Processing of undecalcified bone specimens for bone histomorphometry

Baron, Roland<sup>1</sup>; Vignery, Agnes<sup>1</sup>; Neff, Lynn<sup>1</sup>; Silvergate, Ann<sup>1</sup>; Santa Maria, Angelica<sup>1</sup>

Year	Entry
1984	Baron R, Tross R, Vignery A. Evidence of sequential remodeling in rat trabecular bone: morphology, dynamic histomorphometry, and changes during skeletal maturation. Anat Rec. January 1984;208B(1):137-145.
1986	Wronski TJ, Walsh CC, Ignaszewski LA. Histologic evidence for osteopenia and increased bone turnover in ovariectomized rats. Bone. 1986;7(2):119-123.
1989	Weinreb M, Rodan GA, Thompson DD. Osteopenia in the immobilized rat hind limb is associated with increased bone resorption and decreased bone formation. Bone. 1989;10(3):187-194.
1989	Wronski TJ, Dann LM, Horner SL. Time course of vertebral osteopenia in ovariectomized rats. Bone. 1989;10(4):295-301.
1997	Mosley JR, March BM, Lynch J, Lanyon LE. Strain magnitude related changes in whole bone architecture in growing rats. Bone. March 1997;20(3):191-198.
1998	Mosley JR, Lanyon LE. Strain rate as a controlling influence on adaptive modeling in response to dynamic loading of the ulna in growing male rats. Bone. October 1998;23(4):313-318.
1999	Wronski TJ, Pun S, Liang H. Effects of age, estrogen depletion, and parathyroid hormone treatment on vertebral cancellous wall width in female rats. Bone. October 1999;25(4):465-468.
2002	Lee KCL, Maxwell A, Lanyon LE. Validation of a technique for studying functional adaptation of the mouse ulna in response to mechanical loading. Bone. September 2002;31(3):407-412.
2005	De Souza RL, Matsuura M, Eckstein F, Rawlinson SCF, Lanyon LE, Pitsillides AA. Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: a new model to study cortical and cancellous compartments in a single loaded element. Bone. December 2005;37(6):810-818.
2008	Sugiyama T, Saxon LK, Zaman G, Moustafa A, Sunters A, Price JS, Lanyon LE. Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1–34) on trabecular and cortical bone in mice. Bone. August 2008;43(2):238-248.
2010	Sugiyama T, Price JS, Lanyon LE. Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones. Bone. February 2010;46(2):314-321.
1985	Wronski TJ, Lowry PL, Walsh CC, Ignaszewski LA. Skeletal alterations in ovariectomized rats. Calcif Tiss Int. May 1985;37(3):324-328.
1988	Wronski TJ, Cintrón M, Dann LM. Temporal relationship between bone loss and increased bone turnover in ovariectomized rats. Calcif Tiss Int. September 1988;43(3):179-183.
1989	Wronski TJ, Dann LM, Scott KS, Cintrón M. Long-term effects of ovariectomy and aging on the rat skeleton. Calcif Tiss Int. December 1989;45(6):360-366.
1992	Rubin CT, Bain SD, McLeod KJ. Suppression of the osteogenic response in the aging skeleton. Calcif Tiss Int. April 1992;50(4):306-313.
1993	Recker RR. Architecture and vertebral fracture. Calcif Tiss Int. 1993;53(suppl 1):S139-S142.
1994	Torrance AG, Mosley JR, Suswillo RFL, Lanyon LE. Noninvasive loading of the rat ulna in vivo induces a strain-related modeling response uncomplicated by trauma or periostal pressure. Calcif Tiss Int. March 1994;54(3):241-247.
1998	Akhter MP, Cullen DM, Pedersen EA, Kimmel DB, Recker RR. Bone response to in vivo mechanical loading in two breeds of mice. Calcif Tiss Int. November 1998;63(5):442-449.
2000	Akhter MP, Iwaniec UT, Covey MA, Cullen DM, Kimmel DB, Recker RR. Genetic variations in bone density, histomorphometry, and strength in mice. Calcif Tiss Int. October 2000;67(4):337-344.
1988	Wronski TJ, Cintron M, Doherty AL, Dann LM. Estrogen treatment prevents osteopenia and depresses bone turnover in ovariectomized rats. Endocrinology. August 1988;123(2):681-686.
1993	Engelke K, Graeff W, Meiss L, Hahn M, Delling G. High spatial resolution imaging of bone mineral using computed microtomography: comparison with microradiography and undecalcified histologic sections. Invest Radiol. April 1993;28(4):341-349.
1988	Recker RR, Kimmel DB, Parfitt MA, Davies MK, Keshawarz N, Hinders S. Static and tetracycline‐based bone histomorphometric data from 34 normal postmenopausal females. J Bone Miner Res. April 1988;3(2):133-344.
1998	Lane NE, Thompson JM, Haupt D, Kimmel DB, Modin G, Kinney JH. Acute changes in trabecular bone connectivity and osteoclast activity in the ovariectomized rat in vivo. J Bone Miner Res. February 1998;13(2):229-236.
2004	Recker R, Lappe J, Davies KM, Heaney R. Bone remodeling increases substantially in the years after menopause and remains increased in older osteoporosis patients. J Bone Miner Res. October 2004;19(10):1628-1633.
2010	Brodt MD, Silva MJ. Aged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression. J Bone Miner Res. September 2010;25(9):2006-2015.
1993	Balena R, Toolan BC, Shea M, Markatos A, Myers ER, Lee SC, Opas EE, Seedor JG, Klein H, Frankenfield D, Quartuccio H, Fioravanti C, Clair J, Brown E, Hayes WC, Rodan GA. The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates. J Clin Invest. December 1993;92(6):2577-2586.
1986	Villanueva AR, Sypitkowski C, Parfitt AM. A new method for identification of cement lines in undecalcified, plastic embedded sections of bone. Stain Tech. March 1986;61(2):83-88.
1990	Bain SD, Impeduglia TM, Rubin CT. Cement line staining in undecalcified thin sections of cortical bone. Stain Tech. 1990;65(4):159-163.
2006	Warden KE. Localized Trabecular Damage Adjacent to Interbody Fusion Devices [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2006.
2009	Slyfield CR Jr. Automated Sub-Micron Resolution Serial Block Face Imaging of Cancellous Bone Using Epifluorescence Microscopy [Master's thesis]. Cleveland, OH: Case Western Reserve University; January 2009.
2012	Slyfield CR Jr. The Biomechanics of Bone Turnover [PhD thesis]. Ithaca, NY: Cornell University; January 2012.
2021	Al Hamed FSM. Role of Plasma Composition on Bone Healing and Implant Osseointegration [PhD thesis]. McGill University; March 2021.
1992	Bloomfield SA. Site-Specific Changes in Bone Mass and Alterations in Calciotropic Hormones With Electrical Stimulation Exercise in Individuals With Chronic Spinal Cord Injury [PhD thesis]. The Ohio State University; 1992.
2016	Heffner MA. Bone Adaptation in a Mouse Model of Reduced Sensory Nerve Function [PhD thesis]. Davis, University of California; 2016.
2012	Bassit ACF. Role of IGF-I as a Potential Mediator for the Skeletal Effects of Bone Anabolic Agents [PhD thesis]. University of Florida; August 2012.
2016	Takyar F. Osteoblastic EphrinB2 in Normal and Parathyroid Hormone (PTH)-Stimulated Bone Formation [PhD thesis]. University of Melbourne; June 2016.
2016	Vrahna C. Investigating the Effects of Downstream Parathyroid Hormone (PTH) Targets on Bone Strength and Quality [PhD thesis]. Melbourne, Australia: The University of Melbourne; December 2016.
1996	Beck BR. The Relationship of Streaming Potential Magnitude to Strain and Periosteal Modeling [PhD thesis]. Eugene, OR: University of Oregon; December 1996.
2007	Christiansen BA. Vibrational Stimulation of Bone Formation in Mice [PhD thesis]. St. Louis, MO: Washington University in St. Louis; December 2007.