Nowadays, more and more people pay attention to the safety and health of human body under strong vibration. Quantifying the level of anxiety under vibration is valuable for clarifying the structural performance needed for human safety and will facilitate the communication between structural designers and clients about comfort. Chiba University has been devoting itself to the study of the anxiety of human-body induced by earthquake vibration since 2000, and has preliminarily obtained a curve to describe the Anxiety quantitatively. It is defined as "Anxiety curve of Human Body under Vibration"(AHV). In this study, a shaking-table test for humans who are wearing a head-mounted display (HMD) was performed to quantify the levels of anxiety during strong vibration. A virtual scene consisting of a living room with several pieces of furniture was simulated using virtual reality (VR). The period, speed, and shape of input vibration were varied for each VR-based situation. The results of the test show that a longer shaking period produced lower levels of anxiety. The results of this study will further advance our understanding about how vibration in a building affects the anxiety of its occupants during strong vibration.