The evolutionary healing phenomenon of fractured tibia bone was investigated by comparing the bio-mechanical response of the human tibia following fracture fixation for two ranges of patient ages, when a body weight pressure (BWP) is applied. Three-dimensional finite element models have been developed by adopting the biomechanical characteristics of cortical and trabecular tibia bones, and considering the time-varying callus properties during the healing process for the two patients. The stress and strain levels generated within the fractured tibia bone by the screw tight fit during the assembly process revealed its dependence on the bone stiffness that degrades with age. They have an impact on primary stability of the implants prior to the osseointegration. The gap capacity to resist and allow a gradual BWP load transfer, through the callus for the tibia bone models, was analyzed. In fact, from 10 weeks after surgery, the callus allowed the BWP transfer for young patients, which guarantees sufficient structure stabilization of the fractured tibia. However, an insufficient load was transferred to the fracture gap for the old patient, even beyond 16 weeks, which delayed the bone consolidation