Multiscale aspects of mechanical properties of biological materials

Buehler, Markus J.

Affiliations

¹Laboratory for Atomistic and Molecular Mechanics, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave. Room 1-235A&B, Cambridge, MA, USA

²Center for Computational Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA, USA

³Center for Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA, USA

Abstract

Multiscale aspects of mechanical properties of biological materials have developed into an emerging area of research with impact in a broad range of disciplines ranging from medicine to materials science, defining a biomateriomics approach that facilitates a new paradigm in understanding the interplay of structure and function. Mechanical properties of biological materials are critical for virtually all physiological processes and cover all the scales, from the molecular to the macroscale, and provide access to mechanistic understanding and engineering design of novel tools for disease diagnosis, disease treatment and biomaterials development or for the transfer of biologically inspired materials and structures. The integrated use of simulation and experiment can address key challenges in this field and will result in new tools for the analysis and synthesis of complex materials.

Links

DOI: 10.1016/j.jmbbm.2010.12.018

PubMed: 21262489

WoS: 000287560500001

Cited By (1)

Year	Entry
2011	Barth HD, Zimmermann EA, Schaible E, Tang SY, Alliston T, Ritchie RO. Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone. Biomaterials. December 2011;32(34):8892-8904.