Replacement of the human shoulder with implants is a commonly employed procedure in orthopedics to alleviate patient discomfort and pain. The alignment of the implant relative to bone is an important parameter when considering the stability and long-term fixation of the implant. This thesis explored the effect of the selection of the cut plain by 4 different surgeons in a series of glenoid models, and subsequently evaluated the variation of the cut planes on load transfer from implant to bone using finite element modeling. The findings indicated that there is a wide variation in the selection of the cut plane amongst the surgeons based on a target alignment established via preoperative planning software. Using the variation that was determined in this study, it was shown that the stresses and implant stability or micromotion were highly variable for these various different combinations of cut planes. It is concluded that with current approaches to the selection of cut planes, there is a wide variation in the load transfer mechanics, even for the same bone model. This has implications with regard to surgical outcomes and biomechanical modelling predictions.