1Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK
2Edinburgh Orthopaedic Trauma, Royal Infirmary of Edinburgh, Edinburgh, UK
3Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
4Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK
5Trauma and Orthopaedic Surgery, University of Manchester, Manchester, UK
6Oxford University Hospitals NHS Foundation Trust, Headington, UK
7The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
8Norfolk and Norwich University Hospital Foundation Trust, Norwich, UK
9Ipswich Hospital NHS Trust, Ipswich, UK
10Royal London Hospital, Barts Health NHS Trust, London, UK
11Royal Berkshire Hospital Foundation Trust, Reading, UK
12NHS Ayrshire and Arran, Ayr, UK
13Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
14Warrington and Halton Hospitals NHS Foundation Trust, Warrington, UK
15Queen's Hospital, Romford, UK
16Raigmore Hospital, Inverness, UK
17South Tees, Hospitals NHS Foundation Trust, Middlesbrough, UK
18Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK