Preparation of on-axis cylindrical trabecular bone specimens using micro-CT imaging

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Wang, Xiang¹; Liu, Xiangyi¹; Niebur, Glen L.¹

Preparation of on-axis cylindrical trabecular bone specimens using micro-CT imaging

J Biomech Eng. February 2004;126(1):122-125

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Affiliations

¹Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana 46556
Abstract and keywords

The Orientation of trabecular bone specimens for mechanical testing must be carefully controlled. A method for accurately preparing on-axis cylindrical specimens using high-resolution micro-CT imaging was developed. Sixteen cylindrical specimens were prepared from eight bovine tibiae. High-resolution finite element models were generated from micro-CT images of parallelepipeds and used to determine the principal material coordinate system of each parallelepiped. A cylindrical specimen was then machined with a diamond coring bit. The resulting specimens were scanned again to evaluate the orientation. The average deviation between the principal fabric orientation and the longitudinal axis of the cylindrical specimen was only 4.70 +/- 3.11 degrees.

Keywords:
Links

DOI: 10.1115/1.1645866

PubMed: 15171139

WoS: 000221423400017

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2011	Wu Z. Measures of Bone Quality and Their Relationship to Bone Mechanical Properties [PhD thesis]. University of Notre Dame; December 2011.
2015	Coughlin TR. Mechanobiological Signals in Trabecular Bone and Marrow [PhD thesis]. University of Notre Dame; July 2015.
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2017	Kreipke TC. Structural, Mechanical, and Biological Relationships of Trabecular Bone in Osteoporosis [PhD thesis]. Notre Dame, IN: University of Notre Dame; April 2017.