A study was conducted to examine the relationship between sleep quality and how commercial drivers balanced conflict when the need to rest interfered with their ability to maintain tight delivery schedules. Face-to-face interviews were conducted with 188 commercial drivers to collect physiological data and self-reported measures. Multivariate linear regression models were developed to analyze relationships between sleep quantity, sleep quality, symptoms of obstructive sleep apnea, and how schedule-based priorities were established. A significant correlation was found between sleep quality and how preference was given by commercial drivers, when symptoms of fatigue were detected, to balance conflict between the need to rest and the real or perceived duty to comply with externally-imposed schedule demands.