Setton, Lori A.

Links

AcademicTree: 717994

Academic genealogy

Doctoral Descendants

Affiliations (3)

Name	Count	Oldest	Newest
Duke University	21	1995	2014
Columbia University	6	1993	1996
Duke University Medical Center	9	1999	2007

Papers (32)

Year	Article	Times Cited	Times Cited (no self-citations)
1994	Mow VC, Bachrach NM, Setton LA, Guilak F. Stress, strain, pressure and flow fields in articular cartilage and chondrocytes. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:345-379.	40	15
2003	Guilak F, Setton LA. Functional tissue engineering and the role of biomechanical signaling in articular cartilage repair. In: Guilak F, Butler DL, Goldstein SA, Mooney DJ, eds. Functional Tissue Engineering. New York, NY: Inc., Springer-Verlag; 2003:277-290.	2	1
2005	Alexopoulos LG, Setton LA, Guilak F. The biomechanical role of the chondrocyte pericellular matrix in articular cartilage. Acta Biomater. May 2005;1(3):317-325.	45	32
2006	Guilak F, Alexopoulos LG, Upton ML, Youn I, Choi JB, Cao L, Setton LA, Haider MA. The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage. Annals NY Acad Sci. April 2006;1068(1):498-512.	39	33
1993	Setton LA, Zhu W, Mow VC. The biphasic poroviscoelastic behavior of articular cartilage: role of the surface zone in governing the compressive behavior. J Biomech. April–May 1993;26(4-5):581-592.	94	73
1997	Iatridis JC, Setton LA, Weidenbaum M, Mow VC. The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear. J Biomech. October 1997;30(10):1005-1013.	32	27
1998	Iatridis JC, Setton LA, Foster RJ, Rawlins BA, Weidenbaum M, Mow VC. Degeneration affects the anisotropic and nonlinear behaviors of human anulus fibrosus in compression. J Biomech. June 1998;31(6):535-544.	72	58
1999	Narmoneva DA, Wang JY, Setton LA. Nonuniform swelling-induced residual strains in articular cartilage. J Biomech. April 1999;32(4):401-408.	32	29
2005	Alexopoulos LG, Williams GM, Upton ML, Setton LA, Guilak F. Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage. J Biomech. March 2005;38(3):509-517.	30	20
2007	Choi JB, Youn I, Cao L, Leddy HA, Gilchrist CL, Setton LA, Guilak F. Zonal changes in the three-dimensional morphology of the chondron under compression: the relationship among cellular, pericellular, and extracellular deformation in articular cartilage. J Biomech. 2007;40(12):2596-2603.	35	30
1998	Setton LA, Tohyama H, Mow VC. Swelling and curling behaviors of articular cartilage. J Biomech Eng. June 1998;120(3):355-361.	36	26
2000	Elliott DM, Setton LA. A linear material model for fiber-induced anisotropy of the anulus fibrosus. J Biomech Eng. April 2000;122(2):173-179.	24	12
2001	Elliott DM, Setton LA. Anisotropic and inhomogeneous tensile behavior of the human anulus fibrosus: experimental measurement and material model predictions. J Biomech Eng. June 2001;123(3):256-263.	54	40
2002	Elliott DM, Narmoneva DA, Setton LA. Direct measurement of the Poisson’s ratio of human patella cartilage in tension. J Biomech Eng. April 2002;124(2):223-228.	23	21
2002	LeRoux MA, Setton LA. Experimental and biphasic FEM determinations of the material properties and hydraulic permeability of the meniscus in tension. J Biomech Eng. June 2002;124(3):315-321.	23	22
2003	Baer AE, Laursen TA, Guilak F, Setton LA. The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model. J Biomech Eng. February 2003;125(1):1-11.	23	14
1999	LeRoux MA, Guilak F, Setton LA. Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration. J Biomed Mater Res. October 1999;47(1):46-53.	20	9
1993	Setton LA, Zhu W, Weidenbaum M, Ratcliffe A, Mow VC. Compressive properties of the cartilaginous end-plate of the baboon lumbar spine. J Orthop Res. March 1993;11(2):228-239.	28	23
1994	Setton LA, Mow VC, Müller FJ, Pita JC, Howell DS. Mechanical properties of canine articular cartilage are significantly altered following transection of the anterior cruciate ligament. J Orthop Res. July 1994;12(4):451-463.	74	56
1995	Setton LA, Mow VC, Howell DS. Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament. J Orthop Res. July 1995;13(4):473-482.	42	26
1997	Iatridis JC, Setton LA, Weidenbaum M, Mow VC. Alterations in the mechanical behavior of the human lumbar nucleus pulposus with degeneration and aging. J Orthop Res. March 1997;15(2):318-322.	49	36
1999	Elliott DM, Guilak F, Vail TP, Wang JY, Setton LA. Tensile properties of articular cartilage are altered by meniscectomy in a canine model of osteoarthritis. J Orthop Res. July 1999;17(4):503-508.	34	18
2000	LeRoux MA, Arokoski J, Vail TP, Guilak F, Hyttinen MM, Kiviranta I, Setton LA. Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy. J Orthop Res. May 2000;18(3):383-392.	37	27
2003	Upton ML, Chen J, Guilak F, Setton LA. Differential effects of static and dynamic compression on meniscal cell gene expression. J Orthop Res. November 2003;21(6):963-969.	25	24
2014	Evans CH, Kraus VB, Setton LA. Progress in intra-articular therapy. Nat Rev Rheumatol. January 2014;10(1):11-22.	16	12
1999	Setton LA, Elliott D., Mow VC. Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degeneration. Osteoarthritis Cartilage. January 1999;7(1):2-14.	57	48
2006	Youn I, Choi JB, Cao L, Setton LA, Guilak F. Zonal variations in the three-dimensional morphology of the chondron measured in situ using confocal microscopy. Osteoarthritis Cartilage. September 2006;14(9):889-897.	25	19
1994	Best BA, Guilak F, Setton LA, Zhu W, Saed-Nejad F, Ratcliffe A, Weidenbaum M, Mow VC. Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition. Spine. January 15, 1994;19(2):212-221.	58	43
1995	Acaroglu ER, Iatridis JC, Setton LA, Foster RJ, Mow VC, Weidenbaum M. Degeneration and aging affect the tensile behavior of human lumbar anulus fibrosus. Spine. December 15, 1995;20(24):2690-2701.	57	43
1996	Ebara S, Iatridis JC, Setton LA, Foster RJ, Mow VC, Weidenbaum M. Tensile properties of nondegenerate human lumbar anulus fibrosus. Spine. March 15, 1996;21(4):452-461.	62	54
1996	Iatridis JC, Weidenbaum M, Setton LA, Mow VC. Is the nucleus pulposus a solid or a fluid? mechanical behaviors of the nucleus pulposus of the human intervertebral disc. Spine. May 15, 1996;21(15):1174-1184.	49	39
1999	Guilak F, Ting-Beall HP, Baer AE, Trickey WR, Erickson GR, Setton LA. Viscoelastic properties of intervertebral disc cells: identification of two biomechanically distinct cell populations. Spine. December 1, 1999;24(23):2475-2483.	28	15

Theses (1)

Year	Article	Times Cited	Times Cited (no self-citations)
1993	Setton LA. Effects of Intrinsic Viscoelasticity and Ion-Induced Swelling on the Mechanical Behavior of Articular Cartilage: Theory and Experiments [PhD thesis]. Columbia University; 1993.	0	0

Student Theses (27)

Year	Article	Times Cited
2021	Speer JE. Engineering Nucleus Pulposus Cell-Matrix Interactions With Laminin Ligands for Tissue Regeneration [PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2021.	0
2021	Guang Y. Understanding a Role for Synovium in Intra-Articular Drug Clearance: A Computational and Experimental Approach [PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2021.	0
2021	Berke IM. Evaluating the Structural and Functional Consequences of Traumatic Joint Injury and Their Relation to NF-ΚB in a Non-Invasive Model of Post-Traumatic Osteoarthritis [PhD thesis]. St. Louis, MO: Washington University in St. Louis; January 2021.	0
2021	Barcellona MN. Laminin-Mimetic Peptide-Functionalized Hydrogel Systems for the Phenotypic Modulation of Cells of the Nucleus Pulposus [PhD thesis]. St. Louis, MO: Washington University in St. Louis; January 2021.	0
2020	Berke IM. Evaluating the Structural and Functional Consequences of Traumatic Joint Injury and Their Relation to NF-ΚB in a Non-Invasive Model of Post-Traumatic Osteoarthritis [PhD thesis]. St. Louis, MO: Washington University in St. Louis; 2020.	0
2018	Lam S. Controlling the Oxygen Microenvironment: The Role of HIF-1α in Early Tumor Progression [PhD thesis]. St. Louis, MO: Washington University in St. Louis; August 2018.	0
2017	Leimer EM. Molecular and Functional Changes of Dorsal Root Ganglion Neurons in a Rodent Model of Intervertebral Disc Degeneration [PhD thesis]. Duke University; 2017.	0
2015	Mwangi TK. The Intra-Articular Clearance of Silk Microparticles and Macromolecules in Healthy and Arthritic Rat Knee Joints [PhD thesis]. Duke University; 2015.	0
2015	Hwang PY. Cadherin-Mediated Cell-Cell Interactions Regulates Phenotype and Morphology of Nucleus Pulposus Cells of the Intervertebral Disc [PhD thesis]. Duke University; 2015.	1
2015	Bridgen DT. Regulation of Human Nucleus Pulposus Cell Phenotype and Behavior by Laminin-Mimetic Peptide Substrates [PhD thesis]. Duke University; 2015.	0
2013	Sinclair SM. Development of Depot Forming Elastin-Like Polypeptide-Curcumin Drug Conjugates for Sustained Drug Delivery to Treat Neuroinflammatory Pathologies [PhD thesis]. Duke University; 2013.	0
2013	Francisco AT. Laminin-Functionalized Polyethylene Glycol Hydrogels for Nucleus Pulposus Regeneration [PhD thesis]. Duke University; 2013.	0
2012	Lee EJ. Direct Differentiation of Mouse Induced Pluripotent Stem Cells Into Nucleus Pulposus-Like Cells [Master's thesis]. Duke University; 2012.	0
2012	Hwang PY. Response of Midbrain Pain Receptors in a Rodent Model of Radiculopathy [Master's thesis]. Duke University; 2012.	0
2010	Sinclair SM. Attenuation of Inflammatory Events in Human Intervertebral Disc Cells With a Tumor Necrosis Factor Antagonist [Master's thesis]. Duke University; 2010.	0
2010	Phu D. The Effect of Entrapped Laminin-111 in Three-Dimensional Polyethylene Glycol Gels on the Behavior of Nucleus Pulposus Cells from the Intervertebral Disc [Master's thesis]. Duke University; 2010.	0
2009	Gilchrist CL. The Effects of Extracellular Matrix Mechanics and Composition on the Behaviors of Nucleus Pulposus Cells from the Intervertebral Disc [PhD thesis]. Duke University; 2009.	1
2008	Shamji MF. Evaluation of Elastin-Like Polypeptide to Sustain Perineural Drug Delivery and Development of a Depot-Forming Tumor Necrosis Factor Antagonist for the Treatment of Lumbar Radiculopathy [PhD thesis]. Duke University; 2008.	0
2008	Cao L. Micromechanics of the Pericellular Matrix and Cells in the Intervertebral Disc: Three-Dimensional Finite Element Modeling Based on in Situ Morphology [PhD thesis]. Duke University; 2008.	0
2007	Upton ML. Theoretical Predictions and Experimental Measurements of the Micromechanical Environment of Meniscus Cells [PhD thesis]. Duke University; 2007.	0
2007	Nettles DL. Artificial Neural Network Modeling of Crosslinked Elastin -Like Polypeptide Formulations Parameters Effects on Physical Properties and Cellular Interactions for Cartilage Tissue Engineering [PhD thesis]. Duke University; 2007.	0
2007	Boyd LM. Effects of a Genetic Mutation in Type IX Collagen on Morphology and Metabolism in a Murine Model of Intervertebral Disc Degeneration [PhD thesis]. Duke University; 2007.	0
2005	Betre H. Controlled Intra-Articular Drug Delivery System Based on Thermally Responsive Biopolymers [PhD thesis]. Duke University; 2005.	0
2001	Baer AE. The Micromechanical Environment of Intervertebral Disc Cells [PhD thesis]. Duke University; 2001.	0
2000	Narmoneva DA. Material Property Determination for Normal and Osteoarthritic Articular Cartilage Using a Triphasic Mechano -Chemical Theoretical Model of Osmotic Loading [PhD thesis]. Duke University; 2000.	0
2000	LeRoux MA. Altered Mechanics of the Meniscus With a Healing Tear: Experimental Testing and Biphasic Finite Element Analysis [PhD thesis]. Duke University; 2000.	1
1999	Elliott DM. The Fiber-Induced Anisotropic Material Behaviors of the Anulus Fibrosus of the Intervertebral Disc in Tension [PhD thesis]. Duke University; 1999.	2

Collaborators (18)

Name	Count	Oldest	Newest
Alexopoulos, Leonidas G.	3	2005	2006
Mow, Van C.	14	1993	1999
Erickson, Geoffrey Richard	1	1999	1999
Kraus, Virginia Byers	1	2014	2014
Howell, David S.	2	1994	1995
Guilak, Farshid	13	1994	2007
LeRoux, Michelle Anne	3	1999	2002
Foster, Robert J.	3	1995	1998
Kiviranta, Ilkka	1	2000	2000
Weidenbaum, Mark	8	1993	1998
Vail, Thomas Parker	2	1999	2000
Zhu, Wenbo	3	1993	1994
Narmoneva, Daria A.	2	1999	2002
Elliott, Dawn M.	4	1999	2002
Leddy, Holly Anne	1	2007	2007
Iatridis, James C.	6	1995	1998
Bachrach, Nathaniel M.	1	1994	1994
Ratcliffe, Anthony	2	1993	1994