Standardized nomenclature, symbols, and units for bone histomorphometry:​ a 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

Dempster, David W.; Compston, Juliet E.; Drezner, Marc K.; Glorieux, Francis H.; Kanis, John A.; Malluche, Hartmut; Meunier, Pierre J.; Ott, Susan M.; Recker, Robert R.; Parfitt, A. Michael

Year	Entry
2019	Zenzes M, Bortel EL, Fratzl P, Mundlos S, Schuetz M, Schmidt H, Duda GN, Witte F, Zaslansky P. Normal trabecular vertebral bone is formed via rapid transformation of mineralized spicules: a high-resolution 3D ex-vivo murine study. Acta Biomater. March 1, 2019;86:429-440.
2014	Andersen TL, Hauge EM, Rolighed L, Bollerslev J, Kjærsgaard-Andersen P, Delaisse J-M. Correlation between absence of bone remodeling compartment canopies, reversal phase arrest, and deficient bone formation in post-menopausal osteoporosis. Am J Pathol. April 2014;184(4):1142-1151.
2015	Jensen PR, Andersen TL, Hauge E-M, Bollerslev J, Delaissé J-M. A joined role of canopy and reversal cells in bone remodeling: lessons from glucocorticoid-induced osteoporosis. Bone. April 2015;73:16-23.
2016	Meyer LA, Johnson MG, Cullen DM, Vivanco JF, Blank RD, Ploeg H-L, Smith EL. Combined exposure to big endothelin-1 and mechanical loading in bovine sternal cores promotes osteogenesis. Bone. April 2016;85:115-122.
2018	Andreasen CM, Delaisse J-M, van der Eerden BCJ, van Leeuwen JPTM, Ding M, Andersen TL. Understanding age-induced cortical porosity in women: is a negative BMU balance in quiescent osteons a major contributor? Bone. December 2018;117:70-82.
2020	Mulati M, Kobayashi Y, Takahashi A, Numata H, Saito M, Hiraoka Y, Ochi H, Sato S, Ezura Y, Yuasa M, Hirai T, Yoshii T, Okawa A, Inose H. The long noncoding RNA Crnde regulates osteoblast proliferation through the Wnt/β-catenin signaling pathway in mice. Bone. January 2020;130:115076.
2020	Yorgan TA, Sari H, Rolvien T, Windhorst S, Failla AV, Kornak U, Oheim R, Amling M, Schinke T. Mice lacking plastin-3 display a specific defect of cortical bone acquisition. Bone. January 2020;130:115062.
2020	Surowiec RK, Battle LF, Ward FS, Schlecht SH, Khoury BM, Robbins C, Wojtys EM, Caird MS, Kozlof KM. A xenograft model to evaluate the bone forming effects of sclerostin antibody in human bone derived from pediatric osteogenesis imperfecta patients. Bone. January 2020;130:115118.
2020	Rossi M, Buonuomo PS, Battafarano G, Conforti A, Mariani E, Algeri M, Pelle S, D’Agostini M, Macchiaiolo M, De Vito R, Gonfiantini MV, Jenkner A, Rana I, Bartuli A, Del Fattore A. Dissecting the mechanisms of bone loss in Gorham-Stout disease. Bone. January 2020;130:115068.
2020	Sørensen TG, Brent MB, Thomsen JS, Brüel A. Disuse-induced loss of bone mineral density and bone strength is attenuated by post-lactational bone gain in NMRI mice. Bone. January 2020;130:115183.
2020	Li H, Jing Y, Zhang R, Zhang Q, Wang J, Martine A, Feng JQ. Hypophosphatemic rickets accelerate chondrogenesis and cell trans-differentiation from TMJ chondrocytes into bone cells via a sharp increase in β-catenin. Bone. February 2020;131.
2020	Xiao H, Xie X, Wen Y, Tan Y, Shangguan Y, Li B, Magdalou J, Wang H, Chen L. Subchondral bone dysplasia partly participates in prenatal dexamethasone induced-osteoarthritis susceptibility in female offspring rats. Bone. April 2020;133:115245.
2020	Aaltonen L, Koivuviita N, Seppänen M, Tong X, Kröger H, Löyttyniemi E, Metsärinne K. Correlation between ¹⁸F-Sodium Fluoride positron emission tomography and bone histomorphometry in dialysis patients. Bone. May 2020;134:115267.
2020	Pal S, Rashid M, Singh SK, Porwal K, Singh P, Mohamed R, Gayen JR, Wahajuddin M, Chattopadhyay N. Skeletal restoration by phosphodiesterase 5 inhibitors in osteopenic mice: evidence of osteoanabolic and osteoangiogenic effects of the drugs. Bone. June 2020;135:115305.
2020	Robinson JW, Blixt NC, Norton A, Mansky KC, Ye Z, Aparicio C, Wagner BM, Benton AM, Warren GL, Khosla S, Gaddy D, Suva LJ, Potter LR. Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength. Bone. June 2020;135:115320.
2020	Jandl NM, von Kroge S, Stürznickel J, Baranowsky A, Stockhausen KE, Mushumba H, Beil FT, Püschel K, Amling M, Rolvien T. Large osteocyte lacunae in iliac crest infantile bone are not associated with impaired mineral distribution or signs of osteocytic osteolysis. Bone. June 2020;135:115324.
2020	Kosugi K, Tajima T, Menuki K, Okuma KF, Tokuda K, Fukuda H, Okada Y, Tsukamoto M, Yamanaka Y, Zenke Y, Sakai A. Disruption of the aldehyde dehydrogenase 2 gene increases the bone anabolic response to intermittent PTH treatment in an ovariectomized mouse model. Bone. July 2020;136:115370.
2020	Opdebeeck B, Neven E, Millán JL, Pinkerton AB, D'Haese PC, Verhulst A. Pharmacological TNAP inhibition efficiently inhibits arterial media calcification in a warfarin rat model but deserves careful consideration of potential physiological bone formation/mineralization impairment. Bone. August 2020;137:115392.
2020	Ledesma-Colunga MG, Baschant U, Fiedler IAK, Busse B, Hofbauer LC, Muckenthaler MU, Altamura S, Rauner M. Disruption of the hepcidin/ferroportin regulatory circuitry causes low axial bone mass in mice. Bone. August 2020;137:115400.
2020	Simmons JH, Rush ET, Petryk A, Zhou S, Martos-Moreno GÁ. Dual X-ray absorptiometry has limited utility in detecting bone pathology in children with hypophosphatasia: a pooled post hoc analysis of asfotase alfa clinical trial data. Bone. August 2020;137:115413.
2020	Novel-Catin E, Pelletier S, Fouque D, Roux J-P, Chapurlat R, D'Haese P, Behets G, Evenepoel P, Nickolas TL, Lafage-Proust M-H. Quantitative histomorphometric analysis of halved iliac crest bone biopsies yield comparable ROD diagnosis as full 7.5mm wide samples. Bone. September 2020;138:115460.
2020	Hirose K, Ishimoto T, Usami Y, Sato S, Oya K, Nakano T, Komori T, Toyosawa S. Overexpression of Fam20C in osteoblast in vivo leads to increased cortical bone formation and osteoclastic bone resorption [published correction appears in Bone. February 2021;143:115635]. Bone. September 2020;138:115414.
2020	Etani Y, Ebina K, Hirao M, Kitaguchi K, Kashii M, Ishimoto T, Nakano T, Okamura G, Miyama A, Takami K, Goshima A, Kanamoto T, Nakata K, Yoshikawa H. Combined effect of teriparatide and an anti-RANKL monoclonal antibody on bone defect regeneration in mice with glucocorticoid-induced osteoporosis. Bone. October 2020;139:115525.
2020	Wölfel EM, Jähn-Rickert K, Schmidt FN, Wulff B, Mushumba H, Sroga GE, Püschel K, Milovanovic P, Amling M, Campbell GM, Vashishth D, Busse B. Individuals with type 2 diabetes mellitus show dimorphic and heterogeneous patterns of loss in femoral bone quality. Bone. November 2020;140:115556.
2020	Delaisse J-M, Andersen TL, Kristensen HB, Jensen PR, Andreasen CM, Søe K. Re-thinking the bone remodeling cycle mechanism and the origin of bone loss. Bone. December 2020;141:115628.
2021	Dasgupta K, Lessard S, Hann S, Fowler ME, Robling AG, Warman ML. Sensitive detection of Cre-mediated recombination using droplet digital PCR reveals Tg(BGLAP-Cre) and Tg(DMP1-Cre) are active in multiple non-skeletal tissues. Bone. January 2021;142:115674.
2021	Brent MB, Lodberg A, Bromer FD, van der Eerden BCJ, Eijken M, Brüel A, Thomsen JS. Activin type IIA decoy receptor and intermittent parathyroid hormone in combination overturns the bone loss in disuse-osteopenic mice. Bone. January 2021;142:115692.
2021	Makino A, Hasegawa T, Takagi H, Takahashi Y, Hase N, Amizuka N. Frequent administration of abaloparatide shows greater gains in bone anabolic window and bone mineral density in mice: a comparison with teriparatide. Bone. January 2021;142:115651.
2021	Lim K-E, Bullock WA, Horan DJ, Williams BO, Warman ML, Robling AG. Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration. Bone. February 2021;143:115708.
2021	Köhli P, Appelt J, Otto E, Jahn D, Baranowsky A, Bahn A, Erdmann C, Müchler J, Mülleder M, Tsitsilonis S, Keller J. Effects of CGRP receptor antagonism on glucose and bone metabolism in mice with diet-induced obesity. Bone. February 2021;143:115646.
2021	Klose-Jensen R, Hartlev LB, Thomsen JS, Nyengaard JR, Boel LWT, Laursen M, Laurberg TB, Stengaard-Pedersen K, Hauge E-M. Calcified cartilage in patients with osteoarthritis of the hip compared to that of healthy subjects: a design-based histological study. Bone. February 2021;143:115660.
2021	Coates BA, McKenzie JA, Yoneda S, Silva MJ. Interleukin-6 (IL-6) deficiency enhances intramembranous osteogenesis following stress fracture in mice. Bone. February 2021;143:115737.
2021	Androjna C, Yee CS, White CR, Waldorff EI, Ryaby JT, Zborowski M, Alliston T, Midura RJ. A comparison of alendronate to varying magnitude PEMF in mitigating bone loss and altering bone remodeling in skeletally mature osteoporotic rats. Bone. February 2021;143:115761.
2021	Siddiqui JA, Le Henaff C, Johnson J, He Z, Rifkin DB, Partridge NC. Osteoblastic monocyte chemoattractant protein-1 (MCP-1) mediation of parathyroid hormone's anabolic actions in bone implicates TGF-β signaling. Bone. February 2021;143:115762.
2021	Hrdlicka HC, Pereira RC, Shin B, Yee S-P, Deymier AC, Lee S-K, Delany AM. Inhibition of miR-29-3p isoforms via tough decoy suppresses osteoblast function in homeostasis but promotes intermittent parathyroid hormone-induced bone anabolism. Bone. February 2021;143:115779.
2021	Hughes-Austin JM, Dwight KD, Ginsberg C, Tipps A, Salusky IB, Pereira RC, Ix JH. Regional variation in bone turnover at the iliac crest versus the greater trochanter. Bone. February 2021;143:115604.
2021	Teguh DA, Nustad JL, Craven AE, Brooks DJ, Arlt H, Hu D, Baron R, Lanske B, Bouxsein ML. Abaloparatide treatment increases bone formation, bone density and bone strength without increasing bone resorption in a rat model of hindlimb unloading. Bone. March 2021;144:115801.
2021	Lee S, Liu P, Ahmad M, Tuckermann JP. Leukemia inhibitory factor treatment attenuates the detrimental effects of glucocorticoids on bone in mice. Bone. April 2021;145:115843.
2021	Boraschi-Diaz I, Chen G, Polak-Nachumow J, Young RN, Rauch F. Effects of treatment with a bone-targeted prostaglandin E2 receptor 4 agonist C3 (Mes-1007) in a mouse model of severe osteogenesis imperfecta. Bone. April 2021;145:115867.
2020	Kushioka J, Kaito T, Okada R, Ishiguro H, Bal Z, Kodama J, Chijimatsu R, Pye M, Narimatsu M, Wrana JL, Inoue Y, Ninomiya H, Yamamoto S, Saitou T, Yoshikawa H, Imamura T. A novel negative regulatory mechanism of Smurf2 in BMP/sSmad signaling in bone. Bone Res. 2020;8:41.
2020	Albiol L, Büttner A, Pflanz D, Mikolajewicz N, Birkhold AI, Kramer I, Kneissel M, Duda GN, Checa S, Willie BM. Effects of long-term sclerostin deficiency on trabecular bone mass and adaption to limb loading differ in male and female mice. Calcif Tiss Int. April 2020;106(4):415-430.
2020	Cardinal M, Dessain A, Roels T, Lafont S, Ominsky MS, Devogelaer J-P, Chappard D, Mabilleau G, Ammann P, Nyssen-Behets C, Manicourt DH. Sclerostin-antibody treatment decreases fracture rates in axial skeleton and improves the skeletal phenotype in growing oim/oim mice. Calcif Tiss Int. May 2020;106(5):494-508.
2020	Williams EAJ, Douard V, Sugimoto K, Inui H, Devime F, Zhang X, Kishida K, Ferraris RP, Fritton JC. Bone growth is influenced by fructose in adolescent male mice lacking ketohexokinase (KHK). Calcif Tiss Int. May 2020;106(5):541-552.
2020	Al Saedi A, Chen L, Phu S, Vogrin S, Miao D, Ferland G, Gaudreau P, Duque G. Age-related increases in marrow fat volumes have regional impacts on bone cell numbers and structure. Calcif Tiss Int. August 2020;107(2):126-134.
2020	Maurotti S, Russo C, Musolino V, Nucera S, Gliozzi M, Scicchitano M, Bosco F, Morittu VM, Ragusa M, Mazza E, Pujia R, Gazzaruso C, Britti D, Valenti MT, Deiana M, Romeo S, Giannini S, Carbonare LD, Mollace V, Pujia A, Montalcini T. Effects of C-peptide replacement therapy on bone microarchitecture parameters in streptozotocin-diabetic rats. Calcif Tiss Int. September 2020;107(3):266-280.
2020	Mieczkowska A, Millar P, Chappard D, Gault VA, Mabilleau G. Dapagliflozin and liraglutide therapies rapidly enhanced bone material properties and matrix biomechanics at bone formation site in a type 2 diabetic mouse model. Calcif Tiss Int. September 2020;107(3):281-293.
2020	Fujita R, Ota M, Sato D, Nakazawa D, Kimura-Suda H, Nakamura F, Shimizu T, Kobayashi H, Iwasaki N, Takahata M. Comparison of the efficacy and renal safety of bisphosphonate between low-dose/high-frequency and high-dose/low-frequency regimens in a late-stage chronic kidney disease rat model. Calcif Tiss Int. October 2020;107(4):389-402.
2020	Qiu S, Divine G, Warner E, Rao SD. Reference intervals for bone histomorphometric measurements based on data from healthy premenopausal women. Calcif Tiss Int. December 2020;107(6):543-550.
2020	Corsi A, Palmisano B, Spica E, Di Filippo A, Coletta I, Venti MDS, Labella R, Fabretti F, Donsante S, Remoli C, Serafini M, Riminucci M. Zoledronic acid in a mouse model of human fibrous dysplasia: ineffectiveness on tissue pathology, formation of "giant osteoclasts" and pathogenetic implications. Calcif Tiss Int. December 2020;107(6):603-610.
2021	Rolvien T, Jandl NM, Stürznickel J, Beil FT, Kötter I, Oheim R, Lohse AW, Barvencik F, Amling M. Clinical and radiological characterization of patients with immobilizing and progressive stress fractures in methotrexate osteopathy. Calcif Tiss Int. February 2021;108(2):219-230.
2021	Waltenberger L, Beitel S, Benecker B, Heimel P, Weninger W, Kanz F. A histological comparison of non-human rib models suited for sharp force trauma analysis. Forensic Sci Int. February 2021;319:110661.
2015	Maquer G, Musy SN, Wandel J, Gross T, Zysset PK. Bone volume fraction and fabric anisotropy are better determinants of trabecular bone stiffness than other morphological variables. J Bone Miner Res. June 2015;30(6):1000-1008.
2017	Lassen NE, Andersen TL, Pløen GG, Søe K, Hauge EM, Harving S, Eschen GET, Delaisse J-M. Coupling of bone resorption and formation in real time: new knowledge gained from human Haversian BMUs. J Bone Miner Res. July 2017;32(7):1395-1405.
2019	Li Y, Shi Z, Jules J, Chen S, Kesterson RA, Zhao D, Zhang P, Feng X. Specific RANK cytoplasmic motifs drive osteoclastogenesis. J Bone Miner Res. October 2019;34(10):1938-1951.
2019	Bullock WA, Hoggatt AM, Horan DJ, Lewis KJ, Yokota H, Hann S, Warman ML, Sebastian A, Loots GG, Pavalko FM, Robling AG. Expression of a degradation‐resistant β‐catenin mutant in osteocytes protects the skeleton from mechanodeprivation‐induced bone wasting. J Bone Miner Res. October 2019;34(10):1964-1975.
2020	Cheng Z, Li A, Tu C, Santa Maria C, Szeto N, Herberger A, Chen T, Song F, Wang J, Liu X, Shoback DM, Chang W. Calcium‐sensing receptors in chondrocytes and osteoblasts are required for callus maturation and fracture healing in mice. J Bone Miner Res. January 2020;35(1):143-154.
2020	Noda H, Guo J, Khatri A, Dean T, Reyes M, Armanini M, Brooks DJ, Martins JS, Schipani E, Bouxsein ML, Demay MB, Potts JT Jr, Jüppner H, Gardella TJ. An inverse agonist ligand of the PTH receptor partially rescues skeletal defects in a mouse model of Jansen's metaphyseal chondrodysplasia. J Bone Miner Res. March 2020;35(3):540-549.
2020	Chen NX, Srinivasan S, O'Neill K, Nickolas TL, Wallace JM, Allen MR, Metzger CE, Creecy A, Avin KG, Moe SM. Effect of advanced glycation end‐products (AGE) lowering drug ALT‐711 on biochemical, vascular, and bone parameters in a rat model of CKD‐MBD. J Bone Miner Res. March 2020;35(3):608-617.
2020	Henaff CL, Ricarte F, Finnie B, He Z, Johnson J, Warshaw J, Kolupaeva V, Partridge NC. Abaloparatide at the same dose has the same effects on bone as PTH (1‐34) in mice. J Bone Miner Res. April 2020;35(4):714-724.
2020	Li H, Sun H, Qian B, Feng W, Carney D, Miller J, Hogan MV, Wang L. Increased expression of FGF‐21 negatively affects bone homeostasis in dystrophin/utrophin double knockout mice. J Bone Miner Res. April 2020;35(4):738-752.
2020	Wang C, Xiao J, Nowak K, Gunasekera K, Alippe Y, Speckman S, Yang T, Kress D, Abu‐Amer Y, Hottiger MO, Mbalaviele G. PARP1 hinders histone H2B occupancy at the NFATc1 promoter to restrain osteoclast differentiation. J Bone Miner Res. April 2020;35(4):776-788.
2020	Shin B, Kupferman J, Schmidt E, Polleux F, Delany AM, Lee S. Rac1 inhibition via Srgap2 restrains inflammatory osteoclastogenesis and limits the clastokine, SLIT3. J Bone Miner Res. April 2020;35(4):789-800.
2020	Zhou Y, Yang Y, Jing Y, Yuan T, Sun L, Tao B, Liu J, Zhao H. BMP9 reduces bone loss in ovariectomized mice by dual regulation of bone remodeling. J Bone Miner Res. May 2020;35(5):978-993.
2020	Chandra A, Lagnado AB, Farr JN, Monroe DG, Park S, Hachfeld C, Tchkonia T, Kirkland JL, Khosla S, Passos JF, Pignolo RJ. Targeted reduction of senescent cell burden alleviates focal radiotherapy‐related bone loss. J Bone Miner Res. June 2020;35(6):1119-1131.
2020	Dempster DW, Chines A, Bostrom MP, Nieves JW, Zhou H, Chen L, Pannacciulli N, Wagman RB, Cosman F. Modeling‐based bone formation in the human femoral neck in subjects treated with denosumab. J Bone Miner Res. July 2020;35(7):1282-1288.
2020	Recker R, Dempster D, Langdahl B, Giezek H, Clark S, Ellis G, de Villiers T, Valter I, Zerbini CAF, Cohn D, Santora A, Duong LT. Effects of odanacatib on bone structure and quality in postmenopausal women with osteoporosis: 5‐year data from the Phase 3 Long‐term Odanacatib Fracture Trial (LOFT) and its extension. J Bone Miner Res. July 2020;35(7):1289-1299.
2020	Howaldt A, Hennig AF, Rolvien T, Rössler U, Stelzer N, Knaus A, Böttger S, Zustin J, Geißler S, Oheim R, Amling M, Howaldt H, Kornak U. Adult osteosclerotic metaphyseal dysplasia with progressive osteonecrosis of the jaws and abnormal bone resorption pattern due to a LRRK1 splice site mutation. J Bone Miner Res. July 2020;35(7):1322-1332.
2020	Rolvien T, Milovanovic P, Schmidt FN, von Kroge S, Wölfel EM, Krause M, Wulff B, Püschel K, Ritchie RO, Amling M, Busse B. Long‐term immobilization in elderly females causes a specific pattern of cortical bone and osteocyte deterioration different from postmenopausal osteoporosis. J Bone Miner Res. July 2020;35(7):1343-1351.
2020	Gobron B, Bouvard B, Vyavahare S, Blom LV, Pedersen KK, Windeløv JA, Boer GA, Harada N, Zhang S, Shimazu‐Kuwahara S, Wice B, Inagaki N, Legrand E, Flatt PR, Chappard D, Hartmann B, Holst JJ, Rosenkilde MM, Irwin N, Mabilleau G. Enteroendocrine K cells exert complementary effects to control bone quality and mass in mice. J Bone Miner Res. July 2020;35(7):1363-1374.
2020	Ponte F, Kim H, Iyer S, Han L, Almeida M, Manolagas SC. Cxcl12 deletion in mesenchymal cells increases bone turnover and attenuates the loss of cortical bone caused by estrogen deficiency in mice. J Bone Miner Res. August 2020;35(8):1441-1451.
2020	Dennis EP, Edwards SM, Jackson RM, Hartley CL, Tsompani D, Capulli M, Teti A, Boot‐Handford RP, Young DA, Piróg KA, Briggs MD. CRELD2 is a novel LRP1 chaperone that regulates noncanonical WNT signaling in skeletal development. J Bone Miner Res. August 2020;35(8):1452-1469.
2020	Qian Z, Zhang Y, Kang X, Li H, Zhang Y, Jin X, Gao X, Xu M, Ma Z, Zhao L, Zhang Z, Sun H, Wu S. Postnatal conditional deletion of Bmal1 in osteoblasts enhances trabecular bone formation via increased BMP2 signals. J Bone Miner Res. August 2020;35(8):1481-1493.
2020	Ma Y, Elefteriou F. Brain‐derived acetylcholine maintains peak bone mass in adult female mice. J Bone Miner Res. August 2020;35(8):1562-1571.
2020	Yorgan TA, Rolvien T, Stürznickel J, Vollersen N, Lange F, Zhao W, Baranowsky A, Rosenthal L, Hermans‐Borgmeyer I, Sharaf A, Karsak M, David J, Oheim R, Amling M, Schinke T. Mice carrying a ubiquitous R235W mutation of Wnt1 display a bone‐specific phenotype. J Bone Miner Res. September 2020;35(9):1726-1737.
2020	Qi S, Sun X, Choi HK, Yao J, Wang L, Wu G, He Y, Pan J, Guan J, Liu F. FAK promotes early osteoprogenitor cell proliferation by enhancing mTORC1 signaling. J Bone Miner Res. September 2020;35(9):1798-1811.
2020	Lademann F, Weidner H, Tsourdi E, Kumar R, Rijntjes E, Köhrle J, Hofbauer LC, Rauner M. Disruption of BMP signaling prevents hyperthyroidism‐induced bone loss in male mice. J Bone Miner Res. October 2020;35(10):2058-2069.
2020	Duque G, Vidal C, Li W, Al Saedi A, Khalil M, Lim CK, Myers DE, Guillemin GJ. Picolinic acid, a catabolite of tryptophan, has an anabolic effect on bone in vivo. J Bone Miner Res. November 2020;35(11):2275-2288.
2020	Zhao G, Kim EW, Jiang J, Bhoot C, Charles KR, Baek J, Mohan S, Adams JS, Tetradis S, Lyons KM. CCN1/Cyr61 is required in osteoblasts for responsiveness to the anabolic activity of PTH. J Bone Miner Res. November 2020;35(11):2289-2300.
2020	Brun J, Andreasen CM, Ejersted C, Andersen TL, Caverzasio J, Thouverey C. PDGF receptor signaling in osteoblast lineage cells controls bone resorption through upregulation of Csf1 expression. J Bone Miner Res. December 2020;35(12):2458-2469.
2021	Wakamatsu T, Iwasaki Y, Yamamoto S, Matsuo K, Goto S, Narita I, Kazama JJ, Tanaka K, Ito A, Ozasa R, Nakano T, Miyakoshi C, Onishi Y, Fukuma S, Fukuhara S, Yamato H, Fukagawa M, Akizawa T. Type I angiotensin II receptor blockade reduces uremia‐induced deterioration of bone material properties. J Bone Miner Res. January 2021;36(1):67-79.
2021	Farrell M, Fairfield H, Costa S, D'Amico A, Falank C, Brooks DJ, Reagan MR. Sclerostin‐neutralizing antibody treatment rescues negative effects of rosiglitazone on mouse bone parameters. J Bone Miner Res. January 2021;36(1):158-169.
2021	Palmieri M, Kim H, Gomez‐Acevedo H, Que X, Tsimikas S, Jilka RL, Manolagas SC, Witztum JL, Ambrogini E. A neutralizing antibody targeting oxidized phospholipids promotes bone anabolism in chow‐fed young adult mice. J Bone Miner Res. January 2021;36(1):170-185.
2021	Hendrickx G, Fischer V, Liedert A, von Kroge S, Haffner‐Luntzer M, Brylka L, Pawlus E, Schweizer M, Yorgan T, Baranowsky A, Rolvien T, Neven M, Schumacher U, Beech DJ, Amling M, Ignatius A, Schinke T. Piezo1 inactivation in chondrocytes impairs trabecular bone formation. J Bone Miner Res. February 2021;36(2):369-384.
2021	Gerbaix M, Ammann P, Ferrari S. Mechanically driven counter‐regulation of cortical bone formation in response to sclerostin‐neutralizing antibodies. J Bone Miner Res. February 2021;36(2):385-399.
2021	Dietrich K, Fiedler IA, Kurzyukova A, López‐Delgado AC, McGowan LM, Geurtzen K, Hammond CL, Busse B, Knopf F. Skeletal biology and disease modeling in zebrafish. J Bone Miner Res. March 2021;36(3):436-458.
2021	Stegen S, Devignes C, Torrekens S, Van Looveren R, Carmeliet P, Carmeliet G. Glutamine metabolism in osteoprogenitors is required for bone mass accrual and PTH‐induced bone anabolism in male mice. J Bone Miner Res. March 2021;36(3):604-616.
2020	Campos JF, Mierzwa AGH, Freitas-Jesus M, Lazaretti-Castro M, Nonaka KO, Reginato RD. Mechanical vibration associated with intermittent PTH improves bone microarchitecture in ovariectomized rats. J Clin Densitom. July–September 2020;23(3):511-519.
2020	Ries C, Boese CK, Stürznickel J, Koehne T, Hubert J, Pastor M-F, Hahn M, Meier SL, Beil FT, Püschel K, Amling M, Rolvien T. Age-related changes of micro-morphological subchondral bone properties in the healthy femoral head. Osteoarthritis Cartilage. November 2020;28(11):1437-1447.
2020	Löffler MT, Sollmann N, Mei K, Valentinitsch A, Noël PB, Kirschke JS, Baum T. X-ray-based quantitative osteoporosis imaging at the spine. Osteoporos Int. February 2020;31(2):233-250.
2020	Gomes-Ferreira PHS, de Oliveira D, Frigério PB, de Souza Batista FR, Grandfield K, Okamoto R. Teriparatide improves microarchitectural characteristics of peri-implant bone in orchiectomized rats. Osteoporos Int. September 2020;31(9):1807-1815.
2021	Binkley N, Orwoll E, Chapurlat R, Langdahl BL, Scott BB, Giezek H, Santora AC. Randomized, controlled trial to assess the safety and efficacy of odanacatib in the treatment of men with osteoporosis. Osteoporos Int. January 2021;32(1):173-184.
2019	Mondal A, Nguyen C, Ma X, Elbanna AE, Carlson JM. Network models for characterization of trabecular bone. Phys Rev E. April 18, 2019;99(4):042406.
2020	Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, von der Mark K, Sakane C, Kaneko H, Komori T. Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. November 2020;16(11):e1009169.
2016	Torres AM, Matheny JB, Keaveny TM, Taylor D, Rimnac CM, Hernandez CJ. Material heterogeneity in cancellous bone promotes deformation recovery after mechanical failure. Proc Natl Acad Sci USA. March 15, 2016;113(11):2892-2897.
2020	Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, Matsushita M, Ara T, Yasuda H, Penninger JM, Takahashi N, Udagawa N, Kobayashi Y. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020;10:13751.
2020	Aggleton J. First-Hand Experience: A Methodology for Exploring Bone Architecture [PhD thesis]. Bristol, UK: University of Bristol; January 2020.
2015	Nguyen AM. Multiscale Mechanobiology of Primary Cilia [PhD thesis]. Columbia University; 2015.
2018	Moore ER. The Primary Cilium Encourages Osteogenic Behavior in Periosteal Osteochondroprogenitors and Osteocytes During Juvenile Skeletal Development and Adult Bone Adaptation [PhD thesis]. Columbia University; 2018.
2015	Goff M. The Role of Micro and Ultra-Structure in Microdamage Accumulation in Cancellous Bone [PhD thesis]. Ithaca, NY: Cornell University; August 2015.
2017	Cresswell EN. Spatial Regulation of Bone Formation in Functional Adaptation of Cancellous Bone [PhD thesis]. Ithaca, NY: Cornell University; May 2017.
2017	Matheny JB. Interactions Between Bone Remodeling and Microdamage in Cancellous Bone [PhD thesis]. Ithaca, NY: Cornell University; August 2017.
2018	Torres AM. Fatigue Behavior of Cancellous Bone, Microdamage Accumulation, and Biologically Inspired Cellular Solids [PhD thesis]. Ithaca, NY: Cornell University; August 2018.
2020	Luna M. The Influence of the Gut Microbiome on Bone and Joint Disease [PhD thesis]. Ithaca, NY: Cornell University; August 2020.
2019	Bullock WA. The Role of Wnt Signaling in Bone Mechanotransduction [PhD thesis]. Indianapolis, IN: Indiana University – Purdue University Indianapolis; November 2019.
2019	Davis HM. Molecular Mechanisms Underlying Osteocyte Apoptosis and the Associated Osteoclastogenesis in Cx43-Deficiency and Aging [PhD thesis]. Indiana University – Purdue University Indianapolis (IUPUI); June 2019.
2017	Hemmatian H. Does the Osteocyte Lacuna Affect Bone Adaptive Response in Aging? [PhD thesis]. Katholieke Universiteit Leuven; December 2017.
2014	Jameson JR. Characterization of Bone Material Properties and Microstructure in Osteogenesis Imperfecta/brittle Bone Disease [PhD thesis]. Marquette University; December 2014.
2016	Hunckler MD. Investigation of a Rabbit Ulnar Loading Model for Atypical Fractures in Cortical Bone During Long-Term Bisphosphonate Treatment [Master's thesis]. University of Notre Dame; December 2016.
2015	Clauser CA. In Vivo Tibial Loading of Healthy and Osteolathrytic Mice [Master's thesis]. Indianapolis, IN: Purdue University; May 2015.
2016	Hammond MA. The Influence of Collagen Crosslinking and Treadmill Exercise on the Mechanics, Composition, and Morphology of Bone At Multiple Length Scales [PhD thesis]. Purdue University; May 2016.
2015	Tan VPS. Effects of a School-Based Physical Activity Intervention on Adolescent Bone Strength, Structure and Density: The Health Promoting Secondary Schools (HPSS) Bone Health Study [PhD thesis]. Vancouver, BC: University of British Columbia; June 2015.
2016	Yee CSN. Determining the Role of Sost and Sostdc1 During Fracture Healing [PhD thesis]. Merced, CA: Merced, University of California; 2016.
2019	Nguyen C. Multiscale Network Characterization of the Strength and Robustness of Trabecular Bone [PhD thesis]. Santa Barbara, CA: Santa Barbara, University of California; September 2019.
2019	Mazur C. Osteocyte Regulation of Bone Quality in Homeostasis and in Skeletal Disease [PhD thesis]. San Francisco (UCSF), University of California; 2019.
2019	Poon A. Pamidronate Does Not Affect Cortical Porosity in Transgenic Mice Overexpressing Osteoblastic Gαs [Master's thesis]. University of Toronto; 2019.
2019	Putnam NE. Innate Immunity and Bone Remodeling During Staphylococcus Aureus Osteomyelitis [PhD thesis]. Nashville, TN: Vanderbilt University; June 30, 2019.
2016	Johnson MG. Endothelin-Converting Enzyme-1 Dependent Endothelin 1 Signaling in Osteogenesis [PhD thesis]. Madison, WI: University of Wisconsin; 2016.
2013	Tomlinson RE. The Role of Angiogenesis in Osteogenic Mechanical Loading [PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2013.

Year	Entry
1986	Eriksen EF. Normal and pathological remodeling of human trabecular bone: three dimensional reconstruction of the remodeling sequence in normals and in metabolic bone disease. Endocr Rev. November 1986;7(4):379-408.
1986	Garrahan NJ, Mellish RWE, Compston JE. A new method for the two-dimensional analysis of bone structure in human iliac crest biopsies. J Microsc (Oxford). June 1986;142(3):341-349.
1978	Singh I. The architecture of cancellous bone. J Anat. October 1978;127(2):305-310.
1995	Dobnig H, Turner RT. Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology. August 1995;136(8):3632-3638.
1987	Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR. Bone histomorphometry: standardization of nomenclature, symbols, and units: report of the ASBMR histomorphometry nomenclature committee. J Bone Miner Res. December 1987;2(6):595-610.
1969	Frost HM. Tetracycline-based histological analysis of bone remodeling. Calcif Tiss Res. 1969;3(1):211-237.
2008	Roschger P, Paschalis EP, Fratzl P, Klaushofer K. Bone mineralization density distribution in health and disease. Bone. March 2008;42(3):456-466.
1966	Arnold JS, Bartley MH, Tont SA, Jenkins DP. Skeletal changes in aging and disease. Clin Orthop Relat Res. December 1966;49:17-38.
1974	Whitehouse WJ. The quantitative morphology of anisotropic trabecular bone. J Microsc (Oxford). July 1974;101:153-168.
1977	Whitehouse WJ. Cancellous bone in the anterior part of the iliac crest. Calcif Tiss Res. December 1977;23(1):67-76.
1995	Boyce RW, Ebert DC, Youngs TA, Paddock CL, Mosekilde L, Stevens ML, Gundersen HJG. Unbiased estimation of vertebral trabecular connectivity in calcium-restricted ovariectomized minipigs. Bone. June 1995;16(6):637-642.
1984	Parfitt AM. The cellular basis of bone remodeling: the quantum concept reexamined in light of recent advances in the cell biology of bone. Calcif Tiss Int. March 1984;36(suppl 1):S37-S45.
1978	Carter DR, Spengler DM. Mechanical properties and composition of cortical bone. Clin Orthop Relat Res. September 1978;135:192-217.
1983	Parfitt AM, Mathews CH, Villanueva AR, Kleerekoper M, Frame B, Rao DS. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis: implications for the microanatomic and cellular mechanisms of bone loss. J Clin Invest. October 1983;72(4):1396-1409.
1982	Kragstrup J, Gundersen HJG, Melsen F, Mosekilde L. Estimation of the three-dimensional wall thickness of completed remodeling sites in iliac trabecular bone. Metab Bone Dis Rel Res. 1982;4(2):113-119.
1984	Keshawarz NM, Recker RR. Expansion of the medullary cavity at the expense of cortex in postmenopausal osteoporosis. Metab Bone Dis Rel Res. 1984;5(5):223-228.
2010	Zebaze RMD, Ghasem-Zadeh A, Bohte A, Iuliano-Burns S, Mirams M, Price RI, Mackie EJ, Seeman E. Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study. Lancet. May 15, 2010;375(9727):1729-1736.
1987	Compston JE, Mellish RWE, Garrahan NJ. Age-related changes in iliac crest trabecular microanatomic bone structure in man. Bone. 1987;8(5):289-292.
1987	Weinstein RS, Hutson MS. Decreased trabecular width and increased trabecular spacing contribute to bone loss with aging. Bone. 1987;8(3):137-142.
1970	Merz WA, Schenk RK. Quantitative structural analysis of human cancellous bone. Acta Anat. 1970;75(1):54-66.
1986	Cowin SC. Wolff’s law of trabecular architecture at remodeling equilibrium. J Biomech Eng. February 1986;108(1):83-88.