Central sensitization (CSens) is a pain mechanism marked by hypersensitivity to stimuli. It is believed that neuroplastic changes caused by increased nociceptive input may allow sensory information to affect motor pathways. This study investigated the relationship between CSens and muscle function. Fifteen healthy participants underwent two interventions where capsaicin either induced CSens or was blocked with lidocaine. Three measurements were taken from the soleus and tibialis anterior muscles:​ shear wave elastography to monitor changes in muscle stiffness;​ surface electromyography to measure motor unit recruitment order, and F-wave amplitude and persistence to measure motor neuron excitability;​ torque recordings to determine force steadiness. An increase in the stiffness of the tibialis anterior was observed following the application of capsaicin. The amplitude and persistence of the F-waves were not significantly different after either intervention. Furthermore, although there was a change in motor unit recruitment, force steadiness did not change during the torque recordings.