Predicting fractures in women by using forearm bone densitometry

Gärdsell, Per; Johnell, Olof; Nilsson, Bo E.

Affiliations

¹Department of Orthopaedics, Malmö General Hospital, Lund University, Malmö, Sweden

Abstract and keywords

In 1,076 women the forearm bone mineral content (BMC) had been measured with single photon gamma absorptiometry (SPA) 10–16 years ago. The incidence of fractures incurred in the ensuing years (1975–1985) was recorded. The BMC had been significantly less in those women who were to have the types of fractures that are related to bone fragility but only in women measured during the first post-menopausal decades. From age 50–69, diminished BMC at the distal forearm site was associated with a threefold increase of relative risk whereas at the proximal site there was about a sixfold increase in relative risk. This association was not evident in the pppulation over 70 years of age because of a high frequency of fractures (mostly of the spine) in subjects with relatively high BMC values. Body weight and grip strength were significantly lower in the fracture group over 70 years of age

Keywords: Bone mineral; Fractures; Body weight; Strength; Menopause

Links

DOI: 10.1007/BF0255375

PubMed: 2501005

WoS: A1989U078500001

History

Received: 1987-12-23

Revised: 1988-06-14

Cited Works (1)

Year	Entry
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Cited By (19)

Year	Entry
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1991	Seeley DG, Browner WS, Nevitt MC, Genant HK, Scott JC, Cummings SR; Study of Osteoporotic Fractures Research Group. Which fractures are associated with low appendicular bone mass in elderly women? Ann Intern Med. December 1, 1991;115(11):837-842.
1990	Ross PD, Davis JW, Vogel JM, Wasnich RD. A critical review of bone mass and the risk of fractures in osteoporosis. Calcif Tiss Int. March 1990;46(3):149-161.
1990	Mazess RB. Fracture risk: a role for compact bone. Calcif Tiss Int. October 1990;47(4):191-193.
1991	Gärdsell P, Johnell O, Nilsson BE. The predictive value of bone loss for fragility fractures in women: a longitudinal study over 15 years. Calcif Tiss Int. August 1991;49(2):90-94.
1993	Heaney RP. Is there a role for bone quality in fragility fractures? Calcif Tiss Int. February 1993;53(suppl 1):S3-S6.
1993	Ott SM. When bone mass fails to predict bone failure. Calcif Tiss Int. February 1993;53(suppl 1):S7-S13.
1993	Myers ER, Hecker AT, Rooks DS, Hipp JA, Hayes WC. Geometric variables from DXA of the radius predict forearm fracture load in vitro. Calcif Tiss Int. March 1993;52(3):199-204.
1998	Akhter MP, Cullen DM, Pedersen EA, Kimmel DB, Recker RR. Bone response to in vivo mechanical loading in two breeds of mice. Calcif Tiss Int. November 1998;63(5):442-449.
1990	Cummings SR, Black DM, Nevitt MC, Browner WS, Cauley JA, Genant HK, Mascioli SR, Scott JC, Seeley DG, Steiger P, Vogt TM; The Study of Osteoporotic Fractures Research Group. Appendicular bone density and age predict hip fracture in women. JAMA. February 2, 1990;263(5):665-668.
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