1MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK
2Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
3NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK
4British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
5National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK
6British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK
7Department of Brain Sciences and UK Dementia Research Institute Centre, Imperial College London, London, UK
8Musculoskeletal Research Unit, University of Bristol, Bristol, UK
9Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK
10Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK
11Department of Human Genetics, Wellcome Sanger Institute, Hinxton, UK
12National Institute for Health and Care Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK
13National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, UK