Nutrition of the intervertebral disk:​ an in vivo study of solute transport

Urban, J. P. G.<sup>1</sup>; Holm, S.<sup>2</sup>; Maroudas, A.<sup>1</sup>; Nachemson, A.<sup>2</sup>

Affiliations

¹Biomechanics Unit, Imperial College, and Bone and Joint Research Unit, London Hospital Medical College, London

²Sahlgren Hospital, Goteborg, Sweden

Links

PubMed: 608268

History

Received: 1977-04-27

Cited Works (6)

Year	Entry
1968	Maroudas A. Physicochemical properties of cartilage in the light of ion exchange theory. Biophys J. May 1968;8(5):575-595.
1970	Maroudas A. Distribution and diffusion of solutes in articular cartilage. Biophys J. May 1970;10(5):365-379.
1975	Maroudas A, Stockwell RA, Nachemson A, Urban J. Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro. J Anat. September 1975;120(1):113-130.
1977	Urban JPG. Fluid and Solute Transport in the Inter-Vertebral Disc [PhD thesis]. Imperial College London; June 1977.
1970	Nachemson A, Lewin T, Maroudas A, Freeman MAR. In vitro diffusion of dye through the end-plates and the annulus fibrosus of human lumbar inter-vertebral discs. Acta Orthop Scand. 1970;41(3):589-607.
1975	Maroudas A. Biophysical chemistry of cartilaginous tissues with special reference to solute and fluid transport. Biorheology. 1975;12(3-4):233-248.

Cited By (27)

Year	Entry
2003	Gu WY, Yao H. Effects of hydration and fixed charge density on fluid transport in charged hydrated soft tissues. Ann Biomed Eng. November 2003;31(10):1162-1170.
1981	Holm S, Maroudas A, Urban JPG, Selstam G, Nachemson A. Nutrition of the intervertebral disc: solute transport and metabolism. Connect Tissue Res. 1981;8(2):101-119.
2004	Bibby SRS, Urban JPG. Effect of nutrient deprivation on the viability of intervertebral disc cells. Eur Spine J. December 2004;13(8):695-701.
1987	Torzilli PA, Adams TC, Mis RJ. Transient solute diffusion in articular cartilage. J Biomech. 1987;20(2):203-214.
2004	Ferguson SJ, Ito K, Nolte L-P. Fluid flow and convective transport of solutes within the intervertebral disc. J Biomech. February 2004;37(2):213-221.
1983	Sandover J. Dynamic loading as a possible source of low-back disorders. Spine. September 1983;8(6):652-658.
1989	Roberts S, Menage J, Urban JPG. Biochemical and structural properties of the cartilage end-plate and its relation to the intervertebral disc. Spine. February 1989;14(2):166-174.
1999	Gu WY, Mao XG, Foster RJ, Weidenbaum M, Mow VC, Rawlins BA. The anisotropic hydraulic permeability of human lumbar anulus fibrosus: influence of age, degeneration, direction, and water content. Spine. December 1, 1999;24(23):2449-2455.
2002	Boos N, Weissbach S, Rohrbach H, Weiler C, Spratt KF, Nerlich AG. Classification of age-related changes in lumbar intervertebral discs. Spine. December 1, 2002;27(23):2631-2644.
2004	Urban JPG, Smith S, Fairbank JCT. Nutrition of the intervertebral disc. Spine. December 1, 2004;29(23):2700-2709.
2006	Warden KE. Localized Trabecular Damage Adjacent to Interbody Fusion Devices [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2006.
2015	Wright GJ. Biomechanical Characterization and Modeling of the Human TMJ Disc [PhD thesis]. Clemson, SC: Clemson University; May 2015.
2020	Sloan SR Jr. Tissue-Engineered Annulus Fibrosus Repair and Nucleus Pulposus Augmentation in Pre-Clinical Models of Intervertebral Disc Degeneration [PhD thesis]. Ithaca, NY: Cornell University; May 2020.
2020	Ashinsky BG. Multiscale and Multimodal Structure-Function Analysis of Intervertebral Disc Degeneration and Regeneration [PhD thesis]. Drexel University; May 2020.
2012	Lee EJ. Direct Differentiation of Mouse Induced Pluripotent Stem Cells Into Nucleus Pulposus-Like Cells [Master's thesis]. Duke University; 2012.
1977	Urban JPG. Fluid and Solute Transport in the Inter-Vertebral Disc [PhD thesis]. Imperial College London; June 1977.
2004	Yao H. Physical Signals and Solute Transport in Cartilaginous Tissues [PhD thesis]. University of Miami; August 2004.
2009	Travascio F. Modeling Molecular Transport and Binding Interactions in Intervertebral Disc [PhD thesis]. University of Miami; December 2009.
2011	Yuan T-Y. Innovative Methods to Determine Material Properties of Cartilaginous Tissues and Application for Tissue Engineering [PhD thesis]. University of Miami; August 2011.
2016	Zhu Q. Numerical Modeling of Intervertebral Disc Degeneration and Repair [PhD thesis]. University of Miami; May 2016.
2017	Kleinhans KL. Transport Properties in Porcine Meniscus Fibrocartilage [PhD thesis]. University of Miami; August 2017.
2014	Anderst W. In Vivo Cervical Spine Kinematics, Arthrokinematics and Disc Loading in Asymptomatic Control Subjects and Anterior Fusion Patients [PhD thesis]. University of Pittsburgh; 2014.
2008	Mokhbi-Soukane D. Études numériques de la diffusion couplée d'oxygène, glucose et d'acide lactique dans le disque intervertébral [PhD thesis]. École polytechnique de Montréal; June 2008.
2019	Bezci SE. Time-Dependent Characterization of Fluid Flow Into the Intervertebral Disc [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2019.
2017	Berg-Johansen B. Characterization of the Spinal Disc-Vertebra Interface and Its Relation to Injury and Back Pain [PhD thesis]. San Francisco, University of California; 2017.
2008	Korecki CL. Effects of Compression Loading, Injury, and Age on Intervertebral Disc Mechanics, Biology and Metabolism Using Large Animal Organ and Cell Culture Systems [PhD thesis]. University of Vermont; May 2008.
2016	Balkovec C. Intervertebral Disc Height Loss and Restoration: Outcomes and Implications [PhD thesis]. University of Waterloo; 2016.