The present study was conducted with the car driven at speed of 60 and 80 [km/h]. The purpose of the study was to investigate the effect of different seating conditions and different speed on the vibration transmitted through the seat pan, in all directions, to the seated human body. The vibration dose value was measured on the seat along x-, y- and z- directions. It is proposed an integrating finite element method and multi-body simulation for seated human body. The analysis of power spectrum density shows how the vehicle seats should have the capability of attenuating the vibration at frequencies coinciding with the resonance frequencies of the human body to avoid discomfort or health problems due to vibration.