This thesis sought to develop a model to emulate coronary balloon-stent angioplasty. A model predictive of the radial expansion experienced by a balloon-stent-vessel system under internal pressure was developed. Seven parametric stent configurations modeled after the Boston Scientific TAXUStm Express2tm stent were generated in Pro/Engineer 4.0 which varied in strut cross section. These stents were expanded using finite element package ABAQUS/CAE 6.7 under non-linear, large deformation conditions. An elasto-plastic, Ramberg-Osgood material model for 316L stainless steel with two different work hardening exponents was used. Radial expansion vs. internal pressure data was collected in each simulation. The blood vessel expansion behavior was analytically developed using a hyperelastic model borrowed from existing literature. An area fraction model was used to assess the load transfer from the balloon external surface to the stent inner surface. The balloon, stent, and vessel models were combined and favorably compared to the manufacturing data that accompanied the TAXUS stent. It was found that stent strut cross section and material work hardening greatly affected the radial expansion-pressure curves. Balloon effects were found to be prominent and increased in severity as the stent unfolded. Vessel behavior was found to be relatively compliant compared to the stent, but with the inclusion of atherosclerotic plaque the simple rule of mixtures showed that the effective shear modulus of the vessel stiffened significantly. These results verify the feasibility of generating an accurate predictive model of balloon-stent-vessel expansion and serve as the foundation for future modeling.