We investigated the effects of speed cameras along a 26 mile segment in metropolitan Phoenix, Arizona. Motor vehicle collisions were retrospectively identified according to three time periods – before cameras were placed, while cameras were in place and after cameras were removed. A 14 mile segment in the same area without cameras was used for control purposes. Five cofounding variables were eliminated. In this study, the placement or removal of interstate highway speed cameras did not independently affect the incidence of motor vehicle collisions