There is a mean incidence of osteoarthritis (OA) of the hip in 8% of the overall population. In the presence of focal chondral defects, defined as localized damage to the articular cartilage, there is an increased risk of symptomatic progression toward OA. This relationship between chondral defects and subsequent development of OA has led to substantial efforts to develop effective procedures for surgical cartilage repair. This study examined the effects of chondral defects and labral delamination on cartilage mechanics in the dysplastic hip during the gait cycle using patient-specific finite element (FE) analysis. Models were generated from volumetric CT data and analyzed with simulated chondral defects at the chondrolabral junction on the posterior acetabulum at five distinct points in the gait cycle. Defects increased maximum shear stress on the osteochondral surface of the acetabular cartilage, compared to the intact case. This effect was amplified with labral delamination. Defects increased first principal Lagrange strain on the articular surface of the acetabular cartilage and labrum. Labral delamination relieved some of this tensile strain. As defect size increased, contact stress increased medially in the acetabulum, while it decreased anteriorly. The results suggest that in the presence of chondral defects and labral delamination, the cartilage experiences elevated tensile strains and shear and contact stresses, which could lead to further damage of the cartilage, and subsequent arthritic progression. The framework presented here will be used in future FE studies on cartilage mechanics in hips with varying disease states presenting chondral defects and labral tears.