The effect of continuous mechanical pressure upon the turnover of articular cartilage proteoglycans in vitro

Jones, Ian L.<sup>1</sup>; Klämfeldt, Agneta<sup>1</sup>; Sandström, Torsten<sup>1</sup>

Year	Entry
1994	Mow VC, Bachrach NM, Setton LA, Guilak F. Stress, strain, pressure and flow fields in articular cartilage and chondrocytes. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:345-379.
1994	Guilak F, Donahue HJ, Zell RA, Grande D, McLeod KJ, Rubin CT. Deformation-induced calcium signaling in articular chondrocytes. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:380-397.
1994	Urban JPG, Hall AC. The effects of hydrostatic and osmotic pressures on chondrocyte metabolism. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:398-419.
1997	Ishihara H, Warensjo K, Roberts S, Urban JPG. Proteoglycan synthesis in the intervertebral disk nucleus: the role of extracellular osmolality. Am J Physiol Cell Physiol. May 1997;272(5):C1499-C1506.
2004	Hung CT, Mauck RL, Wang CC-B, Lima EG, Ateshian GA. A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading. Ann Biomed Eng. January 2004;32(1):35-49.
2000	Grodzinsky AJ, Levenston ME, Jin M, Frank EH. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng. 2000;2:691-713.
1984	Palmoski MJ, Brandt KD. Effects of static and cyclic compressive loading on articular cartilage plugs in vitro. Arthritis Rheum. June 1984;27(6):675-681.
1999	Carver SE, Heath CA. Increasing extracellular matrix production in regenerating cartilage with intermittent physiological pressure. Biotechnol Bioeng. 1999;62(2):166-174.
1994	Urban JPG. The chondrocyte: a cell under pressure. Br J Rheumatol. October 1994;33(10):901-908.
1995	Lee DA, Bader DL. The development and characterization of anin vitro system to study strain-induced cell deformation in isolated chondrocytes. In Vitro Cell Dev Biol Anim. December 1995;31(11):828-835.
1996	Ishihara H, McNally DS, Urban JP, Hall AC. Effects of hydrostatic pressure on matrix synthesis in different regions of the intervertebral disk. J Appl Physiol. March 1996;80(3):839-846.
1991	Burger EH, Klein-Nulend J, Veldhuuzen JP. Modulation of osteogenesis in fetal bone rudiments by mechanical stress in vitro. J Biomech. 1991;24(suppl 1):101-109.
1997	Torzilli PA, Grigiene R, Huang C, Friedman SM, Doty SB, Boskey AL, Lust G. Characterization of cartilage metabolic response to static and dynamic stress using a mechanical explant test system. J Biomech. January 1997;30(1):1-9.
2024	Rich MJ, Burnash S, Krishnan RR, Chubinskaya S, Loeser RF, Polacheck WJ, Diekman BO. Use of a novel magnetically actuated compression system to study the temporal dynamics of axial and lateral strain in human osteochondral plugs. J Biomech. January 2024;162:111887.
2000	Mauck RL, Soltz MA, Wang CCB, Wong DD, Chao P-HG, Valhmu WB, Hung CT, Ateshian GA. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng. June 2000;122(3):252-260.
1993	Urban JPG, Hall AC, Gehl KA. Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes. J Cell Physiol. February 1993;154(2):262-270.
1996	Buschmann MD, Hunziker EB, Kim YJ, Grodzinsky AJ. Altered aggrecan synthesis correlates with cell and nucleus structure in statically compressed cartilage. J Cell Sci. February 1996;109(2):499-508.
1986	Schneiderman R, Keret D, Maroudas A. Effects of mechanical and osmotic pressure on the rate of glycosaminoglycan synthesis in the human adult femoral head cartilage: an in vitro study. J Orthop Res. 1986;4(4):393-408.
1988	Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physicochemical determinants of the chondrocyte biosynthetic response. J Orthop Res. November 1988;6(6):777-792.
1989	Sah RL-Y, Kim Y-J, Doong J-YH, Grodzinsky AJ, Plass AHK, Sandy JD. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res. 1989;7(5):619-636.
1991	Hall AC, Urban JPG, Gehl KA. The effects of hydrostatic pressure on matrix synthesis in articular cartilage. J Orthop Res. January 1991;9(1):1-10.
1992	Parkkinen JJ, Lammi MJ, Helminen HJ, Tammi M. Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro. J Orthop Res. 1992;10(5):610-620.
1993	Burton-Wurster N, Vernier-Singer M, Farquhar T, Lust G. Effect of compressive loading and unloading on the synthesis of total protein, proteoglycan, and fibronectin by canine cartilage explants. J Orthop Res. 1993;11(5):717-729.
1994	Freeman PM, Natarajan RN, Kimura JH, Andriacchi TP. Chondrocyte cells respond mechanically to compressive loads. J Orthop Res. May 1994;12(3):311-320.
1995	Ohshima H, Urban JPG, Bergel DH. Effect of static load on matrix synthesis rates in the intervertebral disc measured in vitro by a new perfusion technique. J Orthop Res. January 1995;13(1):22-29.
1996	Smith RL, Rusk SF, Ellison BE, Wessells P, Tsuchiya K, Carter DR, Caler WE, Sandell LJ, Schurman DJ. In vitro stimulation of articular chondrocyte mRNA and extracellular matrix synthesis by hydrostatic pressure. J Orthop Res. 1996;14(1):53-60.
1997	Lee DA, Bader DL. Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose. J Orthop Res. March 1997;15(2):181-188.
1997	Wong M, Wuethrich P, Buschmann MD, Eggli P, Hunziker E. Chondrocyte biosynthesis correlates with local tissue strain in statically compressed adult articular cartilage. J Orthop Res. March 1997;15(2):189-196.
2002	Davisson T, Kunig S, Chen A, Sah R, Ratcliffe A. Static and dynamic compression modulate matrix metabolism in tissue engineered cartilage. J Orthop Res. July 2002;20(4):842-848.
2000	Smith RL, Lin J, Trindade MCD, Shida J, Kajiyama G, Vu T, Hoffman AR, van der Meulen MCH, Goodman SB, Schurman DJ, Carter DR. Time-dependent effects of intermittent hydrostatic pressure on articular chondrocyte type II collagen and aggrecan mRNA expression. J Rehab Res Dev. March–April 2000;37(2):153-181.
1994	Guilak F, Meyer BC, Ratcliffe A, Mow VC. The effects of matrix compression on proteoglycan metabolism in articular cartilage explants. Osteoarthritis Cartilage. June 1994;2(2):91-101.
1988	Urban JPG, McMullin JF. Swelling pressure of the lumbar intervertebral discs influence of age, spinal level, composition, and degeneration. Spine. February 1988;13(2):179-187.
2001	Smith CL. Some Aspects of the Biomechanics of Articular Cartilage Repair [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2001.
2002	Sun D. Theoretical and Experimental Investigations of the Mechano-Electrochemical Properties of Articular Cartilage, a Charged -Hydrated -Soft, Biological Tissue [PhD thesis]. Columbia University; 2002.
2003	Mauck RL. Functional Tissue Engineering of Articular Cartilage: The Effect of Physical Forces on the in Vitro Growth of Engineered Constructs [PhD thesis]. Columbia University; 2003.
2008	Lima EG. The Tissue-Engineering of Functional Osteochondral Constructs for Cartilage Repair [PhD thesis]. Columbia University; 2008.
2010	Degala S. Fluid Flow Regulates Articular Chondrocyte Mechanotransduction Pathways in 3D Culture [PhD thesis]. Ithaca, NY: Cornell University; May 2010.
2001	Erickson GR. Articular Chondrocyte Response to Osmotic Stress: The Involvement of Calcium and the Cytoskeleton in Cellular Volume Adaptation and Regulation [PhD thesis]. Duke University; 2001.
2005	Pritchard SE. Interleukin-1 Initiates Intracellular Calcium Transients in Articular Chondrocytes and Modulates Their Response to Osmotic Stress: The Role of F-Actin and TRPV4 [PhD thesis]. Duke University; 2005.
2008	Estes BT. Functional Tissue Engineering of Cartilage Using Adipose-Derived Stem Cells [PhD thesis]. Duke University; 2008.
2006	Gemmiti CV. Effect of Fluid Flow on Tissue-Engineered Cartilage in a Novel Bioreactor [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; December 2006.
1986	Gray ML. Physical Regulation of Epiphyseal Cartilage Biosynthesis: Responses to Electrical, Mechanical, and Chemical Signals [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; July 1986.
1990	Sah RL-Y. Biophysical Regulation of Matrix Systhesis, Assembly, and Degradation in Dynamically Compressed Calf Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; 1990.
1996	Quinn TM. Articular Cartilage: Matrix Assembly, Mediation of Chondrocyte Metabolism, and Response to Compression [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1996.
2009	Chen S. Regulation of Lubricin Gene Expression and Synthesis in Cartilage by Mechanical Injury [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2009.
2013	Li Y. In Vitro Model of Injury/cytokine-Induced Cartilage Catabolism Modulated by Dynamic Compression, Growth Factors, and Glucocorticoids [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2013.
2015	Zignego DL. In Vitro and in Vivo Systems Mechanobiology of Osteoarthritic Chondrocytes [PhD thesis]. Bozeman, MT: Montana State University; July 2015.
2000	Langelier E. Le rôle du cytosquelette dans la mécanique des cellules du cartilage, les chondrocytes [PhD thesis]. École polytechnique de Montréal; December 2000.
2012	Kaupp JA. Simulated Joint Loading Enhances the Expression of of Superficial Zone Markers in Tissue Engineered Cartilage Constructs [PhD thesis]. Queen's University; February 2012.
2012	Khan AA. Effects of Additional Sodium Bicarbonate on Extra/intra Cellular Factors in a Continuous Flow Bioreactor for the Production of Tissue Engineered Articular Cartilage [PhD thesis]. Queen's University; October 2012.
1990	Wong M. The Role of Mechanical Loading Histories in Skeletal Morphogenesis [PhD thesis]. Stanford University; June 1990.
1997	Stevens SS. Mechanical Regulation of Articular Cartilage Development, Maintenance and Degeneration [PhD thesis]. Stanford University; August 1997.
1997	Wren TAL. Structure-Function Relationships for Soft Skeletal Connective Tissues [PhD thesis]. Stanford University; June 1997.
1997	Chen AC. Electromechanical Properties of Normal Cartilage and Biomechanical Regulation of Transplanted Chondrocytes: Implications for Articular Cartilage Tissue Engineering [PhD thesis]. San Diego (UCSD), University of California; 1997.
2001	Davisson TH. Biophysical Regulation of Metabolic Balance in Tissue Engineered Articular Cartilage [PhD thesis]. San Diego (UCSD), University of California; 2001.
2002	Li KW. Regulation of Chondrocytes by Static and Dynamic Loading in Articular Cartilage Repair [PhD thesis]. San Diego (UCSD), University of California; 2002.
2006	Nugent GE. Biomechanical Regulation of Articular Cartilage Metabolism of Proteoglycan 4 and Articular Surface Integrity [PhD thesis]. San Diego (UCSD), University of California; 2006.
2012	Nguyen QT. Mechanobiology and Biomechanics of Articular Cartilage Repair [PhD thesis]. San Diego (UCSD), University of California; 2012.
2020	Black A. Integrin Alpha 1 Beta 1 Has Limited Influence on Epidermal Growth Factor Receptor Signaling But Sex-Dependent Effects on Estrogen Receptor Beta in Murine Knee Chondrocytes [Master's thesis]. University of Guelph; September 2020.
2010	Wartella KA. Effect of Mechanical Stimulation on Mesenchymal Stem Cell Seeded Cartilage Constructs [PhD thesis]. Richmond, VA: Virginia Commonwealth University; August 2010.

Year	Entry
1978	Venn MF. Variation of chemical composition with age in human femoral head cartilage. Ann Rheum Dis. April 1978;37(2):168-174.
1979	Maroudas A. Physicochemical properties of articular cartilage. In: Freeman MAR, ed. Adult Articular Cartilage. 2nd ed. Kent, England: Pitman Medical; 1979:215-290.