A computational study of thorax interaction with seat belt restraint was performed using a human thorax finite element model. The model consists of the rib cage, chest wall, internal organs, diaphragm and upper abdomen. Simulation was performed to validate the model against selected cadaver data from seat belt loading tests conducted by Cesari and Bouquet (1990) with good chest deformation data agreement. A series of crash simulations was performed for a 3-point belt system with reasonable results obtained showing increase of chest deformation and internal organ stress with crash velocity. The results show that the model is capable of undergoing long-duration deformation engagement with seat belt loads. Limitations of the model are recognized with recommendations given.