Types I and II collagens in intervertebral disc:​ interchanging radial distributions in annulus fibrosus

Eyre, David R.; Muir, Helen

Affiliations

¹Biochemistry Division, Kennedy Institute of Rheumatology, Bute Gardens, Hammersmith, London W6 7DW, U.K.

Abstract

Intervertebral disc is a highly specialized cartilaginous tissue, containing two genetic types of collagen (I and II). Analysis of peptides from a CNBr digest of collagen showed that the proportions of I and II varied gradually and inversely across pig annulus fibrosus, with exclusively type I at the extreme outer edge and exclusively type II in the nucleus pulposus.

Links

DOI: 10.1042/bj1570267

PubMed: 962859

History

Received: 1976-04-12

Cited By (34)

Year	Entry
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