Ankle injuries are the most common among the sports injuries, of which ankle sprains and recurrent ankle sprains are more frequent. This chapter discusses various aetiology and the pathomechanical factors responsible for the ankle sprain, grading of ankle sprains and their management at all the stages of recovery till the return to sports or competition. Long term follow up studies have demonstrated, functional treatment superior to surgical repair. The criteria in progressing to each stage is very crucial and is tabulated at each phases of tissue healing. Functional progression of early mobilisation with external ankle support is emphasised throughout the chapter. As chronic ankle instability is important sequelae of acute ankle injury, the preventive program is described to the end of the chapter.