Targeted and nontargeted remodeling

Burr, D. B.<sup>1</sup>

Year	Entry
2009	Andersen TL, Sondergaard TE, Skorzynska KE, Dagnaes-Hansen F, Plesner TL, Hauge EM, Plesner T, Delaisse J-M. A physical mechanism for coupling bone resorption and formation in adult human bone. Am J Pathol. January 2009;174(1):239-247.
2002	Fazzalari NL, Kuliwaba JS, Forwood MR. Cancellous bone microdamage in the proximal femur: influence of age and osteoarthritis on damage morphology and regional distribution. Bone. December 2002;31(6):697-702.
2004	Hassenkam T, Fantner G, Cutroni J, Weaver J, Morse D, Hansma P. High-resolution AFM imaging of intact and fractured trabecular bone. Bone. July 2004;35(1):4-10.
2010	Emerton K, Hu B, Woo A, Sinofsky A, Hernandez C, Majeska R, Jepsen K, Schaffler M. Osteocyte apoptosis and control of bone resorption following ovariectomy in mice. Bone. March 2010;46(3):577-583.
2010	Shi X, Liu XS, Wang X, Guo XE, Niebur GL. Effects of trabecular type and orientation on microdamage susceptibility in trabecular bone. Bone. May 2010;46(5):1260-1266.
2010	Herman BC, Cardoso L, Majeska RJ, Jepsen KJ, Schaffler MB. Activation of bone remodeling after fatigue: differential response to linear microcracks and diffuse damage. Bone. October 2010;47(4):766-772.
2019	Burr DB. Stress concentrations and bone microdamage: John Currey's contributions to understanding the initiation and arrest of cracks in bone. Bone. October 2019;127:517-525.
2020	Lerebours C, Weinkamer R, Roschger A, Buenzli PR. Mineral density differences between femoral cortical bone and trabecular bone are not explained by turnover rate alone. Bone Rep. December 1, 2020;13:100731.
2003	Martin RB. Fatigue microdamage as an essential element of bone mechanics and biology. Calcif Tiss Int. August 2003;73(2):101-107.
2008	Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. November 2008;3(suppl 3):S131-S139.
2006	Black DM, Schwartz AV, Ensrud KE, Cauley JA, Levis S, Quandt SA, Satterfield S, Wallace RB, Bauer DC, Palermo L, Wehren LE, Lombardi A, Santora AC, Cummings SR; FLEX Research Group. Effects of continuing or stopping alendronate after 5 years of treatment: the fracture intervention trial long-term extension (FLEX): a randomized trial. JAMA. December 27, 2006;296(24):2927-2938.
2011	Mischinski S, Ural A. Finite element modeling of microcrack growth in cortical bone. J Appl Mech. July 2011;78(4):041016.
2010	Shi X, Liu XS, Wang X, Guo XE, Niebur GL. Type and orientation of yielded trabeculae during overloading of trabecular bone along orthogonal directions. J Biomech. September 17, 2010;43(13):2460-2466.
2003	Akkus O, Polyakova‐Akkus A, Adar F, Schaffler MB. Aging of microstructural compartments in human compact bone. J Bone Miner Res. June 2003;18(6):1012-1019.
2005	Warden SJ, Hurst JA, Sanders MS, Turner CH, Burr DB, Li J. Bone adaptation to a mechanical loading program significantly increases skeletal fatigue resistance. J Bone Miner Res. May 2005;20(5):809-816.
2006	Hernandez CJ, Gupta A, Keaveny TM. A biomechanical analysis of the effects of resorption cavities on cancellous bone strength. J Bone Miner Res. August 2006;21(8):1248-1255.
2009	Cardoso L, Herman BC, Verborgt O, Laudier D, Majeska RJ, Schaffler MB. Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue. J Bone Miner Res. April 2009;24(4):597-605.
2022	Harrison KD, Sales E, Hiebert BD, Panahifar A, Zhu N, Arnason T, Swekla KJ, Pivonka P, Chapman LD, Cooper DML. Direct assessment of rabbit cortical bone basic multicellular unit longitudinal erosion rate: a 4D synchrotron-based approach. J Bone Miner Res. November 2022;37(11):2244-2258.
2004	Rauch F, Glorieux FH. Osteogenesis imperfecta. Lancet. April 24, 2004;363(9418):1377-1385.
2007	Taylor D, Hazenberg JG, Lee TC. Living with cracks: damage and repair in human bone. Nat Mater. April 2007;6(4):263-268.
2003	Bouxsein ML. Bone quality: where do we go from here? Osteoporos Int. September 2003;14(suppl 5):S118-S127.
2007	Fratzl P, Weinkamer R. Nature’s hierarchical materials. Prog Mater Sci. November 2007;52(8):1263-1334.
2004	Pearson OM, Lieberman DE. The aging of Wolff's "law": ontogeny and responses to mechanical loading in cortical bone. Yearb Phys Anthropol. 2004;47:63-99.
2008	Willey JS. Radiation-Induced Osteoporosis: Bone Quantity, Architecture, and Increased Resorption Following Exposure to Ionizing Radiation [PhD thesis]. Clemson, SC: Clemson University; May 2008.
2017	Bowman LC. Whole Body Irradiation and Degradation of Structural and Functional Properties of Mouse Bone: X-Rays, Protons, and Heavy Ions [PhD thesis]. Clemson, SC: Clemson University; December 2017.
2009	Emerton KB. Osteocyte Apoptosis Initiation of Targeted Bone Remodeling After Estrogen Withdrawal [PhD thesis]. New York, NY: The City University of New York; 2009.
2007	Voide R. Functional Phenotyping of Bone: A Hierarchical Assessment of Bone Failure Characteristics [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2007.
2010	Wang JL. Effects of Aging and Remodeling on Bone Microdamage Formation [Master's thesis]. Atlanta, GA: Georgia Institute of Technology; December 2010.
2011	O'Neal JM. The Effects of Aging and Remodeling on Bone Quality and Microdamage [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2011.
2019	Bakr M. Parathyroid Hormone Effect on Facilitating Stress Fracture Repair [PhD thesis]. Brisbane, Australia: Griffith University; July 2019.
2017	Bakalova LP. Relating Cortical Bone Mechanics to Intracortical Pore Morphology, Distribution and Remodeling History Within the Fibula Diaphysis [Master's thesis]. University of Illinois at Urbana-Champaign; 2017.
2002	Kontulainen S. Training, Detraining and Bone: Effect of Exercise on Bone Mass and Structure With Special Reference to Maintenance of the Exercise-Induced Bone Gain [PhD thesis]. University of Jyväskylä; 2002.
2009	Karakolis T. Mechanical Induction of Bone Formation: Comparison Between Rat and Mouse Forelimb Models [Master's thesis]. Hamilton, ON: McMaster University; December 2009.
2008	Herman BC. Osteocytes and Activation of Bone Remodeling [PhD thesis]. Mount Sinai School of Medicine; 2008.
2007	Smith IO. The Effect of Grain Size, Microcracking and Grain Boundary Grooving on Osteoblast Attachment in Hydroxyapatite [PhD thesis]. East Lansing, MI: Michigan State University; 2007.
2004	Wang X. Measurement and Analysis of Microdamage in Bone [PhD thesis]. University of Notre Dame; December 2004.
2010	Shi X. Effects of Architecture on Microdamage Susceptibility in Trabecular Bone [PhD thesis]. University of Notre Dame; April 2010.
2011	Garrison JG. The Relative Importance of Stress State, Microarchitecture, and Damage Burden in the Failure Behavior of Trabecular Bone [PhD thesis]. University of Notre Dame; April 2011.
2013	Turnbull TL. The Spatial Distribution of Fatigue Microdamage Accumulation in Cortical Bone and Factors Influencing Fracture Risk [PhD thesis]. University of Notre Dame; July 2013.
2011	Agnew AM. Histomorphometry of the Elderly Rib: A Methodological Approach With Implications for Biomechanics, Function, and Fracture Risk [PhD thesis]. The Ohio State University; 2011.
2011	Rose D. The Use of Geographical Information Systems Software for the Spatial Analysis of Bone Microstructure [Master's thesis]. The Ohio State University; 2011.
2015	Hunter RL. Variation in Cortical Osteocyte Lacunar Density and Distribution: Implications for Bone Quality Assessment [PhD thesis]. The Ohio State University; 2015.
2022	Gupta SD. Mineralized Tissues At the Osteochondral Junction in Healthy and Osteoarthritic Joints: Advanced Microimaging and Mechanical Studies [PhD thesis]. University of Oulu; 2022.
2010	Janeiro C. The Effect of Bone Quality on Osteoclastic Bone Resorption [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; May 2010.
2018	Synek A. Predicting Habitual Activities from Bone Architecture Using a Biomechanical Approach [PhD thesis]. Vienna University of Technology; 2018.
2022	Davis RA. Investigating the Effects of Aging and Prolonged Opioid Use on Bone Histomorphometry, Quality, and Biomechanics [PhD thesis]. University of Akron; August 2022.
2016	Firminger CR. Effects of Minimalist Footwear and Stride Length Reduction on Metatarsal Strains and the Probability of Stress Fracture in Running [Master's thesis]. Calgary, AB: University of Calgary; July 2016.
2017	Fung A. Experimental Validation of Finite Element Predicted Bone Strain in the Human Metatarsal [Master's thesis]. Calgary, AB: University of Calgary; April 2017.
2019	Kroker AM. The Progression of Bone Microarchitecture Changes Following an Acute Knee Injury in Young Adults [PhD thesis]. Calgary, AB: University of Calgary; March 2019.
2020	Francis D. The Natural History of Bone Marrow Lesions and Cysts in the Dunkin-Hartley Guinea Pig Knee Osteoarthritis Model [Master's thesis]. Calgary, AB: University of Calgary; October 2020.
2020	Plett RM. Enhanced Longitudinal Analysis of Bone Strength Estimated by 3D Bone Imaging and the Finite Element Method [Master's thesis]. Calgary, AB: University of Calgary; October 2020.
2006	Rao SH. The Genetics of Osteogenesis Imperfecta and Potential Therapeutics in a Murine Model [PhD thesis]. Davis, University of California; 2006.
2007	Ruffoni D. Modeling of Material and Architectural Quality of Trabecular Bone [PhD thesis]. Liège, Belgique: Université de Liège; September 2007.
2009	Sahar ND. Investigating the Effects of Age and Exercise on Bone Composition and the Impact of Composition on Mechanical Integrity. [PhD thesis]. University of Michigan; 2009.
2021	Harrison KD. A Novel in Vivo Synchrotron Radiation Micro-CT Imaging Platform for the Direct Tracking of Remodeling Events in Cortical Bone [PhD thesis]. University of Saskatchewan; December 2021.
2013	Eleazer CD. The Interaction of Mechanical Loading and Metabolic Stress on Human Cortical Bone: Testing Anthropological Assumptions Using Cross-Sectional Geometry and Histomorphology [PhD thesis]. Knoxville, University of Tennessee; August 2013.
2016	Andronowski JM. Evaluating Differential Nuclear DNA Yield Rates Among Human Bone Tissue Types: A Synchrotron Micro-CT Approach [PhD thesis]. Knoxville, University of Tennessee; May 2016.

Year	Entry
1997	Han Z-H, Palnitkar S, Rao DS, Nelson D, Parfitt AM. Effects of ethnicity and age or menopause on the remodeling and turnover of iliac bone: implications for mechanisms of bone loss. J Bone Miner Res. April 1997;12(4):498-508.
2000	Verborgt O, Gibson GJ, Schaffler MB. Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. J Bone Miner Res. January 2000;15(1):60-67.
1998	Bentolila V, Boyce TM, Fyhrie DP, Drumb R, Skerry TM, Schaffler MB. Intracortical remodeling in adult rat long bones after fatigue loading. Bone. September 1998;23(3):275-281.
1996	Parfitt AM, Mundy GR, Roodman GD, Hughes DE, Boyce BF. A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates. J Bone Miner Res. February 1996;11(2):150-159.
1997	Noble BS, Stevens H, Loveridge N, Reeve J. Identification of apoptotic changes in osteocytes in normal and pathological human bone. Bone. March 1997;20(3):273-282.
1995	Forwood MR, Burr DB, Takano Y, Eastman DF, Smith PN, Schwardt JD. Risedronate treatment does not increase microdamage in the canine femoral neck. Bone. June 1995;16(6):643-650.
1989	Martin RB, Burr DB. Structure, Function, and Adaptation of Compact Bone. New York, NY: Raven Press; 1989.
1985	Burr DB, Martin RB, Schaffler MB, Radin EL. Bone remodeling in response to in vivo fatigue microdamage. J Biomech. 1985;18(3):189-200.
1996	Bronckers ALJJ, Goei W, Luo G, Karsenty G, D'Souza RN, Lyaruu DM, Burger EH. DNA fragmentation during bone formation in neonatal rodents assessed by transferase-mediated end labeling. J Bone Miner Res. September 1996;11(9):1281-1291.
1997	Tomkinson A, Reeve J, Shaw RW, Noble BS. The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone. J Clin Endocrinol Metab. September 1997;82(9):3128-3135.
1999	Burger EH, Klein-Nulend J. Mechanotransduction in bone: role of the lacunocanalicular network. FASEB J. May 1999;12(9001):S101-S112.
1960	Frost HM. Presence of microscopic cracks in vivo in bone. Henry Ford Hosp Med Bull. 1960;8(1):25-35.
1993	Burr DB. Remodeling and the repair of fatigue damage. Calcif Tiss Int. February 1993;53(suppl 1):S75-S81.
2000	Hirano T, Turner CH, Forwood MR, Johnston CC, Burr DB. Does suppression of bone turnover impair mechanical properties by allowing microdamage accumulation? Bone. July 2000;27(1):13-20.
1993	Burr DB, Martin RB. Calculating the probability that microcracks initiate resorption spaces. J Biomech. April–May 1993;26(4-5):613-616.
1996	Prendergast PJ, Huiskes R. Microdamage and osteocyte-lacuna strain in bone: a microstructural finite element analysis. J Biomech Eng. May 1996;118(2):240-246.
2000	Mashiba T, Hirano T, Turner CH, Forwood MR, Johnston CC, Burr DB. Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res. April 2000;15(4):613-620.
2001	Mashiba T, Turner CH, Hirano T, Forwood MR, Johnston CC, Burr DB. Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles. Bone. May 2001;28(5):524-531.