A comparison of the elasticity of live, dead, and fixed brain tissue

Metz, Howard<sup>1</sup>; McElhaney, James<sup>1</sup>; Ommaya, Ayub K.<sup>1</sup>

Affiliations

¹National Institutes of Health Public Health Service U.S. Department of Health, Education, and Welfare. Bethesda, Md. 20014, U.S.A.

Abstract

The opposition to the intracranial expansion of a thin elastic cylinder in live, dead, and fixed brain tissue has been measured and compared. An analysis of the data, assuming an elastic material, indicates that the elastic modulus increases concavely upward with strain and varies between 1.0 × 10³ and 3.5 × 10³ dyn/cm² for the range of strain tested. Death and fixation of brain tissue increases the modulus but does not appear to change the manner in which it varies with strain.

Links

DOI: 10.1016/0021-9290(70)90017-5

PubMed: 5000415

WoS: A1970G827700006

History

Received: 1979-11-03

Cited Works (2)

Year	Entry
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Cited By (39)

Year	Entry
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1997	Arbogast KB, Margulies SS. Regional differences in mechanical properties of the porcine central nervous system. In: Proceedings of the 41st Stapp Car Crash Conference. November 13-14, 1997; Lake Buena Vista, FL. Warrendale, PA: Society of Automotive Engineers:293-300. SAE 973336.
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1994	Ruan JS. Impact Biomechanics of Head Injury by Mathematical Modeling [PhD thesis]. Detroit, MI: Wayne State University; 1994.
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2012	Makwana R. Development and Validation of a 3D Finite Element Model of Advanced Combat Helmet and Biomechanical Analysis of Human Head and Helmet Response to Primary Blast Insult [Master's thesis]. Detroit, MI: Wayne State University; May 2012.