orthopaedic Research, The Hospital for Special Surgery, Affiliated with New York Hospital-Cornell University Medical Center, New York, New York, U.S.A.

Abstract

This study was designed to determine the effects of various loading conditions (no load and static and cyclic tensile load) on the water content and pattern of nutrient diffusion of canine flexor tendons in vitro. Region D (designated by Okuda et al.) of the flexor digitorum profundus was subjected to a cyclic or static tensile load of 100 g for times ranging from 5 minutes to 24 hours. The results demonstrated a statistically significant loss of water in tendons subjected to both types of load as compared with the controls (no load). This loss appeared to progress with time. However, neither static nor cyclic loading appeared to alter the diffusion of ³H-glucose into the tendon over a 24-hour period compared with the controls. These results suggest that any benefit in tendon repair derived from intermittent passive motion is probably not a result of an increase in the diffusion of small nutrients in response to intermittent tensile load.

Links

DOI: 10.1002/jor.1100120307

PubMed: 8207588

WoS: A1994NQ51700006

History

Received: 1992-07-28

Accepted: 1993-07-16

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Cited By (28)

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2019	Naghizadeh Safa B. Analysis and Modeling of Inelasticity in Tendon: Viscoelasticity, Damage, and Plastic Deformation [PhD thesis]. University of Delaware; 2019.
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2015	Szczesny SE. Analysis of the Contribution of Interfibrillar Sliding on Tendon Fascicle Multiscale Mechanics [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2015.
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2002	Gardiner JC. Computational Modeling of Ligament Mechanics [PhD thesis]. University of Utah; May 2002.
2012	Ellis BJ. Finite Element Modeling of Knee and Shoulder Ligaments [PhD thesis]. University of Utah; May 2012.
2012	Reese SP. Multiscale Structure-Function Relationships in the Mechanical Behavior of Tendon and Ligament [PhD thesis]. University of Utah; May 2012.
2014	Swedberg A. Continuum Description of the Time- and Strain-Dependent Poisson's Ratio of Ligament Under Finite Deformation [Master's thesis]. University of Utah; May 2014.
2011	Duenwald-Kuehl S. Characterization of Tendon Mechanics: Experiment, Modeling, and Noninvasive Methods [PhD thesis]. University of Wisconsin – Madison; 2011.
2020	King NO. Biomedical Applications of Polarimetry [PhD thesis]. St. Louis, MO: Washington University in St. Louis; August 2020.