Elasticity of articular cartilage:​ effect of ions and viscous solutions

Sokoloff, Leon<sup>1</sup>

Affiliations

¹Laboratory of Experimental Pathology, National Institute of Arthritis and Metabolic Diseases, Bethesda 14, Maryland

Abstract

The deformability of articular cartilage is increased by cations, more so by polyvalent than monovalent ones. Trivalent cations also depress elastic recovery. Failure of viscous solutions to alter the elastic behavior suggests ultrafiltration by cartilage as a possible mechanism in synovial lubrication.

Links

DOI: 10.1126/science.141.3585.1055

PubMed: 14043349

WoS: A19633051C00218

History

Accepted: 1963-07-12

Cited Works (2)

Year	Entry
1963	Elmore SM, Sokoloff L, Norris G, Carmeci P. Nature of "imperfect" elasticity of articular cartilage. J Appl Physiol. 1963;18(2):393-396.
1962	McCutchen CW. The frictional properties of animal joints. Wear. January–February 1962;5(1):1-17.

Cited By (29)

Year	Entry
1965	Linn FC, Sokoloff L. Movement and composition of interstitial fluid of cartilage. Arthritis Rheum. August 1965;8(4):481-494.
1975	Walker PS, Erkman MJ. The role of the menisci in force transmission across the knee. Clin Orthop Relat Res. June 1975;109:184-192.
1971	Hayes WC, Mockros LF. Viscoelastic properties of human articular cartilage. J Appl Physiol. October 1971;31(4):562-568.
1972	Hayes WC, Keer LM, Herrmann G, Mockros LF. A mathematical analysis for indentation tests of articular cartilage. J Biomech. September 1972;5(5):541-551.
1976	Hori RY, Mockros LF. Indentation tests of human articular cartilage. J Biomech. 1976;9(4):259-268.
1977	Parsons JR, Black J. The viscoelastic shear behavior of normal rabbit articular cartilage. J Biomech. 1977;10(1):21-29.
1978	Hayes WC, Bodine AJ. Flow-independent viscoelastic properties of articular cartilage matrix. J Biomech. 1978;11(8-9):407-419.
1984	Mow VC, Holmes MH, Lai WM. Fluid transport and mechanical properties of articular cartilage: a review. J Biomech. 1984;17(5):377-394.
1987	Mak AF, Lai WM, Mow VC. Biphasic indentation of articular cartilage, I: theoretical analysis. J Biomech. 1987;20(7):703-714.
1992	Chimich D, Shrive N, Frank C, Marchuk L, Bray R. Water content alters viscoelastic behaviour of the normal adolescent rabbit medial collateral ligament. J Biomech. August 1992;25(8):831-837.
1987	Eisenberg SR, Grodzinsky AJ. The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. J Biomech Eng. February 1987;109(1):79-89.
1970	Radin EL, Paul IL, Lowy M. A comparison of the dynamic force transmitting properties of subchondral bone and articular cartilage. J Bone Joint Surg. April 1970;52A(3):444-456.
1981	Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties. J Biomech Eng. November 1981;103(2):280-292.
1985	Eisenberg SR, Grodzinsky AJ. Swelling of articular cartilage and other connective tissues: electromechanochemical forces. J Orthop Res. 1985;3(2):148-159.
2001	Smith CL. Some Aspects of the Biomechanics of Articular Cartilage Repair [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2001.
2017	Wahlquist JA. Zonal Articular Cartilage Possesses Complex Mechanical Behavior Spanning Multiple Length Scales: Dependence on Chemical Heterogeneity, Anisotropy, and Microstructure [PhD thesis]. Boulder, CO: University of Colorado; 2017.
1989	Athanasiou KA. Biomechanical Assessment of Articular Cartilage Healing and Interspecies Variability [PhD thesis]. Columbia University; 1989.
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2002	Sun D. Theoretical and Experimental Investigations of the Mechano-Electrochemical Properties of Articular Cartilage, a Charged -Hydrated -Soft, Biological Tissue [PhD thesis]. Columbia University; 2002.
2007	Lu X. Indentation Analysis of Articular Cartilage Using the Triphasic Mixture Theory [PhD thesis]. Columbia University; 2007.
2009	Canal Guterl C. Contact Mechanics of Articular Layers: 2D Strain Fields and Their Relation to Tissue Inhomogeneity [PhD thesis]. Columbia University; 2009.
1970	Kempson GE. Mechanical Properties of Human Articular Cartilage [PhD thesis]. Imperial College London; March 1970.
2015	Genemaras AA. Early Detection and Intervention Strategies for Acute Cartilage Injury After Intact Joint Impact: In-Vitro Porcine Knee Model [PhD thesis]. University of Miami; August 2015.
1983	Eisenberg SR. Nonequilibrium Electromechanical Interactions in Cartilage: Swelling and Electrokinetics Cambridge, MA: Massachusetts Institute of Technology; February 1983.
1986	Gray ML. Physical Regulation of Epiphyseal Cartilage Biosynthesis: Responses to Electrical, Mechanical, and Chemical Signals [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; July 1986.
2016	Young WT. Cartilage Stress Relaxation Induced by Intra-Tissue Transport of Cationic Nanoparticles: Implications for Post-Traumatic Osteoarthritis Drug Delivery [Master's thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2016.
1985	Kwan MK-W. A Finite Deformation Theory for Nonlinearly Permeable Cartilage and Other Soft Hydrated Connective Tissues and Rheological Study of Cartilage Proteoglycans [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; December 1985.
2008	Moss IL. Modified-Hyaluronan and Elastin-Like Polypeptide Composite Material for Tissue Engineering of the Nucleus Pulposus [Master's thesis]. University of Toronto; 2008.
2009	Forman J. The Structural Characteristics of the Costal Cartilage: The Roles of Calcification and the Perichondrium, and the Representation of the Costal Cartilage in Finite Element Models of the Human Body [PhD thesis]. Charlottesville, VA: University of Virginia; August 2009.