This paper shows the effect of the roof contact angle with ground and pitch/yaw angle on head and neck injuries in CRIS tests. In this study the effect of these conditions on injury in a rollover is simulated and analyzed by using a commercial multi-body software (ADAMS). The vehicle model consists of a rigid lower body and deformable upper body. Each member of the upper body is characterized to get the similar behavior to the results obtained from an equivalent finite element model. To evaluate the severity of driver’s injuries in a CRIS test, a computer simulation to replicate the dynamic CRIS test is developed. The angular velocity of vehicle is set to a constant value of 270 degree/sec and the lateral velocity is varied to be 28.8kph or 35kph so that it can roll 2 or 3 turns. The roof contact angle with ground is selected to be 135, 145 and 155 degrees. The pitch and yaw angles of the vehicle is also varied to be 2 or 5 degrees and 0, 10, or 20 degrees, respectively. In addition to the peak acceleration of the dummy head, the maximum shear force, compressive force, and bending moment acting on the dummy neck are calculated to evaluate the rollover safety for various conditions. The simulation results are then compared to the KNCAP evaluation criteria. Considering the fact that the rollover accidents with less than 2 full turns account for about 90% of the entire rollover accidents, this study suggests that the 2-turn condition would be appropriate for a protocol of the dynamic rollover test.